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P47166 (SGM1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 94. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein SGM1
Alternative name(s):
Slow growth on galactose and mannose protein 1
Gene names
Name:SGM1
Ordered Locus Names:YJR134C
ORF Names:J2120
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length707 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Required for normal growth rate on galactose and mannose. Ref.3

Subunit structure

Interacts with YPT6. Ref.6

Subcellular location

Golgi apparatus Ref.4.

Miscellaneous

Present with 300 molecules/cell in log phase SD medium.

Sequence similarities

Belongs to the SGM1 family.

Ontologies

Keywords
   Cellular componentGolgi apparatus
   DomainCoiled coil
   PTMAcetylation
Phosphoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentGolgi apparatus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionRab GTPase binding

Inferred from physical interaction PubMed 15128430. Source: FlyBase

Complete GO annotation...

Binary interactions

With

Entry

#Exp.

IntAct

Notes

NUP116Q026301EBI-25687,EBI-11703

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed Ref.10
Chain2 – 707706Protein SGM1
PRO_0000203121

Regions

Coiled coil122 – 473352 Potential
Coiled coil594 – 706113 Potential

Amino acid modifications

Modified residue21N-acetylserine Ref.10
Modified residue1511Phosphoserine Ref.8
Modified residue5381Phosphoserine Ref.9
Modified residue5491Phosphoserine Ref.9
Modified residue5681Phosphoserine Ref.9
Modified residue5711Phosphoserine Ref.8 Ref.9
Modified residue5761Phosphoserine Ref.9
Modified residue5891Phosphoserine Ref.8

Sequences

Sequence LengthMass (Da)Tools
P47166 [UniParc].

Last modified February 1, 1996. Version 1.
Checksum: BA47D1A7265BF3D9

FASTA70781,171
        10         20         30         40         50         60 
MSKKLSLEER LSLATKKGRK KNKRSTSNLS SPSPVVLSNN EQESARTSID DAAAGVVSID 

        70         80         90        100        110        120 
NAENIDDPAV RSESTVEGDT GKADSIAVDD VVHPDHNRTD CFDDTMVSLP TWLPKNYTEF 

       130        140        150        160        170        180 
TVEELVKEIS PEYLRLNKQI DDLTNELNRK SQIETTDSSF FKLIKEKDDL IDQLRKEGAK 

       190        200        210        220        230        240 
LAETELRQSN QIKALRTKVK DLEYEVSELN DSSAQSVENY NELQSLYHNI QGQLAEATNK 

       250        260        270        280        290        300 
LKDADKQKES LETLEKNIKE KDDLITILQQ SLDNMRTLLE KEKSEFQTEK KALQEATVDQ 

       310        320        330        340        350        360 
VTTLETKLEQ LRIELDSSTQ NLDAKSNRDF VDDQQSYEEK QHASFQYNRL KEQLESSKAN 

       370        380        390        400        410        420 
WDSIEYALNT KIVNLENRFE STMKEKNDIE EKYQTALRSS ETLGKQLEKE KENHSKAVLE 

       430        440        450        460        470        480 
VKDLERRAET LKSSLQSISD DYNLLKKKYE IQRSQLEQKE NELKPHQENS NEKIIDKIPV 

       490        500        510        520        530        540 
ELTDSLNSME GNIEDEWTLP QENSMLSLSM SKLGELESDP SLKPIYNESH ETICSEESQH 

       550        560        570        580        590        600 
FDRKNVDFSI DDIPEEAAAL QAIREGESMN SLNNTSIPYR RASVQLSNSN GHISAHLVNK 

       610        620        630        640        650        660 
LSTELKRLEG ELSASKELYD NLLKEKTKAN DEILRLLEEN DKFNEVNKQK DDLLKRVEQM 

       670        680        690        700 
QSKLETSLQL LGEKTEQVEE LENDVSDLKE MMHQQVQQMV EMQGKMR 

« Hide

References

« Hide 'large scale' references
[1]"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."
Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K. expand/collapse author list , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.
EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"Functional analysis of 150 deletion mutants in Saccharomyces cerevisiae by a systematic approach."
Entian K.-D., Schuster T., Hegemann J.H., Becher D., Feldmann H., Gueldener U., Goetz R., Hansen M., Hollenberg C.P., Jansen G., Kramer W., Klein S., Koetter P., Kricke J., Launhardt H., Mannhaupt G., Maierl A., Meyer P. expand/collapse author list , Mewes W., Munder T., Niedenthal R.K., Ramezani Rad M., Roehmer A., Roemer A., Rose M., Schaefer B., Siegler M.-L., Vetter J., Wilhelm N., Wolf K., Zimmermann F.K., Zollner A., Hinnen A.
Mol. Gen. Genet. 262:683-702(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION.
[4]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[5]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[6]"Affinity purification of Ypt6 effectors and identification of TMF/ARA160 as a Rab6 interactor."
Siniossoglou S.
Methods Enzymol. 403:599-607(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: INTERACTION WITH YPT6.
[7]"Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae."
Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J., Elias J.E., Gygi S.P.
J. Proteome Res. 6:1190-1197(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Strain: ADR376.
[8]"A multidimensional chromatography technology for in-depth phosphoproteome analysis."
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-151; SER-571 AND SER-589, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[9]"Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-538; SER-549; SER-568; SER-571 AND SER-576, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[10]"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A., Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E., Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.
Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z49634 Genomic DNA. Translation: CAA89665.1.
Z49635 Genomic DNA. Translation: CAA89667.1.
BK006943 Genomic DNA. Translation: DAA08918.1.
PIRS57157.
RefSeqNP_012668.3. NM_001181792.3.

3D structure databases

ProteinModelPortalP47166.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid33889. 62 interactions.
DIPDIP-2973N.
IntActP47166. 3 interactions.
MINTMINT-514116.
STRING4932.YJR134C.

Proteomic databases

PaxDbP47166.
PeptideAtlasP47166.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYJR134C; YJR134C; YJR134C.
GeneID853598.
KEGGsce:YJR134C.

Organism-specific databases

CYGDYJR134c.
SGDS000003895. SGM1.

Phylogenomic databases

eggNOGNOG127593.
OMAPINPARI.
OrthoDBEOG7QZGKH.

Enzyme and pathway databases

BioCycYEAST:G3O-31751-MONOMER.

Gene expression databases

GenevestigatorP47166.

Family and domain databases

InterProIPR022092. TMF_DNA-bd.
IPR022091. TMF_TATA-bd.
[Graphical view]
PfamPF12329. TMF_DNA_bd. 1 hit.
PF12325. TMF_TATA_bd. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio974418.
PROP47166.

Entry information

Entry nameSGM1_YEAST
AccessionPrimary (citable) accession number: P47166
Secondary accession number(s): D6VWV2
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: April 16, 2014
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome X

Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families