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P47279 (GLPF_MYCGE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 91. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable glycerol uptake facilitator protein
Gene names
Name:glpF
Ordered Locus Names:MG033
OrganismMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195) [Complete proteome] [HAMAP]
Taxonomic identifier243273 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma

Protein attributes

Sequence length258 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Glycerol enters the cell via the glycerol diffusion facilitator protein. This membrane protein facilitates the movement of glycerol across the cytoplasmic membrane By similarity.

Subcellular location

Cell membrane; Multi-pass membrane protein Potential.

Domain

Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).

Sequence similarities

Belongs to the MIP/aquaporin (TC 1.A.8) family. [View classification]

Ontologies

Keywords
   Biological processGlycerol metabolism
Transport
   Cellular componentCell membrane
Membrane
   DomainRepeat
Transmembrane
Transmembrane helix
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycerol metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functiontransporter activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 258258Probable glycerol uptake facilitator protein
PRO_0000064087

Regions

Transmembrane11 – 3121Helical; Potential
Transmembrane50 – 7021Helical; Potential
Transmembrane95 – 11521Helical; Potential
Transmembrane152 – 17221Helical; Potential
Transmembrane180 – 20021Helical; Potential
Transmembrane233 – 25321Helical; Potential
Motif77 – 793NPA 1
Motif206 – 2083NPA 2

Sequences

Sequence LengthMass (Da)Tools
P47279 [UniParc].

Last modified November 1, 1997. Version 2.
Checksum: 238DBE6ABA4E1438

FASTA25827,667
        10         20         30         40         50         60 
MYFQNSTQLG WWFLAELIGT FILIIFGNGA VAQVNLKKMA TSETKAKFLT VALTWGIGVL 

        70         80         90        100        110        120 
FGVLTANAIF KGSGHLNPAI SLFYAINGSI KSPTALIWPG FVIGILAQFL GAMIAQTTLN 

       130        140        150        160        170        180 
FLFWKQLSST DPQTVLAMHC TSPSVFNITR NFLTEFIATL ILIGGVVAAS HFLHNNPNSV 

       190        200        210        220        230        240 
PPGFMGLWLV AGIIIAFGGA TGSAINPARD LGTRIVFQLT PIKNKDANWK YSWIPVIAPL 

       250 
SAGLVLSIII GFSPAPVL 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L43967 Genomic DNA. Translation: AAC71249.1.
RefSeqNP_072693.1. NC_000908.2.

3D structure databases

ProteinModelPortalP47279.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243273.MG_033.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC71249; AAC71249; MG_033.
GeneID875476.
KEGGmge:MG_033.
PATRIC20009442. VBIMycGen98045_0031.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0580.
KOK02440.
OMAGSSNWKY.
OrthoDBEOG6P8TRZ.

Enzyme and pathway databases

BioCycMGEN243273:GH2R-33-MONOMER.

Family and domain databases

Gene3D1.20.1080.10. 1 hit.
InterProIPR023271. Aquaporin-like.
IPR000425. MIP.
IPR022357. MIP_CS.
[Graphical view]
PANTHERPTHR19139. PTHR19139. 1 hit.
PfamPF00230. MIP. 1 hit.
[Graphical view]
PRINTSPR00783. MINTRINSICP.
SUPFAMSSF81338. SSF81338. 1 hit.
PROSITEPS00221. MIP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGLPF_MYCGE
AccessionPrimary (citable) accession number: P47279
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: November 1, 1997
Last modified: May 14, 2014
This is version 91 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Mycoplasma genitalium

Mycoplasma genitalium (strain G-37): entries and gene names