P47260 (Y014_MYCGE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative ABC transporter ATP-binding protein MG014

Gene names

Ordered Locus Names:

MG014

Organism

Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195) [Complete proteome] [HAMAP]

Taxonomic identifier

243273 [NCBI]

Taxonomic lineage

Bacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma

Protein attributes

Sequence length	623 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Subcellular location	Cell membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the ABC transporter superfamily. Contains 1 ABC transmembrane type-1 domain. Contains 1 ABC transporter domain.

Ontologies

Keywords
Biological process	Transport
Cellular component	Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Ligand	ATP-binding Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity, coupled to transmembrane movement of substances Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 623	623	Putative ABC transporter ATP-binding protein MG014		PRO_0000093235
Regions
	Transmembrane	27 – 47	21	Helical; Potential
	Transmembrane	81 – 101	21	Helical; Potential
	Transmembrane	157 – 177	21	Helical; Potential
	Transmembrane	181 – 201	21	Helical; Potential
	Transmembrane	266 – 286	21	Helical; Potential
	Transmembrane	307 – 327	21	Helical; Potential
	Domain	16 – 325	310	ABC transmembrane type-1
	Domain	365 – 611	247	ABC transporter
	Nucleotide binding	400 – 407	8	ATP Potential
Experimental info
	Sequence conflict	331 – 333	3	FNR → LIV in AAA03387. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	P47260 [UniParc]. Last modified February 1, 1996. Version 1. Checksum: F5D46215C9A95DDB	FASTA	623	69,537
	10 20 30 40 50 60 MGLVLKEFNN KIRTALILAP FFTFAQIVID LIIPSFLASA ISVVFSIDKL KQDESGGKTI 70 80 90 100 110 120 SVDFIGGANI NFANVREAQI VLATTVILLA LCGLFFGLIS IYCASYVSAN TSFLLRKKIF 130 140 150 160 170 180 AKLMRITTPS HDHYGSSTLL VRLTNDVYLM EVIAFDFLRL IIRAPLLFIG GLVFAVTTNQ 190 200 210 220 230 240 DMSISLLITF PLILLVIGIL NRKSIPLFKE NQKSVDKINE RVEEDVSGYK VIQSFNLHSF 250 260 270 280 290 300 TNNKFKIANE GWKKNSTSSL FINSLNIPFT FFLSSLTIII ALLLVFQLDS SVSVDPLPQD 310 320 330 340 350 360 AAIRPNIFAF FQYNFYIVLG FILTSLTMVN FNRSRVALGR IKDILSQPEI KTITNKDQKE 370 380 390 400 410 420 LLPTLEFRNI SFGLGNKNNN NFLQNLSFKF EAYKTYGIVG PTGSGKSLIA NIIGGLYEPN 430 440 450 460 470 480 EGEILIGGEK IQSIDSLYLS EMIGIVFQQN ILFKGTISSN IKIGIETRSD WKNQSDLQKN 490 500 510 520 530 540 EAMKNAAKIA CADTFIEKFS DSYDHNVEQL GKNLSGGQKQ RVAIARTLIT KPRILVFDDS 550 560 570 580 590 600 MSALDALTEK KVRENIENDL KLTTKIIISQ NINSIKHADK ILVIDNGRIV GFDSDQKLMK 610 620 NCSLYQKMKE SQKDLGGDFD AVN

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The minimal gene complement of Mycoplasma genitalium." Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A., Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M., Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L., Nguyen D.T., Utterback T.R., Saudek D.M. , Phillips C.A., Merrick J.M., Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S., Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C. Science 270:397-403(1995) [PubMed: 7569993] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33530 / G-37 / NCTC 10195.
[2]	"A survey of the Mycoplasma genitalium genome by using random sequencing." Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III J. Bacteriol. 175:7918-7930(1993) [PubMed: 8253680] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 227-333. Strain: ATCC 33530 / G-37 / NCTC 10195.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L43967 Genomic DNA. Translation: AAC71230.1. U02235 Genomic DNA. Translation: AAA03387.1.
PIR	E64201.
RefSeq	NP_072674.1. NC_000908.2.
3D structure databases
ProteinModelPortal	P47260.
ModBase	Search...
Proteomic databases
PRIDE	P47260.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	875485.
GenomeReviews	Gene locus MG014 in contig L43967_GR.
KEGG	mge:MG_014.
PATRIC	20009408. VBIMycGen98045_0014.
TIGR	MG014.
Phylogenomic databases
HOGENOM	HBG758042.
OMA	CADTFIE.
PhylomeDB	P47260.
ProtClustDB	CLSK542097.
Enzyme and pathway databases
BioCyc	MGEN243273:MG_014-MONOMER.
Family and domain databases
InterPro	IPR003439. ABC_transporter-like. IPR017871. ABC_transporter_CS. IPR017940. ABC_transporter_type1. IPR001140. ABC_transptr_TM_dom. IPR011527. ABC_transptrTM_dom_typ1. IPR003593. ATPase_AAA+_core. [Graphical view]
KO	K06147.
Pfam	PF00664. ABC_membrane. 1 hit. PF00005. ABC_tran. 1 hit. [Graphical view]
SMART	SM00382. AAA. 1 hit. [Graphical view]
SUPFAM	SSF90123. ABC_TM_1. 1 hit.
PROSITE	PS50929. ABC_TM1F. 1 hit. PS00211. ABC_TRANSPORTER_1. 1 hit. PS50893. ABC_TRANSPORTER_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y014_MYCGE

Accession

Primary (citable) accession number: P47260
Secondary accession number(s): Q49343

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1996
Last sequence update:	February 1, 1996
Last modified:	January 25, 2012
This is version 86 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program