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P47159 (YJ94_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 97. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Uncharacterized membrane protein YJR124C
Gene names
Ordered Locus Names:YJR124C
ORF Names:J2046
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length448 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Membrane; Multi-pass membrane protein.

Ontologies

Keywords
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix
   LigandATP-binding
Nucleotide-binding
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtransmembrane transport

Inferred from electronic annotation. Source: InterPro

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 448448Uncharacterized membrane protein YJR124C
PRO_0000203118

Regions

Topological domain1 – 5050Extracellular Potential
Transmembrane51 – 7121Helical; Potential
Topological domain72 – 9322Cytoplasmic Potential
Transmembrane94 – 11421Helical; Potential
Topological domain115 – 14632Extracellular Potential
Transmembrane147 – 16721Helical; Potential
Topological domain168 – 18417Cytoplasmic Potential
Transmembrane185 – 20521Helical; Potential
Topological domain206 – 26055Extracellular Potential
Transmembrane261 – 28121Helical; Potential
Topological domain282 – 2876Cytoplasmic Potential
Transmembrane288 – 30821Helical; Potential
Topological domain309 – 33325Extracellular Potential
Transmembrane334 – 35421Helical; Potential
Topological domain355 – 38632Cytoplasmic Potential
Transmembrane387 – 40721Helical; Potential
Topological domain408 – 4169Extracellular Potential
Transmembrane417 – 43721Helical; Potential
Topological domain438 – 44811Cytoplasmic Potential
Nucleotide binding386 – 3938ATP Potential

Experimental info

Sequence conflict4481H → R in AAS56250. Ref.3

Sequences

Sequence LengthMass (Da)Tools
P47159 [UniParc].

Last modified February 1, 1996. Version 1.
Checksum: 2319CF9DD1220C14

FASTA44849,664
        10         20         30         40         50         60 
MAPEIFVKFK CASRDIKLLW ASVFLRLLSY GLTNQVLTLF LNAINMTEDK IGLFMSLTLA 

        70         80         90        100        110        120 
GDVICSYILT WYADSWGRRR VLVYGCAMML LSGLVFSFSE NFTLLLVFAI FGVISPSSDE 

       130        140        150        160        170        180 
VGPFKSIEEA MIAHLSPHNA RPEIYAIHAL VGTIGSALGA IICGIFVDLL KRTGLAATDL 

       190        200        210        220        230        240 
QCYKLVFLLY AFFAFCKMVI MLLLSDATEL DGHYEHTDCN EETAEPLDVN DETAPLMRQA 

       250        260        270        280        290        300 
THPEERSNKL SKETVSVLMK LLVIFMVDSL GSGFMTSGWM VYYYSKQFLM GSLALGTLFF 

       310        320        330        340        350        360 
ITQLVMASST IPSSIIARCF GPVRATLLVQ IPSGIFSILI PMAKNYLPLS ILFLNLHFAT 

       370        380        390        400        410        420 
TAMDVTPRQI LLTNIIKPRD LTKVMGVVNI GKTFARCVGP IFTGILANNN YLWLCYIISG 

       430        440 
SLVITADLIL ACMFLGVDAK IKKQMNRH 

« Hide

References

« Hide 'large scale' references
[1]"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."
Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K. expand/collapse author list , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.
EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[4]"A global topology map of the Saccharomyces cerevisiae membrane proteome."
Kim H., Melen K., Oesterberg M., von Heijne G.
Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
Strain: ATCC 208353 / W303-1A.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z49624 Genomic DNA. Translation: CAA89655.1.
AY557924 Genomic DNA. Translation: AAS56250.1.
BK006943 Genomic DNA. Translation: DAA08909.1.
PIRS57147.
RefSeqNP_012658.3. NM_001181782.3.

3D structure databases

ProteinModelPortalP47159.
SMRP47159. Positions 300-336, 379-406.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid33880. 12 interactions.
DIPDIP-7198N.
MINTMINT-2494020.
STRING4932.YJR124C.

Protein family/group databases

TCDB2.A.1.63.4. the major facilitator superfamily (mfs).

Proteomic databases

PaxDbP47159.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYJR124C; YJR124C; YJR124C.
GeneID853588.
KEGGsce:YJR124C.

Organism-specific databases

CYGDYJR124c.
SGDS000003885. YJR124C.

Phylogenomic databases

eggNOGNOG304962.
HOGENOMHOG000178084.
OMAFARCVGP.
OrthoDBEOG7V1G0X.

Enzyme and pathway databases

BioCycYEAST:G3O-31745-MONOMER.

Gene expression databases

GenevestigatorP47159.

Family and domain databases

InterProIPR011701. MFS.
IPR020846. MFS_dom.
IPR016196. MFS_dom_general_subst_transpt.
[Graphical view]
PfamPF07690. MFS_1. 2 hits.
[Graphical view]
SUPFAMSSF103473. SSF103473. 1 hit.
PROSITEPS50850. MFS. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio974391.

Entry information

Entry nameYJ94_YEAST
AccessionPrimary (citable) accession number: P47159
Secondary accession number(s): D6VWU3, Q6Q5M7
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: March 19, 2014
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome X

Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD