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P47268

- RPOE_MYCGE

UniProt

P47268 - RPOE_MYCGE

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Protein
Probable DNA-directed RNA polymerase subunit delta
Gene
rpoE, MG022
Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling By similarity.UniRule annotation

GO - Molecular functioni

  1. DNA-directed RNA polymerase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. regulation of transcription, DNA-templated Source: UniProtKB-HAMAP
  2. transcription, DNA-templated Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Transcription

Enzyme and pathway databases

BioCyciMGEN243273:GH2R-22-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable DNA-directed RNA polymerase subunit delta
Alternative name(s):
RNAP delta factor
Gene namesi
Name:rpoE
Ordered Locus Names:MG022
OrganismiMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Taxonomic identifieri243273 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000807: Chromosome

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 145145Probable DNA-directed RNA polymerase subunit deltaUniRule annotation
PRO_0000204318Add
BLAST

Interactioni

Subunit structurei

RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors By similarity.

Protein-protein interaction databases

STRINGi243273.MG_022.

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi93 – 14553Asp/Glu-rich (acidic)UniRule annotation
Add
BLAST

Sequence similaritiesi

Belongs to the RpoE family.

Phylogenomic databases

eggNOGiCOG3343.
KOiK03048.
OrthoDBiEOG6S26DH.

Family and domain databases

HAMAPiMF_00357. RNApol_bact_RpoE.
InterProiIPR007759. DNA-dir_RNA_pol_delta/Asxl.
[Graphical view]
PfamiPF05066. HARE-HTH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P47268-1 [UniParc]FASTAAdd to Basket

« Hide

MQLEYLNLIS QAKVIAEKQF KANPFSFETI WKEVVKHFKI SKQDEPSLIG    50
RFYQDFLEDP NFVYLGDRKW KLRDFMKFDE WNKISQSMFV TKEIFEEGYE 100
DLSNKKVEPE EGVGDFIMGN DGDDNETGSE IVQGLINDSF SEENQ 145
Length:145
Mass (Da):17,057
Last modified:February 1, 1996 - v1
Checksum:iC7A1901C94E2A41F
GO

Sequence cautioni

The sequence AAC43196.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L43967 Genomic DNA. Translation: AAC71238.1.
U01721 Unassigned DNA. Translation: AAC43196.1. Different initiation.
PIRiD64202.
RefSeqiNP_072682.1. NC_000908.2.

Genome annotation databases

EnsemblBacteriaiAAC71238; AAC71238; MG_022.
GeneIDi875707.
KEGGimge:MG_022.
PATRICi20009420. VBIMycGen98045_0020.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L43967 Genomic DNA. Translation: AAC71238.1 .
U01721 Unassigned DNA. Translation: AAC43196.1 . Different initiation.
PIRi D64202.
RefSeqi NP_072682.1. NC_000908.2.

3D structure databases

ModBasei Search...

Protein-protein interaction databases

STRINGi 243273.MG_022.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC71238 ; AAC71238 ; MG_022 .
GeneIDi 875707.
KEGGi mge:MG_022.
PATRICi 20009420. VBIMycGen98045_0020.

Phylogenomic databases

eggNOGi COG3343.
KOi K03048.
OrthoDBi EOG6S26DH.

Enzyme and pathway databases

BioCyci MGEN243273:GH2R-22-MONOMER.

Family and domain databases

HAMAPi MF_00357. RNApol_bact_RpoE.
InterProi IPR007759. DNA-dir_RNA_pol_delta/Asxl.
[Graphical view ]
Pfami PF05066. HARE-HTH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33530 / G-37 / NCTC 10195.
  2. "A survey of the Mycoplasma genitalium genome by using random sequencing."
    Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III
    J. Bacteriol. 175:7918-7930(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-95.
    Strain: ATCC 33530 / G-37 / NCTC 10195.

Entry informationi

Entry nameiRPOE_MYCGE
AccessioniPrimary (citable) accession number: P47268
Secondary accession number(s): Q49195
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: May 14, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Mycoplasma genitalium
    Mycoplasma genitalium (strain G-37): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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