P47255 (Y009_MYCGE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized deoxyribonuclease MG009
EC=3.1.21.-

Gene names

Ordered Locus Names:

MG009

Organism

Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195) [Complete proteome] [HAMAP]

Taxonomic identifier

243273 [NCBI]

Taxonomic lineage

Bacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma

Protein attributes

Sequence length	262 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Putative deoxyribonuclease By similarity.
Cofactor	Binds 2 divalent metal cations per subunit By similarity.
Sequence similarities	Belongs to the TatD DNase family.

Ontologies

Keywords
Ligand	Metal-binding
Molecular function	Hydrolase Nuclease
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	endodeoxyribonuclease activity, producing 5'-phosphomonoesters Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 262	262	Uncharacterized deoxyribonuclease MG009		PRO_0000202006
Sites
	Metal binding	7	1	Divalent metal cation 1 By similarity
	Metal binding	9	1	Divalent metal cation 1 By similarity
	Metal binding	96	1	Divalent metal cation 1 By similarity
	Metal binding	96	1	Divalent metal cation 2 By similarity
	Metal binding	132	1	Divalent metal cation 2 By similarity
	Metal binding	156	1	Divalent metal cation 2 By similarity
	Metal binding	211	1	Divalent metal cation 1 By similarity

Sequences

	Sequence		Length	Mass (Da)
	P47255 [UniParc]. Last modified February 1, 1996. Version 1. Checksum: B8AC017F78C7FA18	FASTA	262	30,373
	10 20 30 40 50 60 MEYFDAHCHL NCEPLLSEIE KSIANFKLIN LKANVVGTDL DNSKIAVELA KKYPDLLKAT 70 80 90 100 110 120 IGIHPNDVHL VDFKKTKKQL NELLINNRNF ISCIGEYGFD YHYTTEFIEL QNKFFEMQFE 130 140 150 160 170 180 IAETNKLVHM LHIRDAHEKI YEILTRLKPT QPVIFHCFSQ DINIAKKLLS LKDLNIDIFF 190 200 210 220 230 240 SIPGIVTFKN AQALHEALKI IPSELLLSET DSPWLTPSPF RGKVNWPEYV VHTVSTVAEI 250 260 KKIEIAEMKR IIVKNAKKLF WH

References

[1]

"The minimal gene complement of Mycoplasma genitalium." Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A., Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M., Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L., Nguyen D.T., Utterback T.R., Saudek D.M. , Phillips C.A., Merrick J.M., Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S., Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C. Science 270:397-403(1995) [PubMed: 7569993] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33530 / G-37 / NCTC 10195.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L43967 Genomic DNA. Translation: AAC71225.1.
PIR	I64200.
RefSeq	NP_072669.1. NC_000908.2.
3D structure databases
ProteinModelPortal	P47255.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	875688.
GenomeReviews	Gene locus MG009 in contig L43967_GR.
KEGG	mge:MG_009.
PATRIC	20009394. VBIMycGen98045_0009.
TIGR	MG009.
Phylogenomic databases
HOGENOM	HBG629833.
OMA	KMNIVGF.
PhylomeDB	P47255.
ProtClustDB	CLSK542093.
Enzyme and pathway databases
BioCyc	MGEN243273:MG_009-MONOMER.
Family and domain databases
InterPro	IPR012278. DNase_TatD. IPR018228. DNase_TatD-rel_CS. IPR015991. DNase_TatD_bac-type. IPR001130. TatD_superfamily. [Graphical view]
KO	K03424.
PANTHER	PTHR10060. TatD_DNase. 1 hit.
Pfam	PF01026. TatD_DNase. 1 hit. [Graphical view]
PIRSF	PIRSF005902. DNase_TatD. 1 hit.
TIGRFAMs	TIGR00010. TIGR00010. 1 hit.
PROSITE	PS01137. TATD_1. 1 hit. PS01090. TATD_2. False negative. PS01091. TATD_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y009_MYCGE

Accession

Primary (citable) accession number: P47255

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1996
Last sequence update:	February 1, 1996
Last modified:	January 25, 2012
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program