Reviewed, UniProtKB/Swiss-Prot P47182 (AAD10_YEAST)

Names and origin

Protein names

Recommended name:
    Putative aryl-alcohol dehydrogenase AAD10
    EC=1.1.1.-

Gene names

Name:	AAD10
Ordered Locus Names:	YJR155W
ORF Names:	J2245

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	288 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Sequence similarities

Belongs to the aldo/keto reductase 2 family.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW response to toxin Inferred from expression pattern. Source: SGD
Molecular function	oxidoreductase activity Inferred from electronic annotation. Source: UniProtKB-KW protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
TAF2	P23255	1	EBI-2042675,EBI-18862

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 288	288	Putative aryl-alcohol dehydrogenase AAD10		PRO_0000070368

Sequences

	Sequence		Length	Mass (Da)
	P47182-1 [UniParc]. Last modified February 1, 1996. Version 1. Checksum: 4E963216BE0600E2	FASTA	288	32,570
	10 20 30 40 50 60 MASRKLRDQI VIATKFTTDY KGYDVGKGKS ANFCGNHKRS LHVSVRDSLR KLQTDWIDIL 70 80 90 100 110 120 YVHWWDYMSS IEEVMDSLHI LVQQGKVLYL GVSDTPAWVV SAANYYATSH GKTPFSIYQG 130 140 150 160 170 180 KWNVLNRDFE RDIIPMARHF GMALAPWDVM GGGRFQSKKA VEERKKKGEG LRTFFGTSEQ 190 200 210 220 230 240 TDMEVKISEA LLKVAEEHGT ESVTAIAIAY VRSKAKHVFP LVGGRKIEHL KQNIEALSIK 250 260 270 280 LTPEQIKYLE SIVPFDVGFP TNFIGDDPAV TKKPSFLTEM SAKISFED

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X." Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K. , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L. EMBO J. 15:2031-2049(1996) [PubMed: 8641269] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679.
[2]	"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J. Genome Res. 17:536-543(2007) [PubMed: 17322287] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	Z49655 Genomic DNA. Translation: CAA89688.1. AY557908 Genomic DNA. Translation: AAS56234.1.
PIR	S57184.
RefSeq	NP_012689.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	P47182. 1 interaction.
STRING	P47182.
Genome annotation databases
Ensembl	YJR155W; YJR155W; YJR155W; Saccharomyces cerevisiae. [Genome view]
GeneID	853620.
KEGG	sce:YJR155W.
NMPDR	fig|4932.3.peg.3667.
Organism-specific databases
CYGD	YJR155w.
SGD	S000003916. AAD10.
Phylogenomic databases
HOGENOM	HBG605727.
OMA	HIREEDI.
OrthoDB	EOG9G7DGX.
Gene expression databases
ArrayExpress	P47182.
Genevestigator	P47182.
GermOnline	YJR155W. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR001395. Aldo/ket_red. [Graphical view]
Gene3D	G3DSA:3.20.20.100. Aldo/ket_red. 1 hit.
PANTHER	PTHR11732. Aldo/ket_red. 1 hit.
Pfam	PF00248. Aldo_ket_red. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	974481.

Entry information

Entry name

AAD10_YEAST

Accession

Primary (citable) accession number: P47182

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1996
Last sequence update:	February 1, 1996
Last modified:	December 15, 2009
This is version 64 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)