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P47279

- GLPF_MYCGE

UniProt

P47279 - GLPF_MYCGE

Protein

Probable glycerol uptake facilitator protein

Gene

glpF

Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 92 (01 Oct 2014)
      Sequence version 2 (01 Nov 1997)
      Previous versions | rss
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    Functioni

    Glycerol enters the cell via the glycerol diffusion facilitator protein. This membrane protein facilitates the movement of glycerol across the cytoplasmic membrane By similarity.By similarity

    GO - Molecular functioni

    1. transporter activity Source: InterPro

    GO - Biological processi

    1. glycerol metabolic process Source: UniProtKB-KW

    Keywords - Biological processi

    Glycerol metabolism, Transport

    Enzyme and pathway databases

    BioCyciMGEN243273:GH2R-33-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable glycerol uptake facilitator protein
    Gene namesi
    Name:glpF
    Ordered Locus Names:MG033
    OrganismiMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
    Taxonomic identifieri243273 [NCBI]
    Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
    ProteomesiUP000000807: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 258258Probable glycerol uptake facilitator proteinPRO_0000064087Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi243273.MG_033.

    Structurei

    3D structure databases

    ProteinModelPortaliP47279.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei11 – 3121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei50 – 7021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei95 – 11521HelicalSequence AnalysisAdd
    BLAST
    Transmembranei152 – 17221HelicalSequence AnalysisAdd
    BLAST
    Transmembranei180 – 20021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei233 – 25321HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi77 – 793NPA 1
    Motifi206 – 2083NPA 2

    Domaini

    Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).

    Sequence similaritiesi

    Keywords - Domaini

    Repeat, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0580.
    KOiK02440.
    OMAiGSSNWKY.
    OrthoDBiEOG6P8TRZ.

    Family and domain databases

    Gene3Di1.20.1080.10. 1 hit.
    InterProiIPR023271. Aquaporin-like.
    IPR000425. MIP.
    IPR022357. MIP_CS.
    [Graphical view]
    PANTHERiPTHR19139. PTHR19139. 1 hit.
    PfamiPF00230. MIP. 1 hit.
    [Graphical view]
    PRINTSiPR00783. MINTRINSICP.
    SUPFAMiSSF81338. SSF81338. 1 hit.
    PROSITEiPS00221. MIP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P47279-1 [UniParc]FASTAAdd to Basket

    « Hide

    MYFQNSTQLG WWFLAELIGT FILIIFGNGA VAQVNLKKMA TSETKAKFLT    50
    VALTWGIGVL FGVLTANAIF KGSGHLNPAI SLFYAINGSI KSPTALIWPG 100
    FVIGILAQFL GAMIAQTTLN FLFWKQLSST DPQTVLAMHC TSPSVFNITR 150
    NFLTEFIATL ILIGGVVAAS HFLHNNPNSV PPGFMGLWLV AGIIIAFGGA 200
    TGSAINPARD LGTRIVFQLT PIKNKDANWK YSWIPVIAPL SAGLVLSIII 250
    GFSPAPVL 258
    Length:258
    Mass (Da):27,667
    Last modified:November 1, 1997 - v2
    Checksum:i238DBE6ABA4E1438
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L43967 Genomic DNA. Translation: AAC71249.1.
    RefSeqiNP_072693.1. NC_000908.2.

    Genome annotation databases

    EnsemblBacteriaiAAC71249; AAC71249; MG_033.
    GeneIDi875476.
    KEGGimge:MG_033.
    PATRICi20009442. VBIMycGen98045_0031.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L43967 Genomic DNA. Translation: AAC71249.1 .
    RefSeqi NP_072693.1. NC_000908.2.

    3D structure databases

    ProteinModelPortali P47279.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 243273.MG_033.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC71249 ; AAC71249 ; MG_033 .
    GeneIDi 875476.
    KEGGi mge:MG_033.
    PATRICi 20009442. VBIMycGen98045_0031.

    Phylogenomic databases

    eggNOGi COG0580.
    KOi K02440.
    OMAi GSSNWKY.
    OrthoDBi EOG6P8TRZ.

    Enzyme and pathway databases

    BioCyci MGEN243273:GH2R-33-MONOMER.

    Family and domain databases

    Gene3Di 1.20.1080.10. 1 hit.
    InterProi IPR023271. Aquaporin-like.
    IPR000425. MIP.
    IPR022357. MIP_CS.
    [Graphical view ]
    PANTHERi PTHR19139. PTHR19139. 1 hit.
    Pfami PF00230. MIP. 1 hit.
    [Graphical view ]
    PRINTSi PR00783. MINTRINSICP.
    SUPFAMi SSF81338. SSF81338. 1 hit.
    PROSITEi PS00221. MIP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 33530 / G-37 / NCTC 10195.

    Entry informationi

    Entry nameiGLPF_MYCGE
    AccessioniPrimary (citable) accession number: P47279
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1996
    Last sequence update: November 1, 1997
    Last modified: October 1, 2014
    This is version 92 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Mycoplasma genitalium
      Mycoplasma genitalium (strain G-37): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3