Reviewed, UniProtKB/Swiss-Prot P47264 (Y018_MYCGE)

Names and origin

Protein names

Recommended name:
    Uncharacterized ATP-dependent helicase MG018
    EC=3.6.1.-

Gene names

Ordered Locus Names:

MG018

Organism

Mycoplasma genitalium [Complete proteome] [HAMAP]

Taxonomic identifier

2097 [NCBI]

Taxonomic lineage

Bacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma

Protein attributes

Sequence length	1031 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Sequence similarities

Belongs to the SNF2/RAD54 helicase family. Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain. Contains 1 SWIM-type zinc finger.

Ontologies

Keywords
Domain	Zinc-finger
Ligand	ATP-binding Metal-binding Nucleotide-binding Zinc
Molecular function	Helicase Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA binding Inferred from electronic annotation. Source: InterPro helicase activity Inferred from electronic annotation. Source: UniProtKB-KW zinc ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1031	1031	Uncharacterized ATP-dependent helicase MG018		PRO_0000074380
Regions
	Domain	590 – 751	162	Helicase ATP-binding
	Domain	868 – 1022	155	Helicase C-terminal
	Zinc finger	50 – 85	36	SWIM-type
	Nucleotide binding	603 – 610	8	ATP Potential
	Motif	702 – 705	4	DEAQ box
Experimental info
	Sequence conflict	893	1	D → S in AAD10571. Ref.3

Sequences

	Sequence		Length	Mass (Da)
	P47264-1 [UniParc]. Last modified May 2, 2006. Version 3. Checksum: DD83F049B64B3A39	FASTA	1,031	119,737
	10 20 30 40 50 60 MTVAEIKKLA LNNQVFNEAK ALLEKGNVIF PKKFLKRKKI IIEVLDGKVF KVQINLKTAA 70 80 90 100 110 120 AHLDCSCSND KQNCVHIIAA LLKYNDLKNQ DNKEFDLNKA DKLECKEVEI LIENVSLAIV 130 140 150 160 170 180 NGSWKLKIGF VINIDKVQTN TTALRFYCCD NKDVYFLHTE DEQLFRIALD KFNSVERQTL 190 200 210 220 230 240 LIFDQLNKTK QMQYENNSLL FNLDQFLSLV KEVKKPSLFL LNEDKTDNIL FLRSQHKING 250 260 270 280 290 300 LSHVCGFLNN KVFDFVSYNE KTKQIVLRLA YLNKFTDFKF PYNINIYKLA FGETLFFHFL 310 320 330 340 350 360 IHLKMNGFKN IFFQSDVVIV KESEYLPKMF LTIEFNTQKN KFITDAFFKY KNKNSNTLTT 370 380 390 400 410 420 VYPHRYYLAQ KTNTSNFNRL LFYEQALQRF YEELFQIDYL RRFENIPIKD KNQIALFKTV 430 440 450 460 470 480 FDDYKTIDLA ELKLTSNLLN YKQLHFSISD IKALKIEDRQ LKIEFKAGGI DLKLIKSVLS 490 500 510 520 530 540 NYYKGNAICI GEDGWYDLND ENAKALISFW SQIDLRNATC DANNNLLLAK YHLFEVVDTI 550 560 570 580 590 600 SKYTDVTNLL DEKTALQLKI ASENQFHLSL DNNQINNLRK YQKEGVKWIR ALEDNQFGGI 610 620 630 640 650 660 LADEMGLGKT AQVIFAMLDS YQSTKSLLPS LIIVPASLLL NWKSEFQKFA PHVKIVTANG 670 680 690 700 710 720 NFKERSQVYE SLKNQILLMS FNVLRSDIKW ISQKKFHYVV IDEAQGIKNE NSTVTKAAKK 730 740 750 760 770 780 IKGNFCLALT GTPIENRLLD LWSCFDFVLP NFLGNKKQFS DQFEKEKNDE SFQKLMKKTS 790 800 810 820 830 840 PFILRRTKNK VLKELPKKII TDIYVELSEE HQKLYDKQKT DGLKEIKESD AKNALNILSL 850 860 870 880 890 900 ILKLRHICSL VKDNDVNDFE DNSKANAALN IIYEALENKR KVILFTQFLD VIDCFKQTLK 910 920 930 940 950 960 NQKIDHLVFD GRKTVKNRNT IIQKFNSAKE PCVMLASLKA GGVGINLTAA EVVIHFDVWW 970 980 990 1000 1010 1020 NSAVENQATD RAHRIGQSKT VQVYRIIAKN TIEERVCQVQ NQKQELVKKT LVEDVNFFKS 1030 LSHEELLKLF E

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The minimal gene complement of Mycoplasma genitalium." Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A., Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M., Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L., Nguyen D.T., Utterback T.R., Saudek D.M. , Phillips C.A., Merrick J.M., Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S., Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C. Science 270:397-403(1995) [PubMed: 7569993] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33530 / G-37 / NCTC 10195.
[2]	Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A., Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M., Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L., Nguyen D.T., Utterback T.R., Saudek D.M. , Phillips C.A., Merrick J.M., Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S., Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: SEQUENCE REVISION.
[3]	"A survey of the Mycoplasma genitalium genome by using random sequencing." Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III J. Bacteriol. 175:7918-7930(1993) [PubMed: 8253680] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 640-740 AND 802-902. Strain: ATCC 33530 / G-37 / NCTC 10195.

Cross-references

Sequence databases
EMBLGenBankDDBJ	L43967 Genomic DNA. Translation: AAC71234.2. U02179 Genomic DNA. Translation: AAD12465.1. U01757 Genomic DNA. Translation: AAD10571.1.
PIR	G64201. H64201. T09676.
RefSeq	NP_072678.2.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	875220.
GenomeReviews	Gene locus MG018 in contig L43967_GR.
KEGG	mge:MG_018.
TIGR	MG018.
Phylogenomic databases
HOGENOM	P47264.
OMA	QVYRIIA
Enzyme and pathway databases
BioCyc	MGEN243273:MG_018-MON.
Family and domain databases
InterPro	IPR014001. DEAD-like_N. IPR001650. DNA/RNA_helicase_C. IPR014021. Helicase_SF1/SF2_ATP-bd. IPR000330. SNF2_N. IPR007527. Znf_SWIM. [Graphical view]
Pfam	PF00271. Helicase_C. 1 hit. PF00176. SNF2_N. 1 hit. PF04434. SWIM. 1 hit. [Graphical view]
SMART	SM00487. DEXDc. 1 hit. SM00490. HELICc. 1 hit. [Graphical view]
PROSITE	PS51192. HELICASE_ATP_BIND_1. 1 hit. PS51194. HELICASE_CTER. 1 hit. PS50966. ZF_SWIM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y018_MYCGE

Accession

Primary (citable) accession number: P47264
Secondary accession number(s): P47262 , P47263, Q49209, Q49302

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1996
Last sequence update:	May 2, 2006
Last modified:	November 3, 2009
This is version 57 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)