Hexose transporter HXT16 - Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Contribute

Send feedback

Read comments (?) or add your own

P47185 (HXT16_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 90. History...

Clusters with 100%, 90%, 50% identity |

Documents (3) |

Third-party data

text xml rdf/xml gff fasta

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
Hexose transporter HXT16

Gene names

Name:	HXT16
Ordered Locus Names:	YJR158W
ORF Names:	J2260

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces ›

Protein attributes

Sequence length	567 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Probable glucose transporter.
Subcellular location	Membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification]

Ontologies

Keywords
Biological process	Sugar transport Transport
Cellular component	Membrane
Domain	Repeat Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from sequence model PubMed 12192589. Source: SGD plasma membrane Inferred from sequence or structural similarity PubMed 8929273. Source: SGD
Molecular_function	fructose transmembrane transporter activity Inferred from genetic interaction PubMed 10618490. Source: SGD glucose transmembrane transporter activity Inferred from genetic interaction PubMed 10618490. Source: SGD mannose transmembrane transporter activity Inferred from genetic interaction PubMed 10618490. Source: SGD
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 567

567

Hexose transporter HXT16

PRO_0000050405

Regions

Topological domain

1 – 55

Cytoplasmic Potential

Transmembrane

56 – 76

Helical; Name=1; Potential

Topological domain

77 – 112

Extracellular Potential

Transmembrane

113 – 133

Helical; Name=2; Potential

Topological domain

134 – 139

Cytoplasmic Potential

Transmembrane

140 – 160

Helical; Name=3; Potential

Topological domain

161 – 170

Extracellular Potential

Transmembrane

171 – 191

Helical; Name=4; Potential

Topological domain

192 – 197

Cytoplasmic Potential

Transmembrane

198 – 218

Helical; Name=5; Potential

Topological domain

219 – 232

Extracellular Potential

Transmembrane

233 – 253

Helical; Name=6; Potential

Topological domain

254 – 336

Cytoplasmic Potential

Transmembrane

337 – 353

Helical; Name=7; Potential

Topological domain

354 – 359

Extracellular Potential

Transmembrane

360 – 377

Helical; Name=8; Potential

Topological domain

378 – 384

Cytoplasmic Potential

Transmembrane

385 – 405

Helical; Name=9; Potential

Topological domain

406 – 427

Extracellular Potential

Transmembrane

428 – 448

Helical; Name=10; Potential

Topological domain

449 – 465

Cytoplasmic Potential

Transmembrane

466 – 486

Helical; Name=11; Potential

Topological domain

487

Extracellular Potential

Transmembrane

488 – 508

Helical; Name=12; Potential

Topological domain

509 – 567

Cytoplasmic Potential

Sequences

Sequence

Length

Mass (Da)

Tools

P47185 [UniParc].

Last modified February 1, 1996. Version 1.
Checksum: B9C3C21B97528A4D
Show »

FASTA

567

62,920

        10         20         30         40         50         60 
MASEQSSPEI NADNLNSSAA DVHVQPPGEK EWSDGFYDKE VINGNTPDAP KRGFLGYLII 

        70         80         90        100        110        120 
YLLCYPVSFG GFLPGWDSGI TAGFINMDNF KMNFGSYKHS TGEYYLSNVR MGLLVAMFSV 

       130        140        150        160        170        180 
GCSIGGVAFA RLADTLGRRL AIVIVVLVYM VGAIIQISSN HKWYQYFVGK IIYGLGAGGC 

       190        200        210        220        230        240 
SVLCPMLLSE IAPTDLRGGL VSLYQLNMTF GIFLGYCSVY GTRKYSNTAQ WRIPVGLCFL 

       250        260        270        280        290        300 
WALIIIVGML LVPESPRYLI ECERHEEACV SIAKIDKVSP EDPWVLKQAD EINAGVLAQR 

       310        320        330        340        350        360 
ELGEASWKEL FSVKTKVLQR LITGILVQTF LQLTGENYFF FYGTTIFKSV GLTDGFETSI 

       370        380        390        400        410        420 
VLGTVNFFST IIAVMVVDKI GRRKCLLFGA ASMMACMVIF ASIGVKCLYP HGQDGPSSKG 

       430        440        450        460        470        480 
AGNAMIVFTC FYIFCFATTW APVAYIVVAE SFPSKVKSKA MSISTAFNWL WQFLIGFFTP 

       490        500        510        520        530        540 
FITGSIHFYY GYVFVGCLVA MFLYVFFFLP ETIGLSLEET QLLYEEGIKP WKSASWVPPS 

       550        560 
RRGASSRETE AKKKSWKEVL KFPKSFN

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X." Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K. Karpfinger-Hartl L. EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z49658 Genomic DNA. Translation: CAA89691.1. BK006943 Genomic DNA. Translation: DAA08942.1.
PIR	S57187.
RefSeq	NP_012692.3. NM_001181816.3.
3D structure databases
ProteinModelPortal	P47185.
SMR	P47185. Positions 60-525.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-7209N.
IntAct	P47185. 1 interaction.
MINT	MINT-1365148.
STRING	4932.YJR158W.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YJR158W; YJR158W; YJR158W.
GeneID	853623.
KEGG	sce:YJR158W.
Organism-specific databases
CYGD	YJR158w.
SGD	S000003919. HXT16.
Phylogenomic databases
GeneTree	ENSGT00650000093295.
HOGENOM	HOG000202870.
KO	K08139.
OrthoDB	EOG43246F.
Gene expression databases
Genevestigator	P47185.
GermOnline	YJR158W. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR020846. MFS_dom. IPR016196. MFS_dom_general_subst_transpt. IPR005828. Sub_transporter. IPR003663. Sugar/inositol_transpt. IPR005829. Sugar_transporter_CS. [Graphical view]
Pfam	PF00083. Sugar_tr. 1 hit. [Graphical view]
PRINTS	PR00171. SUGRTRNSPORT.
SUPFAM	SSF103473. MFS_gen_substrate_transporter. 1 hit.
TIGRFAMs	TIGR00879. SP. 1 hit.
PROSITE	PS50850. MFS. 1 hit. PS00216. SUGAR_TRANSPORT_1. 1 hit. PS00217. SUGAR_TRANSPORT_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	974487.

Entry information

Entry name

HXT16_YEAST

Accession

Primary (citable) accession number: P47185
Secondary accession number(s): D6VWX6

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1996
Last sequence update:	February 1, 1996
Last modified:	May 1, 2013
This is version 90 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program

Relevant documents

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

Yeast chromosome X

Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

SIMILARITY comments

Index of protein domains and families

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Molecule processing

Regions

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

Other

Entry information

Relevant documents