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Protein

60S ribosomal protein L22

Gene

Rpl22

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

Heparin-binding, RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L22
Gene namesi
Name:Rpl22
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi621189. Rpl22.

Subcellular locationi

GO - Cellular componenti

  • cytosolic large ribosomal subunit Source: RGD
  • ribosome Source: RGD
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00002155042 – 12860S ribosomal protein L22Add BLAST127

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei62PhosphothreonineBy similarity1
Modified residuei66PhosphoserineBy similarity1
Modified residuei69N6-succinyllysineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP47198.
PRIDEiP47198.

Interactioni

Protein-protein interaction databases

BioGridi249640. 1 interactor.
IntActiP47198. 2 interactors.
MINTiMINT-4576885.
STRINGi10116.ENSRNOP00000014905.

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi120 – 128Asp/Glu-rich (highly acidic)9

Sequence similaritiesi

Belongs to the ribosomal protein L22e family.Curated

Phylogenomic databases

eggNOGiKOG3434. Eukaryota.
ENOG4111UVJ. LUCA.
HOGENOMiHOG000198396.
HOVERGENiHBG004373.
InParanoidiP47198.
KOiK02891.
PhylomeDBiP47198.

Family and domain databases

InterProiIPR002671. Ribosomal_L22e.
[Graphical view]
PANTHERiPTHR10064. PTHR10064. 1 hit.
PfamiPF01776. Ribosomal_L22e. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P47198-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPVKKLVAK GGKKKKQVLK FTLDCTHPVE DGIMDAANFE QFLQERIKVN
60 70 80 90 100
GKAGNLGGGV VTIERSKSKI TVTSEEPFSK RYLKYLTKKY LKKNNLRDWL
110 120
RVVANSKESY ELRYFQINQD EEEEEDED
Length:128
Mass (Da):14,789
Last modified:January 23, 2007 - v2
Checksum:iFC29D8BE6EF8221F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X78444 mRNA. Translation: CAA55204.1.
PIRiS52084.
RefSeqiNP_112366.1. NM_031104.1.
UniGeneiRn.198306.
Rn.21738.

Genome annotation databases

GeneIDi81768.
KEGGirno:81768.
UCSCiRGD:621189. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X78444 mRNA. Translation: CAA55204.1.
PIRiS52084.
RefSeqiNP_112366.1. NM_031104.1.
UniGeneiRn.198306.
Rn.21738.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi249640. 1 interactor.
IntActiP47198. 2 interactors.
MINTiMINT-4576885.
STRINGi10116.ENSRNOP00000014905.

Proteomic databases

PaxDbiP47198.
PRIDEiP47198.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi81768.
KEGGirno:81768.
UCSCiRGD:621189. rat.

Organism-specific databases

CTDi6146.
RGDi621189. Rpl22.

Phylogenomic databases

eggNOGiKOG3434. Eukaryota.
ENOG4111UVJ. LUCA.
HOGENOMiHOG000198396.
HOVERGENiHBG004373.
InParanoidiP47198.
KOiK02891.
PhylomeDBiP47198.

Miscellaneous databases

PROiP47198.

Family and domain databases

InterProiIPR002671. Ribosomal_L22e.
[Graphical view]
PANTHERiPTHR10064. PTHR10064. 1 hit.
PfamiPF01776. Ribosomal_L22e. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRL22_RAT
AccessioniPrimary (citable) accession number: P47198
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: January 23, 2007
Last modified: July 6, 2016
This is version 87 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Miscellaneous

Binds to Epstein-Barr virus small RNAs and to heparin.By similarity

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.