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P47185

- HXT16_YEAST

UniProt

P47185 - HXT16_YEAST

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Protein

Hexose transporter HXT16

Gene

HXT16

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 4 out of 5- Protein inferred from homologyi

Functioni

Probable glucose transporter.

GO - Molecular functioni

  1. fructose transmembrane transporter activity Source: SGD
  2. glucose transmembrane transporter activity Source: SGD
  3. mannose transmembrane transporter activity Source: SGD

GO - Biological processi

  1. fructose transport Source: GOC
  2. glucose transport Source: GOC
  3. hexose transport Source: SGD
  4. mannose transport Source: GOC
Complete GO annotation...

Keywords - Biological processi

Sugar transport, Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-31768-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Hexose transporter HXT16
Gene namesi
Name:HXT16
Ordered Locus Names:YJR158W
ORF Names:J2260
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome X

Organism-specific databases

CYGDiYJR158w.
SGDiS000003919. HXT16.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 567567Hexose transporter HXT16PRO_0000050405Add
BLAST

Expressioni

Gene expression databases

GenevestigatoriP47185.

Interactioni

Protein-protein interaction databases

BioGridi33912. 23 interactions.
DIPiDIP-7209N.
IntActiP47185. 2 interactions.
MINTiMINT-1365148.
STRINGi4932.YJR158W.

Structurei

3D structure databases

ProteinModelPortaliP47185.
SMRiP47185. Positions 60-525.
ModBaseiSearch...
MobiDBiSearch...

Topological domain

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 5555CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini77 – 11236ExtracellularSequence AnalysisAdd
BLAST
Topological domaini134 – 1396CytoplasmicSequence Analysis
Topological domaini161 – 17010ExtracellularSequence Analysis
Topological domaini192 – 1976CytoplasmicSequence Analysis
Topological domaini219 – 23214ExtracellularSequence AnalysisAdd
BLAST
Topological domaini254 – 33683CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini354 – 3596ExtracellularSequence Analysis
Topological domaini378 – 3847CytoplasmicSequence Analysis
Topological domaini406 – 42722ExtracellularSequence AnalysisAdd
BLAST
Topological domaini449 – 46517CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini487 – 4871ExtracellularSequence Analysis
Topological domaini509 – 56759CytoplasmicSequence AnalysisAdd
BLAST

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei56 – 7621Helical; Name=1Sequence AnalysisAdd
BLAST
Transmembranei113 – 13321Helical; Name=2Sequence AnalysisAdd
BLAST
Transmembranei140 – 16021Helical; Name=3Sequence AnalysisAdd
BLAST
Transmembranei171 – 19121Helical; Name=4Sequence AnalysisAdd
BLAST
Transmembranei198 – 21821Helical; Name=5Sequence AnalysisAdd
BLAST
Transmembranei233 – 25321Helical; Name=6Sequence AnalysisAdd
BLAST
Transmembranei337 – 35317Helical; Name=7Sequence AnalysisAdd
BLAST
Transmembranei360 – 37718Helical; Name=8Sequence AnalysisAdd
BLAST
Transmembranei385 – 40521Helical; Name=9Sequence AnalysisAdd
BLAST
Transmembranei428 – 44821Helical; Name=10Sequence AnalysisAdd
BLAST
Transmembranei466 – 48621Helical; Name=11Sequence AnalysisAdd
BLAST
Transmembranei488 – 50821Helical; Name=12Sequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00720000108754.
HOGENOMiHOG000202870.
InParanoidiP47185.
KOiK08139.
OMAiCLIWIFK.
OrthoDBiEOG73JM4H.

Family and domain databases

InterProiIPR020846. MFS_dom.
IPR016196. MFS_dom_general_subst_transpt.
IPR005828. Sub_transporter.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 2 hits.
TIGRFAMsiTIGR00879. SP. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P47185-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MASEQSSPEI NADNLNSSAA DVHVQPPGEK EWSDGFYDKE VINGNTPDAP
60 70 80 90 100
KRGFLGYLII YLLCYPVSFG GFLPGWDSGI TAGFINMDNF KMNFGSYKHS
110 120 130 140 150
TGEYYLSNVR MGLLVAMFSV GCSIGGVAFA RLADTLGRRL AIVIVVLVYM
160 170 180 190 200
VGAIIQISSN HKWYQYFVGK IIYGLGAGGC SVLCPMLLSE IAPTDLRGGL
210 220 230 240 250
VSLYQLNMTF GIFLGYCSVY GTRKYSNTAQ WRIPVGLCFL WALIIIVGML
260 270 280 290 300
LVPESPRYLI ECERHEEACV SIAKIDKVSP EDPWVLKQAD EINAGVLAQR
310 320 330 340 350
ELGEASWKEL FSVKTKVLQR LITGILVQTF LQLTGENYFF FYGTTIFKSV
360 370 380 390 400
GLTDGFETSI VLGTVNFFST IIAVMVVDKI GRRKCLLFGA ASMMACMVIF
410 420 430 440 450
ASIGVKCLYP HGQDGPSSKG AGNAMIVFTC FYIFCFATTW APVAYIVVAE
460 470 480 490 500
SFPSKVKSKA MSISTAFNWL WQFLIGFFTP FITGSIHFYY GYVFVGCLVA
510 520 530 540 550
MFLYVFFFLP ETIGLSLEET QLLYEEGIKP WKSASWVPPS RRGASSRETE
560
AKKKSWKEVL KFPKSFN
Length:567
Mass (Da):62,920
Last modified:February 1, 1996 - v1
Checksum:iB9C3C21B97528A4D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z49658 Genomic DNA. Translation: CAA89691.1.
BK006943 Genomic DNA. Translation: DAA08942.1.
PIRiS57187.
RefSeqiNP_012692.3. NM_001181816.3.

Genome annotation databases

EnsemblFungiiYJR158W; YJR158W; YJR158W.
GeneIDi853623.
KEGGisce:YJR158W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z49658 Genomic DNA. Translation: CAA89691.1 .
BK006943 Genomic DNA. Translation: DAA08942.1 .
PIRi S57187.
RefSeqi NP_012692.3. NM_001181816.3.

3D structure databases

ProteinModelPortali P47185.
SMRi P47185. Positions 60-525.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 33912. 23 interactions.
DIPi DIP-7209N.
IntActi P47185. 2 interactions.
MINTi MINT-1365148.
STRINGi 4932.YJR158W.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YJR158W ; YJR158W ; YJR158W .
GeneIDi 853623.
KEGGi sce:YJR158W.

Organism-specific databases

CYGDi YJR158w.
SGDi S000003919. HXT16.

Phylogenomic databases

GeneTreei ENSGT00720000108754.
HOGENOMi HOG000202870.
InParanoidi P47185.
KOi K08139.
OMAi CLIWIFK.
OrthoDBi EOG73JM4H.

Enzyme and pathway databases

BioCyci YEAST:G3O-31768-MONOMER.

Miscellaneous databases

NextBioi 974487.

Gene expression databases

Genevestigatori P47185.

Family and domain databases

InterProi IPR020846. MFS_dom.
IPR016196. MFS_dom_general_subst_transpt.
IPR005828. Sub_transporter.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view ]
Pfami PF00083. Sugar_tr. 1 hit.
[Graphical view ]
PRINTSi PR00171. SUGRTRNSPORT.
SUPFAMi SSF103473. SSF103473. 2 hits.
TIGRFAMsi TIGR00879. SP. 1 hit.
PROSITEi PS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."
    Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K.
    , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.
    EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.

Entry informationi

Entry nameiHXT16_YEAST
AccessioniPrimary (citable) accession number: P47185
Secondary accession number(s): D6VWX6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: October 29, 2014
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome X
    Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

External Data

Dasty 3