P47258 (Y012_MYCGE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein MG012

Gene names

Ordered Locus Names:

MG012

Organism

Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195) [Complete proteome] [HAMAP]

Taxonomic identifier

243273 [NCBI]

Taxonomic lineage

Bacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma

Protein attributes

Sequence length	287 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Binds 2 manganese ions per subunit By similarity.
Sequence similarities	Belongs to the rimK family. Contains 1 ATP-grasp domain.

Ontologies

Keywords
Ligand	ATP-binding Manganese Metal-binding Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein modification process Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ligase activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 287	287	Uncharacterized protein MG012		PRO_0000205506
Regions
	Domain	115 – 287	173	ATP-grasp
	Nucleotide binding	135 – 187	53	ATP By similarity
	Nucleotide binding	141 – 187	47	ATP By similarity
Sites
	Metal binding	261	1	Manganese 1 By similarity
	Metal binding	261	1	Manganese 2 By similarity
	Metal binding	263	1	Manganese 2 By similarity

Sequences

	Sequence		Length	Mass (Da)
	P47258 [UniParc]. Last modified November 1, 1997. Version 2. Checksum: 7A14AF52A5AD7BBD	FASTA	287	32,733
	10 20 30 40 50 60 MKKINVVYNP AFNPISSKLN QTQLLKNASE ELDIELKFFT SFDINTTKAK ANLPFISNKI 70 80 90 100 110 120 LFMDKNIALA RWLESNGFEV INSSIGINNA DNKGLSHAII AQYPFIKQIK TLLGPQNFDR 130 140 150 160 170 180 EWNPVMLDVF INQIKQSMEF PVIVKSVFGS FGDYVFLCLD EQKLRKTLMS FNQQAIVQKY 190 200 210 220 230 240 ITCSKGESVR VIVVNNKVIG ALHTTNNSDF RSNLNKGAKA ERFFLNKEQE NLAVKISKVM 250 260 270 280 QLFYCGIDFL FDQDRSLIFC EVNPNVQLTR SSMYLNTNLA IELLKAI

References

[1]

"The minimal gene complement of Mycoplasma genitalium." Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A., Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M., Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L., Nguyen D.T., Utterback T.R., Saudek D.M. , Phillips C.A., Merrick J.M., Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S., Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C. Science 270:397-403(1995) [PubMed: 7569993] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33530 / G-37 / NCTC 10195.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L43967 Genomic DNA. Translation: AAC71228.1.
RefSeq	NP_072672.1. NC_000908.2.
3D structure databases
ProteinModelPortal	P47258.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	875213.
GenomeReviews	Gene locus MG012 in contig L43967_GR.
KEGG	mge:MG_012.
PATRIC	20009400. VBIMycGen98045_0012.
TIGR	MG012.
Phylogenomic databases
HOGENOM	HBG130004.
OMA	YFALAVI.
ProtClustDB	CLSK542096.
Enzyme and pathway databases
BioCyc	MGEN243273:MG_012-MONOMER.
Family and domain databases
InterPro	IPR011761. ATP-grasp. IPR013651. ATP-grasp_RimK-type. IPR013815. ATP_grasp_subdomain_1. IPR013816. ATP_grasp_subdomain_2. IPR004666. RpS6_RimK/Lys_biosynth_LsyX. [Graphical view]
Gene3D	G3DSA:3.30.1490.20. ATP_grasp_subdomain_1. 1 hit. G3DSA:3.30.470.20. ATP_grasp_subdomain_2. 1 hit.
KO	K05844.
Pfam	PF08443. RimK. 1 hit. [Graphical view]
TIGRFAMs	TIGR00768. RimK_fam. 1 hit.
PROSITE	PS50975. ATP_GRASP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y012_MYCGE

Accession

Primary (citable) accession number: P47258

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1996
Last sequence update:	November 1, 1997
Last modified:	January 25, 2012
This is version 57 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program