P47246 (EFTS_MYCGE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Elongation factor Ts
Short name=EF-Ts

Gene names

Name:	tsf
Ordered Locus Names:	MG433

Organism

Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195) [Complete proteome] [HAMAP]

Taxonomic identifier

243273 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Tenericutes › Mollicutes › Mycoplasmatales › Mycoplasmataceae › Mycoplasma › Mycoplasma genitalium

Protein attributes

Sequence length	298 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome By similarity. HAMAP-Rule MF_00050
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the EF-Ts family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Molecular function	Elongation factor
Technical term	Complete proteome
Gene Ontology (GO)
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	translation elongation factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 298	298	Elongation factor Ts HAMAP-Rule MF_00050		PRO_0000161151
Regions
	Region	79 – 82	4	Involved in Mg(2+) ion dislocation from EF-Tu By similarity

Sequences

	Sequence		Length	Mass (Da)
	P47246 [UniParc]. Last modified February 1, 1996. Version 1. Checksum: 014E423EBD2A5F7B	FASTA	298	34,265
	10 20 30 40 50 60 MATKIELIKE LRKSTQASVM DCKQALEKNN DDFEKAVKWL RENGIVKSTK KLNKVASEGI 70 80 90 100 110 120 IVLKSNLHKA IMVEINSQTD FVAKNQELKE FSDLMLEKIF EKVNPKTELV EIEKIQINND 130 140 150 160 170 180 EKVSEKLALI ASKTDEKIVL RRVVVFETKT NQIFTYLHAN KRIGVIIEIQ GKLNEDDGKH 190 200 210 220 230 240 LAMHIAANSP QFIDQSDVNQ TWLQNERNII RSQAELEVKE NPKKAIFLEK TIEGRVNKLL 250 260 270 280 290 IDTCLINQKY LIDETKTIGQ FLKEKQAKVL KFIRYEVGEG IIKETVDFVS EVNAQIKQ

References

[1]

"The minimal gene complement of Mycoplasma genitalium." Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A., Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M., Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L., Nguyen D.T., Utterback T.R., Saudek D.M. , Phillips C.A., Merrick J.M., Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S., Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C. Science 270:397-403(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33530 / G-37 / NCTC 10195.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L43967 Genomic DNA. Translation: AAC72454.1.
PIR	H64247.
RefSeq	NP_073104.1. NC_000908.2.
3D structure databases
ProteinModelPortal	P47246.
ModBase	Search...
Protein-protein interaction databases
STRING	243273.MG_433.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC72454; AAC72454; MG_433.
GeneID	875620.
KEGG	mge:MG_433.
PATRIC	20010452. VBIMycGen98045_0499.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0264.
KO	K02357.
OMA	YLHGTRI.
ProtClustDB	PRK09377.
Enzyme and pathway databases
BioCyc	MGEN243273:GH2R-485-MONOMER.
Family and domain databases
Gene3D	3.30.479.20. 3 hits.
HAMAP	MF_00050. EF_Ts.
InterPro	IPR001816. Transl_elong_EFTs/EF1B. IPR014039. Transl_elong_EFTs/EF1B_dimer. IPR018101. Transl_elong_Ts_CS. IPR009060. UBA-like. IPR000449. UBA/transl_elong_EF1B_N. [Graphical view]
PANTHER	PTHR11741. PTHR11741. 1 hit.
Pfam	PF00889. EF_TS. 1 hit. PF00627. UBA. 1 hit. [Graphical view]
SUPFAM	SSF54713. EF_TS. 1 hit. SSF46934. UBA_like. 1 hit.
TIGRFAMs	TIGR00116. tsf. 1 hit.
PROSITE	PS01126. EF_TS_1. 1 hit. PS01127. EF_TS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

EFTS_MYCGE

Accession

Primary (citable) accession number: P47246

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1996
Last sequence update:	February 1, 1996
Last modified:	May 1, 2013
This is version 88 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program