ID   YJ9I_YEAST              Reviewed;         347 AA.
AC   P47172; D6VWW0;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 1.
DT   24-JAN-2024, entry version 137.
DE   RecName: Full=Uncharacterized protein YJR141W;
GN   OrderedLocusNames=YJR141W; ORFNames=J2166;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=8641269; DOI=10.1002/j.1460-2075.1996.tb00557.x;
RA   Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C.,
RA   Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D.,
RA   Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J.,
RA   Heumann K., Hilger F., Hollenberg C.P., Huang M.-E., Jacq C.,
RA   Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E.,
RA   Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T.,
RA   Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B.,
RA   Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R.,
RA   Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N.,
RA   To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H.,
RA   von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.;
RT   "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X.";
RL   EMBO J. 15:2031-2049(1996).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=17322287; DOI=10.1101/gr.6037607;
RA   Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA   Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA   Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA   Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA   LaBaer J.;
RT   "Approaching a complete repository of sequence-verified protein-encoding
RT   clones for Saccharomyces cerevisiae.";
RL   Genome Res. 17:536-543(2007).
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DR   EMBL; Z49641; CAA89673.1; -; Genomic_DNA.
DR   EMBL; AY558090; AAS56416.1; -; Genomic_DNA.
DR   EMBL; BK006943; DAA08926.1; -; Genomic_DNA.
DR   PIR; S57164; S57164.
DR   RefSeq; NP_012675.1; NM_001181799.1.
DR   AlphaFoldDB; P47172; -.
DR   BioGRID; 33897; 339.
DR   DIP; DIP-4477N; -.
DR   IntAct; P47172; 6.
DR   STRING; 4932.YJR141W; -.
DR   MaxQB; P47172; -.
DR   PaxDb; 4932-YJR141W; -.
DR   PeptideAtlas; P47172; -.
DR   TopDownProteomics; P47172; -.
DR   EnsemblFungi; YJR141W_mRNA; YJR141W; YJR141W.
DR   GeneID; 853606; -.
DR   KEGG; sce:YJR141W; -.
DR   AGR; SGD:S000003902; -.
DR   SGD; S000003902; YJR141W.
DR   VEuPathDB; FungiDB:YJR141W; -.
DR   eggNOG; KOG4784; Eukaryota.
DR   HOGENOM; CLU_029122_0_0_1; -.
DR   InParanoid; P47172; -.
DR   OMA; QAMKVFY; -.
DR   OrthoDB; 1430320at2759; -.
DR   BioCyc; YEAST:G3O-31756-MONOMER; -.
DR   Reactome; R-SCE-983168; Antigen processing: Ubiquitination & Proteasome degradation.
DR   BioGRID-ORCS; 853606; 4 hits in 10 CRISPR screens.
DR   PRO; PR:P47172; -.
DR   Proteomes; UP000002311; Chromosome X.
DR   RNAct; P47172; Protein.
DR   GO; GO:0005829; C:cytosol; IDA:SGD.
DR   GO; GO:0005634; C:nucleus; IDA:SGD.
DR   GO; GO:0000151; C:ubiquitin ligase complex; IBA:GO_Central.
DR   GO; GO:0030332; F:cyclin binding; IBA:GO_Central.
DR   GO; GO:0031624; F:ubiquitin conjugating enzyme binding; IPI:SGD.
DR   GO; GO:0061630; F:ubiquitin protein ligase activity; IBA:GO_Central.
DR   GO; GO:0031397; P:negative regulation of protein ubiquitination; IMP:SGD.
DR   GO; GO:0031442; P:positive regulation of mRNA 3'-end processing; IMP:SGD.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IMP:SGD.
DR   GO; GO:0051865; P:protein autoubiquitination; IBA:GO_Central.
DR   GO; GO:0006513; P:protein monoubiquitination; IBA:GO_Central.
DR   GO; GO:0000209; P:protein polyubiquitination; IBA:GO_Central.
DR   InterPro; IPR019193; UBQ-conj_enz_E2-bd_prot.
DR   PANTHER; PTHR31531:SF2; E3 UBIQUITIN-PROTEIN LIGASE E3D; 1.
DR   PANTHER; PTHR31531; E3 UBIQUITIN-PROTEIN LIGASE E3D FAMILY MEMBER; 1.
DR   Pfam; PF09814; HECT_2; 1.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..347
FT                   /note="Uncharacterized protein YJR141W"
FT                   /id="PRO_0000203125"
SQ   SEQUENCE   347 AA;  39902 MW;  6FF877ECD317C971 CRC64;
     MVQYVVEWLP RIQSISVVVE GWKQVEIKNL KDTLMSISGD EEQVEDILLP VEVEEKVDAS
     YKFKNRGKDL EWMTKLRSKS SKIYDSSIMS LPDGRWTKEE LRSDSDFSIE CLNCKQKIIS
     KDNCQVLNDM PSEFWFELMD YWHCHKPDVK EDKSSYTRFE TLKPSKNEIL IGSSYFQGTP
     ATFENVATTK ENDNVLCIKC SAVLGQVTAG SLYKLHKWKL QLIRSGNTYK FPPECDITIS
     LINVVKANSC RYVLVKCKTE SLLVWIFSVD IGVTLTGNKS FKRAMKLLYT NSVTTINRCL
     NRQVVEELDF QETSFNAFYS ALQHTNALLP SSMKKIGEWT ISYTSLI
//