P47290 (POTC_MYCGE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Spermidine/putrescine transport system permease protein PotC homolog

Gene names

Name:	potC
Ordered Locus Names:	MG044

Organism

Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195) [Complete proteome] [HAMAP]

Taxonomic identifier

243273 [NCBI]

Taxonomic lineage

Bacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma

Protein attributes

Sequence length	284 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the activity of the bacterial transport system of putrescine and spermidine By similarity.
Subcellular location	Cell membrane; Multi-pass membrane protein By similarity.
Sequence similarities	Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. Contains 1 ABC transmembrane type-1 domain.

Ontologies

Keywords
Biological process	Transport
Cellular component	Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	transporter activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 284	284	Spermidine/putrescine transport system permease protein PotC homolog		PRO_0000060185
Regions
	Transmembrane	13 – 33	21	Helical; Potential
	Transmembrane	76 – 96	21	Helical; Potential
	Transmembrane	116 – 136	21	Helical; Potential
	Transmembrane	143 – 163	21	Helical; Potential
	Transmembrane	189 – 209	21	Helical; Potential
	Transmembrane	242 – 262	21	Helical; Potential
	Domain	72 – 263	192	ABC transmembrane type-1

Sequences

	Sequence		Length	Mass (Da)
	P47290 [UniParc]. Last modified October 1, 1996. Version 1. Checksum: 2746C49F2C3AF175	FASTA	284	31,669
	10 20 30 40 50 60 MKKHFKNLIK NSYFFLLITL IYLPLLIVVL VSLNGSSSRG NIVLDFGNVL NPNPDSKSAY 70 80 90 100 110 120 LRLGETDFAT PLINSIIIGV ITVLVSVPIA VISAFALLRT RNALKKTIFG ITNFSLATPD 130 140 150 160 170 180 IITAISLVLL FANTWLSFNQ QLGFFTIITS HISFSVPYAL ILIYPKIQKL NPNLILASQD 190 200 210 220 230 240 LGYSPLKTFF HITLPYLMPS IFSAVLVVFA TSFDDYVITS LVQGSVKTIA TELYSFRKGI 250 260 270 280 KAWAIAFGSI LILISVLGVC LITLQKYLRE KRKEIIKIRQ WKNS

References

[1]

"The minimal gene complement of Mycoplasma genitalium." Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A., Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M., Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L., Nguyen D.T., Utterback T.R., Saudek D.M. , Phillips C.A., Merrick J.M., Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S., Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C. Science 270:397-403(1995) [PubMed: 7569993] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33530 / G-37 / NCTC 10195.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L43967 Genomic DNA. Translation: AAC71260.1.
PIR	H64204.
RefSeq	NP_072704.1. NC_000908.2.
3D structure databases
ProteinModelPortal	P47290.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	875282.
GenomeReviews	Gene locus MG044 in contig L43967_GR.
KEGG	mge:MG_044.
PATRIC	20009466. VBIMycGen98045_0043.
TIGR	MG044.
Phylogenomic databases
HOGENOM	HBG571698.
OMA	YSFNESQ.
PhylomeDB	P47290.
ProtClustDB	CLSK542116.
Enzyme and pathway databases
BioCyc	MGEN243273:MG_044-MONOMER.
Family and domain databases
InterPro	IPR000515. BPD_transp. [Graphical view]
KO	K11070.
Pfam	PF00528. BPD_transp_1. 1 hit. [Graphical view]
PROSITE	PS50928. ABC_TM1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

POTC_MYCGE

Accession

Primary (citable) accession number: P47290

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	October 1, 1996
Last modified:	January 25, 2012
This is version 71 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program