P47289 (POTB_MYCGE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Spermidine/putrescine transport system permease protein PotB homolog

Gene names

Name:	potB
Ordered Locus Names:	MG043

Organism

Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195) [Complete proteome] [HAMAP]

Taxonomic identifier

243273 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Tenericutes › Mollicutes › Mycoplasmatales › Mycoplasmataceae › Mycoplasma › Mycoplasma genitalium

Protein attributes

Sequence length	285 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the activity of the bacterial transport system of putrescine and spermidine By similarity.
Subcellular location	Cell membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. Contains 1 ABC transmembrane type-1 domain.

Ontologies

Keywords
Biological process	Transport
Cellular component	Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	transporter activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 285	285	Spermidine/putrescine transport system permease protein PotB homolog		PRO_0000060179
Regions
	Transmembrane	10 – 30	21	Helical; Potential
	Transmembrane	62 – 82	21	Helical; Potential
	Transmembrane	94 – 114	21	Helical; Potential
	Transmembrane	136 – 156	21	Helical; Potential
	Transmembrane	196 – 216	21	Helical; Potential
	Transmembrane	247 – 267	21	Helical; Potential
	Domain	58 – 268	211	ABC transmembrane type-1

Sequences

	Sequence		Length	Mass (Da)
	P47289 [UniParc]. Last modified October 1, 1996. Version 1. Checksum: DED3041909865D6B	FASTA	285	32,101
	10 20 30 40 50 60 MHIKKKYWLL LPFFLLMTIF FIIPMAWIIV SGLQSEDGAS ISQKYEPLVS GLGFFNSFWT 70 80 90 100 110 120 SLWISIVTVI VALLFSFPFC YFLSQSKNKI FKAFVISIAT VPIWSSFLIK LIGLKTLLDL 130 140 150 160 170 180 LIGLSLNRVG DNNLTFGSGY TLLGTIYLFT PFMFLPLYNH FCVLPKNLLL ASQDLGYNWI 190 200 210 220 230 240 YSFVKVVIPF SKTAMLSGIA LTFFPALTSV AIAQFLDNSN QAETLGNYIF TLGNNGYDSA 250 260 270 280 IERGRAAGAI IIAALITFAI YFTVVFLPKI VRIVHNKWKQ HEKAF

References

[1]

"The minimal gene complement of Mycoplasma genitalium." Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A., Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M., Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L., Nguyen D.T., Utterback T.R., Saudek D.M. , Phillips C.A., Merrick J.M., Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S., Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C. Science 270:397-403(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33530 / G-37 / NCTC 10195.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L43967 Genomic DNA. Translation: AAC71259.1.
PIR	G64204.
RefSeq	NP_072703.1. NC_000908.2.
3D structure databases
ProteinModelPortal	P47289.
ModBase	Search...
Protein-protein interaction databases
STRING	243273.MG_043.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC71259; AAC71259; MG_043.
GeneID	875492.
KEGG	mge:MG_043.
PATRIC	20009464. VBIMycGen98045_0042.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1176.
KO	K11071.
OMA	LRAYTWK.
ProtClustDB	CLSK782788.
Enzyme and pathway databases
BioCyc	MGEN243273:GH2R-82-MONOMER.
Family and domain databases
InterPro	IPR000515. BPD_transp. [Graphical view]
Pfam	PF00528. BPD_transp_1. 1 hit. [Graphical view]
PROSITE	PS50928. ABC_TM1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

POTB_MYCGE

Accession

Primary (citable) accession number: P47289

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	October 1, 1996
Last modified:	May 1, 2013
This is version 79 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program