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Protein

Probable transcription factor HMS2

Gene

HMS2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Involved in pseudohyphal differentiation.1 Publication

Miscellaneous

Present with 2050 molecules/cell in log phase SD medium.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi12 – 116By similarityAdd BLAST105

GO - Molecular functioni

GO - Biological processi

  • pseudohyphal growth Source: SGD

Keywordsi

Molecular functionDNA-binding

Enzyme and pathway databases

BioCyciYEAST:G3O-31761-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable transcription factor HMS2
Alternative name(s):
High-copy MEP suppressor 2
Gene namesi
Name:HMS2
Ordered Locus Names:YJR147W
ORF Names:J2204
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome X

Organism-specific databases

EuPathDBiFungiDB:YJR147W.
SGDiS000003908. HMS2.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001245961 – 358Probable transcription factor HMS2Add BLAST358

Proteomic databases

MaxQBiP47175.
PRIDEiP47175.

Interactioni

Protein-protein interaction databases

BioGridi33902. 115 interactors.
MINTiMINT-4492196.
STRINGi4932.YJR147W.

Structurei

3D structure databases

ProteinModelPortaliP47175.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the HSF family.Curated

Phylogenomic databases

GeneTreeiENSGT00610000087034.
InParanoidiP47175.
OrthoDBiEOG092C2WRR.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR000232. HSF_DNA-bd.
IPR027725. HSF_fam.
IPR036388. WH-like_DNA-bd_sf.
IPR036390. WH_DNA-bd_sf.
PANTHERiPTHR10015. PTHR10015. 1 hit.
PfamiView protein in Pfam
PF00447. HSF_DNA-bind. 1 hit.
PRINTSiPR00056. HSFDOMAIN.
SMARTiView protein in SMART
SM00415. HSF. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.

Sequencei

Sequence statusi: Complete.

P47175-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDATSRMEQP DVFVSKLYHL LQGNAYSNII QWSTDGSKLV IWNPDQFTKV
60 70 80 90 100
ILERFFGIHT FAAFVKQLSK YNFQKAGRPD CVEFSNIHFQ KDNINSLSLV
110 120 130 140 150
KAHQSAATPN VAAVNNMNKQ CTFHWDPFKV NSILSKAIGK PSFEKLVKNV
160 170 180 190 200
DRLQGNLDEL KSTNADSLRI IREINASLQT ISYHQFHAYQ TANFLQENFE
210 220 230 240 250
AIKKVVCPDS CLQHQQRQPK RPKRYSLLLL IPNASELSET PLMRFAGVFE
260 270 280 290 300
FMNCSLDTAT QWHPQLHPEA YDLLFVTVSP NMQQEHLIYF KRLRNLLPSF
310 320 330 340 350
PVIAIINRPV SPQDTSIAPS NYSRYYFHHF LQLGFSDILV SPFTPTQLIT

LLSKHLRT
Length:358
Mass (Da):41,192
Last modified:February 1, 1996 - v1
Checksum:iE2964157FC952D42
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49646 Genomic DNA. Translation: CAA89680.1.
BK006943 Genomic DNA. Translation: DAA08931.1.
PIRiS57176.
RefSeqiNP_012681.1. NM_001181805.1.

Genome annotation databases

EnsemblFungiiYJR147W; YJR147W; YJR147W.
GeneIDi853612.
KEGGisce:YJR147W.

Similar proteinsi

Entry informationi

Entry nameiHMS2_YEAST
AccessioniPrimary (citable) accession number: P47175
Secondary accession number(s): D6VWW5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: November 22, 2017
This is version 116 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome X
    Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names