Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

TEL2-interacting protein 2

Gene

TTI2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Component of the ASTRA complex probably in chromatin remodeling.

Miscellaneous

Present with 1470 molecules/cell in log phase SD medium.1 Publication

GO - Biological processi

  • cellular response to DNA damage stimulus Source: SGD
  • cellular response to heat Source: SGD
  • cellular response to nutrient levels Source: SGD
  • cellular response to salt stress Source: SGD
  • chromatin organization Source: UniProtKB-KW

Keywordsi

Molecular functionChromatin regulator

Enzyme and pathway databases

BioCyciYEAST:G3O-31753-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
TEL2-interacting protein 2
Gene namesi
Name:TTI2
Ordered Locus Names:YJR136C
ORF Names:J2124
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome X

Organism-specific databases

EuPathDBiFungiDB:YJR136C
SGDiS000003897 TTI2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002031221 – 421TEL2-interacting protein 2Add BLAST421

Proteomic databases

MaxQBiP47168
PaxDbiP47168
PRIDEiP47168

PTM databases

iPTMnetiP47168

Interactioni

Subunit structurei

Component of the ASTRA chromatin remodeling machinery complex composed of at least RVB1, RVB2, TRA1, TEL2, TT1 and TTI2. Component of the TTT complex composed of TEL2, TTI1 and TTI2. Interacts with TEL2 and TTI1.2 Publications

Binary interactionsi

WithEntry#Exp.IntActNotes
TTI1P360973EBI-25698,EBI-26630

Protein-protein interaction databases

BioGridi33892, 211 interactors
DIPiDIP-1913N
IntActiP47168, 9 interactors
MINTiP47168
STRINGi4932.YJR136C

Structurei

3D structure databases

ProteinModelPortaliP47168
SMRiP47168
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TTI2 family.Curated

Phylogenomic databases

HOGENOMiHOG000066090
InParanoidiP47168
OMAiWISPGIL
OrthoDBiEOG092C2AKY

Family and domain databases

InterProiView protein in InterPro
IPR018870 Tti2
PfamiView protein in Pfam
PF10521 Tti2, 1 hit

Sequencei

Sequence statusi: Complete.

P47168-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAVTDIIDE LNDSSLSSTR LRELCLQLRK KTDTGCAITV SDEVNLIESL
60 70 80 90 100
SYHSISPGVD IQINTDVLQT IDYYFQRNKS EHDEIMCVLI SKLQPLLLKR
110 120 130 140 150
KSNFELKEQR NLGLKPTLGM SLKEDNLMQA WVSQGGLKGI PLFYVILLHL
160 170 180 190 200
KRRDISTNLS WIIPGILNIL DDTTDIRRIK LRGVLLLQTL LNHTFMNETN
210 220 230 240 250
DSKWIQFSST GLFPLFEKTL INMCYFLPPS YNADETIAIW RVVFPTIQSL
260 270 280 290 300
YKVEFLDNYT KYQYHLEKFM SEIILQNIIP RASLAYENLT LYALECTMNI
310 320 330 340 350
LRLQREGSVV HLQRLIFVLG EYIVRNPFYT TFPKLISKTL SVVSTLIKVC
360 370 380 390 400
PNERIVAHRF DILSLILVTY DKCSQEDALN ESILQQCKET ISWLLNCDCA
410 420
MGEQLSTLSK QPRFQLLFEF S
Length:421
Mass (Da):48,649
Last modified:February 1, 1996 - v1
Checksum:i12042525F61D8D3F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49636 Genomic DNA Translation: CAA89668.1
AY692606 Genomic DNA Translation: AAT92625.1
BK006943 Genomic DNA Translation: DAA08921.1
PIRiS57159
RefSeqiNP_012670.3, NM_001181794.3

Genome annotation databases

EnsemblFungiiYJR136C; YJR136C; YJR136C
GeneIDi853601
KEGGisce:YJR136C

Similar proteinsi

Entry informationi

Entry nameiTTI2_YEAST
AccessioniPrimary (citable) accession number: P47168
Secondary accession number(s): D6VWV5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: May 23, 2018
This is version 126 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health