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P47268

- RPOE_MYCGE

UniProt

P47268 - RPOE_MYCGE

Protein

Probable DNA-directed RNA polymerase subunit delta

Gene

rpoE

Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 77 (01 Oct 2014)
      Sequence version 1 (01 Feb 1996)
      Previous versions | rss
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    Functioni

    Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling By similarity.By similarity

    GO - Molecular functioni

    1. DNA-directed RNA polymerase activity Source: UniProtKB-KW

    GO - Biological processi

    1. regulation of transcription, DNA-templated Source: InterPro
    2. transcription, DNA-templated Source: InterPro

    Keywords - Molecular functioni

    Nucleotidyltransferase, Transferase

    Keywords - Biological processi

    Transcription

    Enzyme and pathway databases

    BioCyciMGEN243273:GH2R-22-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable DNA-directed RNA polymerase subunit delta
    Alternative name(s):
    RNAP delta factor
    Gene namesi
    Name:rpoE
    Ordered Locus Names:MG022
    OrganismiMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
    Taxonomic identifieri243273 [NCBI]
    Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
    ProteomesiUP000000807: Chromosome

    Subcellular locationi

    Keywords - Cellular componenti

    DNA-directed RNA polymerase

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 145145Probable DNA-directed RNA polymerase subunit deltaPRO_0000204318Add
    BLAST

    Interactioni

    Subunit structurei

    RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors By similarity.By similarity

    Protein-protein interaction databases

    STRINGi243273.MG_022.

    Family & Domainsi

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi93 – 14553Asp/Glu-rich (acidic)Add
    BLAST

    Sequence similaritiesi

    Belongs to the RpoE family.Curated

    Phylogenomic databases

    eggNOGiCOG3343.
    KOiK03048.
    OrthoDBiEOG6S26DH.

    Family and domain databases

    HAMAPiMF_00357. RNApol_bact_RpoE.
    InterProiIPR007759. DNA-dir_RNA_pol_delta/Asxl.
    [Graphical view]
    PfamiPF05066. HARE-HTH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P47268-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQLEYLNLIS QAKVIAEKQF KANPFSFETI WKEVVKHFKI SKQDEPSLIG    50
    RFYQDFLEDP NFVYLGDRKW KLRDFMKFDE WNKISQSMFV TKEIFEEGYE 100
    DLSNKKVEPE EGVGDFIMGN DGDDNETGSE IVQGLINDSF SEENQ 145
    Length:145
    Mass (Da):17,057
    Last modified:February 1, 1996 - v1
    Checksum:iC7A1901C94E2A41F
    GO

    Sequence cautioni

    The sequence AAC43196.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L43967 Genomic DNA. Translation: AAC71238.1.
    U01721 Unassigned DNA. Translation: AAC43196.1. Different initiation.
    PIRiD64202.
    RefSeqiNP_072682.1. NC_000908.2.

    Genome annotation databases

    EnsemblBacteriaiAAC71238; AAC71238; MG_022.
    GeneIDi875707.
    KEGGimge:MG_022.
    PATRICi20009420. VBIMycGen98045_0020.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L43967 Genomic DNA. Translation: AAC71238.1 .
    U01721 Unassigned DNA. Translation: AAC43196.1 . Different initiation.
    PIRi D64202.
    RefSeqi NP_072682.1. NC_000908.2.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 243273.MG_022.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC71238 ; AAC71238 ; MG_022 .
    GeneIDi 875707.
    KEGGi mge:MG_022.
    PATRICi 20009420. VBIMycGen98045_0020.

    Phylogenomic databases

    eggNOGi COG3343.
    KOi K03048.
    OrthoDBi EOG6S26DH.

    Enzyme and pathway databases

    BioCyci MGEN243273:GH2R-22-MONOMER.

    Family and domain databases

    HAMAPi MF_00357. RNApol_bact_RpoE.
    InterProi IPR007759. DNA-dir_RNA_pol_delta/Asxl.
    [Graphical view ]
    Pfami PF05066. HARE-HTH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 33530 / G-37 / NCTC 10195.
    2. "A survey of the Mycoplasma genitalium genome by using random sequencing."
      Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III
      J. Bacteriol. 175:7918-7930(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-95.
      Strain: ATCC 33530 / G-37 / NCTC 10195.

    Entry informationi

    Entry nameiRPOE_MYCGE
    AccessioniPrimary (citable) accession number: P47268
    Secondary accession number(s): Q49195
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1996
    Last sequence update: February 1, 1996
    Last modified: October 1, 2014
    This is version 77 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Mycoplasma genitalium
      Mycoplasma genitalium (strain G-37): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3