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Protein

Elongation factor Ts

Gene

tsf

Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity).By similarity

GO - Molecular functioni

  1. translation elongation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Elongation factor

Keywords - Biological processi

Protein biosynthesis

Enzyme and pathway databases

BioCyciMGEN243273:GH2R-487-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor Ts
Short name:
EF-Ts
Gene namesi
Name:tsf
Ordered Locus Names:MG433
OrganismiMycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Taxonomic identifieri243273 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000807: Chromosome

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 298298Elongation factor TsPRO_0000161151Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi243273.MG_433.

Structurei

3D structure databases

ProteinModelPortaliP47246.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni79 – 824Involved in Mg(2+) ion dislocation from EF-TuBy similarity

Sequence similaritiesi

Belongs to the EF-Ts family.Curated

Phylogenomic databases

eggNOGiCOG0264.
KOiK02357.
OMAiHSQIAVI.
OrthoDBiEOG66B42N.

Family and domain databases

Gene3Di3.30.479.20. 3 hits.
HAMAPiMF_00050. EF_Ts.
InterProiIPR001816. Transl_elong_EFTs/EF1B.
IPR014039. Transl_elong_EFTs/EF1B_dimer.
IPR018101. Transl_elong_Ts_CS.
IPR009060. UBA-like.
IPR000449. UBA/Ts_N.
[Graphical view]
PANTHERiPTHR11741. PTHR11741. 1 hit.
PfamiPF00889. EF_TS. 1 hit.
PF00627. UBA. 1 hit.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 1 hit.
SSF54713. SSF54713. 2 hits.
TIGRFAMsiTIGR00116. tsf. 1 hit.
PROSITEiPS01126. EF_TS_1. 1 hit.
PS01127. EF_TS_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P47246-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MATKIELIKE LRKSTQASVM DCKQALEKNN DDFEKAVKWL RENGIVKSTK
60 70 80 90 100
KLNKVASEGI IVLKSNLHKA IMVEINSQTD FVAKNQELKE FSDLMLEKIF
110 120 130 140 150
EKVNPKTELV EIEKIQINND EKVSEKLALI ASKTDEKIVL RRVVVFETKT
160 170 180 190 200
NQIFTYLHAN KRIGVIIEIQ GKLNEDDGKH LAMHIAANSP QFIDQSDVNQ
210 220 230 240 250
TWLQNERNII RSQAELEVKE NPKKAIFLEK TIEGRVNKLL IDTCLINQKY
260 270 280 290
LIDETKTIGQ FLKEKQAKVL KFIRYEVGEG IIKETVDFVS EVNAQIKQ
Length:298
Mass (Da):34,265
Last modified:February 1, 1996 - v1
Checksum:i014E423EBD2A5F7B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L43967 Genomic DNA. Translation: AAC72454.1.
PIRiH64247.
RefSeqiNP_073104.1. NC_000908.2.

Genome annotation databases

EnsemblBacteriaiAAC72454; AAC72454; MG_433.
GeneIDi875620.
KEGGimge:MG_433.
PATRICi20010452. VBIMycGen98045_0499.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L43967 Genomic DNA. Translation: AAC72454.1.
PIRiH64247.
RefSeqiNP_073104.1. NC_000908.2.

3D structure databases

ProteinModelPortaliP47246.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243273.MG_433.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC72454; AAC72454; MG_433.
GeneIDi875620.
KEGGimge:MG_433.
PATRICi20010452. VBIMycGen98045_0499.

Phylogenomic databases

eggNOGiCOG0264.
KOiK02357.
OMAiHSQIAVI.
OrthoDBiEOG66B42N.

Enzyme and pathway databases

BioCyciMGEN243273:GH2R-487-MONOMER.

Family and domain databases

Gene3Di3.30.479.20. 3 hits.
HAMAPiMF_00050. EF_Ts.
InterProiIPR001816. Transl_elong_EFTs/EF1B.
IPR014039. Transl_elong_EFTs/EF1B_dimer.
IPR018101. Transl_elong_Ts_CS.
IPR009060. UBA-like.
IPR000449. UBA/Ts_N.
[Graphical view]
PANTHERiPTHR11741. PTHR11741. 1 hit.
PfamiPF00889. EF_TS. 1 hit.
PF00627. UBA. 1 hit.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 1 hit.
SSF54713. SSF54713. 2 hits.
TIGRFAMsiTIGR00116. tsf. 1 hit.
PROSITEiPS01126. EF_TS_1. 1 hit.
PS01127. EF_TS_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33530 / G-37 / NCTC 10195.

Entry informationi

Entry nameiEFTS_MYCGE
AccessioniPrimary (citable) accession number: P47246
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: January 7, 2015
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Mycoplasma genitalium
    Mycoplasma genitalium (strain G-37): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.