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P47185 (HXT16_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 99. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Hexose transporter HXT16
Gene names
Name:HXT16
Ordered Locus Names:YJR158W
ORF Names:J2260
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length567 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Probable glucose transporter.

Subcellular location

Membrane; Multi-pass membrane protein Potential.

Sequence similarities

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 567567Hexose transporter HXT16
PRO_0000050405

Regions

Topological domain1 – 5555Cytoplasmic Potential
Transmembrane56 – 7621Helical; Name=1; Potential
Topological domain77 – 11236Extracellular Potential
Transmembrane113 – 13321Helical; Name=2; Potential
Topological domain134 – 1396Cytoplasmic Potential
Transmembrane140 – 16021Helical; Name=3; Potential
Topological domain161 – 17010Extracellular Potential
Transmembrane171 – 19121Helical; Name=4; Potential
Topological domain192 – 1976Cytoplasmic Potential
Transmembrane198 – 21821Helical; Name=5; Potential
Topological domain219 – 23214Extracellular Potential
Transmembrane233 – 25321Helical; Name=6; Potential
Topological domain254 – 33683Cytoplasmic Potential
Transmembrane337 – 35317Helical; Name=7; Potential
Topological domain354 – 3596Extracellular Potential
Transmembrane360 – 37718Helical; Name=8; Potential
Topological domain378 – 3847Cytoplasmic Potential
Transmembrane385 – 40521Helical; Name=9; Potential
Topological domain406 – 42722Extracellular Potential
Transmembrane428 – 44821Helical; Name=10; Potential
Topological domain449 – 46517Cytoplasmic Potential
Transmembrane466 – 48621Helical; Name=11; Potential
Topological domain4871Extracellular Potential
Transmembrane488 – 50821Helical; Name=12; Potential
Topological domain509 – 56759Cytoplasmic Potential

Sequences

Sequence LengthMass (Da)Tools
P47185 [UniParc].

Last modified February 1, 1996. Version 1.
Checksum: B9C3C21B97528A4D

FASTA56762,920
        10         20         30         40         50         60 
MASEQSSPEI NADNLNSSAA DVHVQPPGEK EWSDGFYDKE VINGNTPDAP KRGFLGYLII 

        70         80         90        100        110        120 
YLLCYPVSFG GFLPGWDSGI TAGFINMDNF KMNFGSYKHS TGEYYLSNVR MGLLVAMFSV 

       130        140        150        160        170        180 
GCSIGGVAFA RLADTLGRRL AIVIVVLVYM VGAIIQISSN HKWYQYFVGK IIYGLGAGGC 

       190        200        210        220        230        240 
SVLCPMLLSE IAPTDLRGGL VSLYQLNMTF GIFLGYCSVY GTRKYSNTAQ WRIPVGLCFL 

       250        260        270        280        290        300 
WALIIIVGML LVPESPRYLI ECERHEEACV SIAKIDKVSP EDPWVLKQAD EINAGVLAQR 

       310        320        330        340        350        360 
ELGEASWKEL FSVKTKVLQR LITGILVQTF LQLTGENYFF FYGTTIFKSV GLTDGFETSI 

       370        380        390        400        410        420 
VLGTVNFFST IIAVMVVDKI GRRKCLLFGA ASMMACMVIF ASIGVKCLYP HGQDGPSSKG 

       430        440        450        460        470        480 
AGNAMIVFTC FYIFCFATTW APVAYIVVAE SFPSKVKSKA MSISTAFNWL WQFLIGFFTP 

       490        500        510        520        530        540 
FITGSIHFYY GYVFVGCLVA MFLYVFFFLP ETIGLSLEET QLLYEEGIKP WKSASWVPPS 

       550        560 
RRGASSRETE AKKKSWKEVL KFPKSFN 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z49658 Genomic DNA. Translation: CAA89691.1.
BK006943 Genomic DNA. Translation: DAA08942.1.
PIRS57187.
RefSeqNP_012692.3. NM_001181816.3.

3D structure databases

ProteinModelPortalP47185.
SMRP47185. Positions 63-514.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid33912. 23 interactions.
DIPDIP-7209N.
IntActP47185. 2 interactions.
MINTMINT-1365148.
STRING4932.YJR158W.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYJR158W; YJR158W; YJR158W.
GeneID853623.
KEGGsce:YJR158W.

Organism-specific databases

CYGDYJR158w.
SGDS000003919. HXT16.

Phylogenomic databases

GeneTreeENSGT00720000108754.
HOGENOMHOG000202870.
KOK08139.
OrthoDBEOG73JM4H.

Enzyme and pathway databases

BioCycYEAST:G3O-31768-MONOMER.

Gene expression databases

GenevestigatorP47185.

Family and domain databases

InterProIPR020846. MFS_dom.
IPR016196. MFS_dom_general_subst_transpt.
IPR005828. Sub_transporter.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamPF00083. Sugar_tr. 1 hit.
[Graphical view]
PRINTSPR00171. SUGRTRNSPORT.
SUPFAMSSF103473. SSF103473. 2 hits.
TIGRFAMsTIGR00879. SP. 1 hit.
PROSITEPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio974487.

Entry information

Entry nameHXT16_YEAST
AccessionPrimary (citable) accession number: P47185
Secondary accession number(s): D6VWX6
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: April 16, 2014
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome X

Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families