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Protein

Probable transcription factor HMS2

Gene

HMS2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in pseudohyphal differentiation.1 Publication

Miscellaneous

Present with 2050 molecules/cell in log phase SD medium.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi12 – 116By similarityAdd BLAST105

GO - Molecular functioni

GO - Biological processi

  • pseudohyphal growth Source: SGD

Keywordsi

Molecular functionDNA-binding

Enzyme and pathway databases

BioCyciYEAST:G3O-31761-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Probable transcription factor HMS2
Alternative name(s):
High-copy MEP suppressor 2
Gene namesi
Name:HMS2
Ordered Locus Names:YJR147W
ORF Names:J2204
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome X

Organism-specific databases

EuPathDBiFungiDB:YJR147W
SGDiS000003908 HMS2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001245961 – 358Probable transcription factor HMS2Add BLAST358

Proteomic databases

MaxQBiP47175
PaxDbiP47175
PRIDEiP47175

Interactioni

Protein-protein interaction databases

BioGridi33902, 115 interactors
IntActiP47175, 2 interactors
STRINGi4932.YJR147W

Structurei

3D structure databases

ProteinModelPortaliP47175
SMRiP47175
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the HSF family.Curated

Phylogenomic databases

GeneTreeiENSGT00610000087034
InParanoidiP47175
OrthoDBiEOG092C2WRR

Family and domain databases

Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR000232 HSF_DNA-bd
IPR027725 HSF_fam
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PANTHERiPTHR10015 PTHR10015, 1 hit
PfamiView protein in Pfam
PF00447 HSF_DNA-bind, 1 hit
PRINTSiPR00056 HSFDOMAIN
SMARTiView protein in SMART
SM00415 HSF, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit

Sequencei

Sequence statusi: Complete.

P47175-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDATSRMEQP DVFVSKLYHL LQGNAYSNII QWSTDGSKLV IWNPDQFTKV
60 70 80 90 100
ILERFFGIHT FAAFVKQLSK YNFQKAGRPD CVEFSNIHFQ KDNINSLSLV
110 120 130 140 150
KAHQSAATPN VAAVNNMNKQ CTFHWDPFKV NSILSKAIGK PSFEKLVKNV
160 170 180 190 200
DRLQGNLDEL KSTNADSLRI IREINASLQT ISYHQFHAYQ TANFLQENFE
210 220 230 240 250
AIKKVVCPDS CLQHQQRQPK RPKRYSLLLL IPNASELSET PLMRFAGVFE
260 270 280 290 300
FMNCSLDTAT QWHPQLHPEA YDLLFVTVSP NMQQEHLIYF KRLRNLLPSF
310 320 330 340 350
PVIAIINRPV SPQDTSIAPS NYSRYYFHHF LQLGFSDILV SPFTPTQLIT

LLSKHLRT
Length:358
Mass (Da):41,192
Last modified:February 1, 1996 - v1
Checksum:iE2964157FC952D42
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49646 Genomic DNA Translation: CAA89680.1
BK006943 Genomic DNA Translation: DAA08931.1
PIRiS57176
RefSeqiNP_012681.1, NM_001181805.1

Genome annotation databases

EnsemblFungiiYJR147W; YJR147W; YJR147W
GeneIDi853612
KEGGisce:YJR147W

Similar proteinsi

Entry informationi

Entry nameiHMS2_YEAST
AccessioniPrimary (citable) accession number: P47175
Secondary accession number(s): D6VWW5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: March 28, 2018
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health