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P47185

- HXT16_YEAST

UniProt

P47185 - HXT16_YEAST

Protein

Hexose transporter HXT16

Gene

HXT16

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 4 out of 5- Protein inferred from homologyi
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    • History
      Entry version 102 (01 Oct 2014)
      Sequence version 1 (01 Feb 1996)
      Previous versions | rss
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    Functioni

    Probable glucose transporter.

    GO - Molecular functioni

    1. fructose transmembrane transporter activity Source: SGD
    2. glucose transmembrane transporter activity Source: SGD
    3. mannose transmembrane transporter activity Source: SGD

    GO - Biological processi

    1. fructose transport Source: GOC
    2. glucose transport Source: GOC
    3. hexose transport Source: SGD
    4. mannose transport Source: GOC

    Keywords - Biological processi

    Sugar transport, Transport

    Enzyme and pathway databases

    BioCyciYEAST:G3O-31768-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Hexose transporter HXT16
    Gene namesi
    Name:HXT16
    Ordered Locus Names:YJR158W
    ORF Names:J2260
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome X

    Organism-specific databases

    CYGDiYJR158w.
    SGDiS000003919. HXT16.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: SGD

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 567567Hexose transporter HXT16PRO_0000050405Add
    BLAST

    Expressioni

    Gene expression databases

    GenevestigatoriP47185.

    Interactioni

    Protein-protein interaction databases

    BioGridi33912. 23 interactions.
    DIPiDIP-7209N.
    IntActiP47185. 2 interactions.
    MINTiMINT-1365148.
    STRINGi4932.YJR158W.

    Structurei

    3D structure databases

    ProteinModelPortaliP47185.
    SMRiP47185. Positions 60-525.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 5555CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini77 – 11236ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini134 – 1396CytoplasmicSequence Analysis
    Topological domaini161 – 17010ExtracellularSequence Analysis
    Topological domaini192 – 1976CytoplasmicSequence Analysis
    Topological domaini219 – 23214ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini254 – 33683CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini354 – 3596ExtracellularSequence Analysis
    Topological domaini378 – 3847CytoplasmicSequence Analysis
    Topological domaini406 – 42722ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini449 – 46517CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini487 – 4871ExtracellularSequence Analysis
    Topological domaini509 – 56759CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei56 – 7621Helical; Name=1Sequence AnalysisAdd
    BLAST
    Transmembranei113 – 13321Helical; Name=2Sequence AnalysisAdd
    BLAST
    Transmembranei140 – 16021Helical; Name=3Sequence AnalysisAdd
    BLAST
    Transmembranei171 – 19121Helical; Name=4Sequence AnalysisAdd
    BLAST
    Transmembranei198 – 21821Helical; Name=5Sequence AnalysisAdd
    BLAST
    Transmembranei233 – 25321Helical; Name=6Sequence AnalysisAdd
    BLAST
    Transmembranei337 – 35317Helical; Name=7Sequence AnalysisAdd
    BLAST
    Transmembranei360 – 37718Helical; Name=8Sequence AnalysisAdd
    BLAST
    Transmembranei385 – 40521Helical; Name=9Sequence AnalysisAdd
    BLAST
    Transmembranei428 – 44821Helical; Name=10Sequence AnalysisAdd
    BLAST
    Transmembranei466 – 48621Helical; Name=11Sequence AnalysisAdd
    BLAST
    Transmembranei488 – 50821Helical; Name=12Sequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Repeat, Transmembrane, Transmembrane helix

    Phylogenomic databases

    GeneTreeiENSGT00720000108754.
    HOGENOMiHOG000202870.
    KOiK08139.
    OMAiCLIWIFK.
    OrthoDBiEOG73JM4H.

    Family and domain databases

    InterProiIPR020846. MFS_dom.
    IPR016196. MFS_dom_general_subst_transpt.
    IPR005828. Sub_transporter.
    IPR003663. Sugar/inositol_transpt.
    IPR005829. Sugar_transporter_CS.
    [Graphical view]
    PfamiPF00083. Sugar_tr. 1 hit.
    [Graphical view]
    PRINTSiPR00171. SUGRTRNSPORT.
    SUPFAMiSSF103473. SSF103473. 2 hits.
    TIGRFAMsiTIGR00879. SP. 1 hit.
    PROSITEiPS50850. MFS. 1 hit.
    PS00216. SUGAR_TRANSPORT_1. 1 hit.
    PS00217. SUGAR_TRANSPORT_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P47185-1 [UniParc]FASTAAdd to Basket

    « Hide

    MASEQSSPEI NADNLNSSAA DVHVQPPGEK EWSDGFYDKE VINGNTPDAP    50
    KRGFLGYLII YLLCYPVSFG GFLPGWDSGI TAGFINMDNF KMNFGSYKHS 100
    TGEYYLSNVR MGLLVAMFSV GCSIGGVAFA RLADTLGRRL AIVIVVLVYM 150
    VGAIIQISSN HKWYQYFVGK IIYGLGAGGC SVLCPMLLSE IAPTDLRGGL 200
    VSLYQLNMTF GIFLGYCSVY GTRKYSNTAQ WRIPVGLCFL WALIIIVGML 250
    LVPESPRYLI ECERHEEACV SIAKIDKVSP EDPWVLKQAD EINAGVLAQR 300
    ELGEASWKEL FSVKTKVLQR LITGILVQTF LQLTGENYFF FYGTTIFKSV 350
    GLTDGFETSI VLGTVNFFST IIAVMVVDKI GRRKCLLFGA ASMMACMVIF 400
    ASIGVKCLYP HGQDGPSSKG AGNAMIVFTC FYIFCFATTW APVAYIVVAE 450
    SFPSKVKSKA MSISTAFNWL WQFLIGFFTP FITGSIHFYY GYVFVGCLVA 500
    MFLYVFFFLP ETIGLSLEET QLLYEEGIKP WKSASWVPPS RRGASSRETE 550
    AKKKSWKEVL KFPKSFN 567
    Length:567
    Mass (Da):62,920
    Last modified:February 1, 1996 - v1
    Checksum:iB9C3C21B97528A4D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z49658 Genomic DNA. Translation: CAA89691.1.
    BK006943 Genomic DNA. Translation: DAA08942.1.
    PIRiS57187.
    RefSeqiNP_012692.3. NM_001181816.3.

    Genome annotation databases

    EnsemblFungiiYJR158W; YJR158W; YJR158W.
    GeneIDi853623.
    KEGGisce:YJR158W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z49658 Genomic DNA. Translation: CAA89691.1 .
    BK006943 Genomic DNA. Translation: DAA08942.1 .
    PIRi S57187.
    RefSeqi NP_012692.3. NM_001181816.3.

    3D structure databases

    ProteinModelPortali P47185.
    SMRi P47185. Positions 60-525.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 33912. 23 interactions.
    DIPi DIP-7209N.
    IntActi P47185. 2 interactions.
    MINTi MINT-1365148.
    STRINGi 4932.YJR158W.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YJR158W ; YJR158W ; YJR158W .
    GeneIDi 853623.
    KEGGi sce:YJR158W.

    Organism-specific databases

    CYGDi YJR158w.
    SGDi S000003919. HXT16.

    Phylogenomic databases

    GeneTreei ENSGT00720000108754.
    HOGENOMi HOG000202870.
    KOi K08139.
    OMAi CLIWIFK.
    OrthoDBi EOG73JM4H.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-31768-MONOMER.

    Miscellaneous databases

    NextBioi 974487.

    Gene expression databases

    Genevestigatori P47185.

    Family and domain databases

    InterProi IPR020846. MFS_dom.
    IPR016196. MFS_dom_general_subst_transpt.
    IPR005828. Sub_transporter.
    IPR003663. Sugar/inositol_transpt.
    IPR005829. Sugar_transporter_CS.
    [Graphical view ]
    Pfami PF00083. Sugar_tr. 1 hit.
    [Graphical view ]
    PRINTSi PR00171. SUGRTRNSPORT.
    SUPFAMi SSF103473. SSF103473. 2 hits.
    TIGRFAMsi TIGR00879. SP. 1 hit.
    PROSITEi PS50850. MFS. 1 hit.
    PS00216. SUGAR_TRANSPORT_1. 1 hit.
    PS00217. SUGAR_TRANSPORT_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."
      Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K.
      , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.
      EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.

    Entry informationi

    Entry nameiHXT16_YEAST
    AccessioniPrimary (citable) accession number: P47185
    Secondary accession number(s): D6VWX6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1996
    Last sequence update: February 1, 1996
    Last modified: October 1, 2014
    This is version 102 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    3. Yeast chromosome X
      Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

    External Data

    Dasty 3