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Protein

Probable DNA-directed RNA polymerase subunit delta

Gene

rpoE

Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferase, Transferase
Biological processTranscription

Enzyme and pathway databases

BioCyciMGEN243273:G1GJ2-22-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Probable DNA-directed RNA polymerase subunit delta
Alternative name(s):
RNAP delta factor
Gene namesi
Name:rpoE
Ordered Locus Names:MG022
OrganismiMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Taxonomic identifieri243273 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
Proteomesi
  • UP000000807 Componenti: Chromosome

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002043181 – 145Probable DNA-directed RNA polymerase subunit deltaAdd BLAST145

Interactioni

Subunit structurei

RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors (By similarity).By similarity

Protein-protein interaction databases

STRINGi243273.MgenG_010200002771

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi93 – 145Asp/Glu-rich (acidic)Add BLAST53

Sequence similaritiesi

Belongs to the RpoE family.Curated

Phylogenomic databases

eggNOGiCOG3343 LUCA
KOiK03048
OrthoDBiPOG091H07LL

Family and domain databases

Gene3Di1.10.10.1250, 1 hit
HAMAPiMF_00357 RNApol_bact_RpoE, 1 hit
InterProiView protein in InterPro
IPR007759 HB1/Asxl_HTH
IPR038087 RNAP_delta_sf
IPR029757 RpoE
PfamiView protein in Pfam
PF05066 HARE-HTH, 1 hit
TIGRFAMsiTIGR04567 RNAP_delt_lowGC, 1 hit

Sequencei

Sequence statusi: Complete.

P47268-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQLEYLNLIS QAKVIAEKQF KANPFSFETI WKEVVKHFKI SKQDEPSLIG
60 70 80 90 100
RFYQDFLEDP NFVYLGDRKW KLRDFMKFDE WNKISQSMFV TKEIFEEGYE
110 120 130 140
DLSNKKVEPE EGVGDFIMGN DGDDNETGSE IVQGLINDSF SEENQ
Length:145
Mass (Da):17,057
Last modified:February 1, 1996 - v1
Checksum:iC7A1901C94E2A41F
GO

Sequence cautioni

The sequence AAC43196 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L43967 Genomic DNA Translation: AAC71238.1
U01721 Unassigned DNA Translation: AAC43196.1 Different initiation.
PIRiD64202
RefSeqiWP_009885918.1, NZ_AAGX01000010.1

Genome annotation databases

EnsemblBacteriaiAAC71238; AAC71238; MG_022
KEGGimge:MG_022

Similar proteinsi

Entry informationi

Entry nameiRPOE_MYCGE
AccessioniPrimary (citable) accession number: P47268
Secondary accession number(s): Q49195
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: March 28, 2018
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health