Uncharacterized ATP-dependent helicase MG018 - Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)

Preferred order of sections

Names and origin

Protein names

Recommended name:
Uncharacterized ATP-dependent helicase MG018
EC=3.6.4.-

Gene names

Ordered Locus Names:

MG018

Organism

Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195) [Complete proteome] [HAMAP]

Taxonomic identifier

243273 [NCBI]

Taxonomic lineage

Bacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma

Protein attributes

Sequence length	1031 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the SNF2/RAD54 helicase family.

Contains 1 helicase ATP-binding domain.

Contains 1 helicase C-terminal domain.

Contains 1 SWIM-type zinc finger.

Ontologies

Keywords
Domain	Zinc-finger
Ligand	ATP-binding Metal-binding Nucleotide-binding Zinc
Molecular function	Helicase Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA binding Inferred from electronic annotation. Source: InterPro helicase activity Inferred from electronic annotation. Source: UniProtKB-KW zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 1031

1031

Uncharacterized ATP-dependent helicase MG018

PRO_0000074380

Regions

Domain

590 – 751

162

Helicase ATP-binding

Domain

868 – 1022

155

Helicase C-terminal

Zinc finger

50 – 85

36

SWIM-type

Nucleotide binding

603 – 610

8

ATP Potential

Motif

702 – 705

4

DEAQ box

Experimental info

Sequence conflict

893

1

D → S in AAD10571. Ref.3

Sequences

Sequence

Length

Mass (Da)

Tools

P47264 [UniParc].

Last modified May 2, 2006. Version 3.
Checksum: DD83F049B64B3A39
Show »

FASTA

1,031

119,737

        10         20         30         40         50         60 
MTVAEIKKLA LNNQVFNEAK ALLEKGNVIF PKKFLKRKKI IIEVLDGKVF KVQINLKTAA 

        70         80         90        100        110        120 
AHLDCSCSND KQNCVHIIAA LLKYNDLKNQ DNKEFDLNKA DKLECKEVEI LIENVSLAIV 

       130        140        150        160        170        180 
NGSWKLKIGF VINIDKVQTN TTALRFYCCD NKDVYFLHTE DEQLFRIALD KFNSVERQTL 

       190        200        210        220        230        240 
LIFDQLNKTK QMQYENNSLL FNLDQFLSLV KEVKKPSLFL LNEDKTDNIL FLRSQHKING 

       250        260        270        280        290        300 
LSHVCGFLNN KVFDFVSYNE KTKQIVLRLA YLNKFTDFKF PYNINIYKLA FGETLFFHFL 

       310        320        330        340        350        360 
IHLKMNGFKN IFFQSDVVIV KESEYLPKMF LTIEFNTQKN KFITDAFFKY KNKNSNTLTT 

       370        380        390        400        410        420 
VYPHRYYLAQ KTNTSNFNRL LFYEQALQRF YEELFQIDYL RRFENIPIKD KNQIALFKTV 

       430        440        450        460        470        480 
FDDYKTIDLA ELKLTSNLLN YKQLHFSISD IKALKIEDRQ LKIEFKAGGI DLKLIKSVLS 

       490        500        510        520        530        540 
NYYKGNAICI GEDGWYDLND ENAKALISFW SQIDLRNATC DANNNLLLAK YHLFEVVDTI 

       550        560        570        580        590        600 
SKYTDVTNLL DEKTALQLKI ASENQFHLSL DNNQINNLRK YQKEGVKWIR ALEDNQFGGI 

       610        620        630        640        650        660 
LADEMGLGKT AQVIFAMLDS YQSTKSLLPS LIIVPASLLL NWKSEFQKFA PHVKIVTANG 

       670        680        690        700        710        720 
NFKERSQVYE SLKNQILLMS FNVLRSDIKW ISQKKFHYVV IDEAQGIKNE NSTVTKAAKK 

       730        740        750        760        770        780 
IKGNFCLALT GTPIENRLLD LWSCFDFVLP NFLGNKKQFS DQFEKEKNDE SFQKLMKKTS 

       790        800        810        820        830        840 
PFILRRTKNK VLKELPKKII TDIYVELSEE HQKLYDKQKT DGLKEIKESD AKNALNILSL 

       850        860        870        880        890        900 
ILKLRHICSL VKDNDVNDFE DNSKANAALN IIYEALENKR KVILFTQFLD VIDCFKQTLK 

       910        920        930        940        950        960 
NQKIDHLVFD GRKTVKNRNT IIQKFNSAKE PCVMLASLKA GGVGINLTAA EVVIHFDVWW 

       970        980        990       1000       1010       1020 
NSAVENQATD RAHRIGQSKT VQVYRIIAKN TIEERVCQVQ NQKQELVKKT LVEDVNFFKS 

      1030 
LSHEELLKLF E

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The minimal gene complement of Mycoplasma genitalium." Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A., Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M., Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L., Nguyen D.T., Utterback T.R., Saudek D.M. Venter J.C. Science 270:397-403(1995) [PubMed: 7569993] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33530 / G-37 / NCTC 10195.
[2]	Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A., Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M., Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L., Nguyen D.T., Utterback T.R., Saudek D.M. Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: SEQUENCE REVISION.
[3]	"A survey of the Mycoplasma genitalium genome by using random sequencing." Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III J. Bacteriol. 175:7918-7930(1993) [PubMed: 8253680] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 640-740 AND 802-902. Strain: ATCC 33530 / G-37 / NCTC 10195.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L43967 Genomic DNA. Translation: AAC71234.2. U02179 Genomic DNA. Translation: AAD12465.1. U01757 Genomic DNA. Translation: AAD10571.1.
PIR	G64201. H64201. T09676.
RefSeq	NP_072678.2. NC_000908.2.
3D structure databases
ProteinModelPortal	P47264.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	875220.
GenomeReviews	Gene locus MG018 in contig L43967_GR.
KEGG	mge:MG_018.
PATRIC	20009412. VBIMycGen98045_0016.
TIGR	MG018.
Phylogenomic databases
HOGENOM	HBG130009.
OMA	QVYRIIA.
PhylomeDB	P47264.
ProtClustDB	CLSK436719.
Enzyme and pathway databases
BioCyc	MGEN243273:MG_018-MONOMER.
Family and domain databases
InterPro	IPR014001. DEAD-like_helicase. IPR001650. Helicase_C. IPR000330. SNF2_N. IPR007527. Znf_SWIM. [Graphical view]
Pfam	PF00271. Helicase_C. 1 hit. PF00176. SNF2_N. 1 hit. PF04434. SWIM. 1 hit. [Graphical view]
SMART	SM00487. DEXDc. 1 hit. SM00490. HELICc. 1 hit. [Graphical view]
PROSITE	PS51192. HELICASE_ATP_BIND_1. 1 hit. PS51194. HELICASE_CTER. 1 hit. PS50966. ZF_SWIM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y018_MYCGE

Accession

Primary (citable) accession number: P47264
Secondary accession number(s): P47262

Q49302

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1996
Last sequence update:	May 2, 2006
Last modified:	January 25, 2012
This is version 71 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program

Relevant documents

Mycoplasma genitalium

Mycoplasma genitalium (strain G-37): entries and gene names

SIMILARITY comments

Index of protein domains and families

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Molecule processing

Regions

Experimental info

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

Entry information

Relevant documents