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P47268 (RPOE_MYCGE) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable DNA-directed RNA polymerase subunit delta
Alternative name(s):
RNAP delta factor
Gene names
Name:rpoE
Ordered Locus Names:MG022
OrganismMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195) [Complete proteome] [HAMAP]
Taxonomic identifier243273 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma

Protein attributes

Sequence length145 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling By similarity. HAMAP-Rule MF_00357

Subunit structure

RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors By similarity.

Sequence similarities

Belongs to the RpoE family.

Sequence caution

The sequence AAC43196.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processTranscription
   Cellular componentDNA-directed RNA polymerase
   Molecular functionNucleotidyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processregulation of transcription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-HAMAP

transcription, DNA-templated

Inferred from electronic annotation. Source: InterPro

   Molecular_functionDNA-directed RNA polymerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 145145Probable DNA-directed RNA polymerase subunit delta HAMAP-Rule MF_00357
PRO_0000204318

Regions

Compositional bias93 – 14553Asp/Glu-rich (acidic) HAMAP-Rule MF_00357

Sequences

Sequence LengthMass (Da)Tools
P47268 [UniParc].

Last modified February 1, 1996. Version 1.
Checksum: C7A1901C94E2A41F

FASTA14517,057
        10         20         30         40         50         60 
MQLEYLNLIS QAKVIAEKQF KANPFSFETI WKEVVKHFKI SKQDEPSLIG RFYQDFLEDP 

        70         80         90        100        110        120 
NFVYLGDRKW KLRDFMKFDE WNKISQSMFV TKEIFEEGYE DLSNKKVEPE EGVGDFIMGN 

       130        140 
DGDDNETGSE IVQGLINDSF SEENQ 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L43967 Genomic DNA. Translation: AAC71238.1.
U01721 Unassigned DNA. Translation: AAC43196.1. Different initiation.
PIRD64202.
RefSeqNP_072682.1. NC_000908.2.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243273.MG_022.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC71238; AAC71238; MG_022.
GeneID875707.
KEGGmge:MG_022.
PATRIC20009420. VBIMycGen98045_0020.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG3343.
KOK03048.
OrthoDBEOG6S26DH.
ProtClustDBPRK02363.

Enzyme and pathway databases

BioCycMGEN243273:GH2R-22-MONOMER.

Family and domain databases

HAMAPMF_00357. RNApol_bact_RpoE.
InterProIPR007759. DNA-dir_RNA_pol_delta/Asxl.
[Graphical view]
PfamPF05066. HARE-HTH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRPOE_MYCGE
AccessionPrimary (citable) accession number: P47268
Secondary accession number(s): Q49195
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: February 19, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Mycoplasma genitalium

Mycoplasma genitalium (strain G-37): entries and gene names