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Protein

Uncharacterized membrane protein YJR124C

Gene

YJR124C

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi386 – 393ATPSequence analysis8

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciYEAST:G3O-31745-MONOMER

Protein family/group databases

TCDBi2.A.1.63.4 the major facilitator superfamily (mfs)

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized membrane protein YJR124C
Gene namesi
Ordered Locus Names:YJR124C
ORF Names:J2046
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome X

Organism-specific databases

EuPathDBiFungiDB:YJR124C
SGDiS000003885 YJR124C

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 50ExtracellularSequence analysisAdd BLAST50
Transmembranei51 – 71HelicalSequence analysisAdd BLAST21
Topological domaini72 – 93CytoplasmicSequence analysisAdd BLAST22
Transmembranei94 – 114HelicalSequence analysisAdd BLAST21
Topological domaini115 – 146ExtracellularSequence analysisAdd BLAST32
Transmembranei147 – 167HelicalSequence analysisAdd BLAST21
Topological domaini168 – 184CytoplasmicSequence analysisAdd BLAST17
Transmembranei185 – 205HelicalSequence analysisAdd BLAST21
Topological domaini206 – 260ExtracellularSequence analysisAdd BLAST55
Transmembranei261 – 281HelicalSequence analysisAdd BLAST21
Topological domaini282 – 287CytoplasmicSequence analysis6
Transmembranei288 – 308HelicalSequence analysisAdd BLAST21
Topological domaini309 – 333ExtracellularSequence analysisAdd BLAST25
Transmembranei334 – 354HelicalSequence analysisAdd BLAST21
Topological domaini355 – 386CytoplasmicSequence analysisAdd BLAST32
Transmembranei387 – 407HelicalSequence analysisAdd BLAST21
Topological domaini408 – 416ExtracellularSequence analysis9
Transmembranei417 – 437HelicalSequence analysisAdd BLAST21
Topological domaini438 – 448CytoplasmicSequence analysisAdd BLAST11

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002031181 – 448Uncharacterized membrane protein YJR124CAdd BLAST448

Proteomic databases

MaxQBiP47159
PaxDbiP47159
PRIDEiP47159

PTM databases

iPTMnetiP47159

Interactioni

Protein-protein interaction databases

BioGridi33880, 44 interactors
DIPiDIP-7198N
IntActiP47159, 5 interactors
MINTiP47159
STRINGi4932.YJR124C

Structurei

3D structure databases

ProteinModelPortaliP47159
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000178084
InParanoidiP47159
OMAiDSLGYGF
OrthoDBiEOG092C2F5Z

Family and domain databases

CDDicd06174 MFS, 1 hit
InterProiView protein in InterPro
IPR011701 MFS
IPR020846 MFS_dom
IPR036259 MFS_trans_sf
PfamiView protein in Pfam
PF07690 MFS_1, 2 hits
SUPFAMiSSF103473 SSF103473, 1 hit
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit

Sequencei

Sequence statusi: Complete.

P47159-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPEIFVKFK CASRDIKLLW ASVFLRLLSY GLTNQVLTLF LNAINMTEDK
60 70 80 90 100
IGLFMSLTLA GDVICSYILT WYADSWGRRR VLVYGCAMML LSGLVFSFSE
110 120 130 140 150
NFTLLLVFAI FGVISPSSDE VGPFKSIEEA MIAHLSPHNA RPEIYAIHAL
160 170 180 190 200
VGTIGSALGA IICGIFVDLL KRTGLAATDL QCYKLVFLLY AFFAFCKMVI
210 220 230 240 250
MLLLSDATEL DGHYEHTDCN EETAEPLDVN DETAPLMRQA THPEERSNKL
260 270 280 290 300
SKETVSVLMK LLVIFMVDSL GSGFMTSGWM VYYYSKQFLM GSLALGTLFF
310 320 330 340 350
ITQLVMASST IPSSIIARCF GPVRATLLVQ IPSGIFSILI PMAKNYLPLS
360 370 380 390 400
ILFLNLHFAT TAMDVTPRQI LLTNIIKPRD LTKVMGVVNI GKTFARCVGP
410 420 430 440
IFTGILANNN YLWLCYIISG SLVITADLIL ACMFLGVDAK IKKQMNRH
Length:448
Mass (Da):49,664
Last modified:February 1, 1996 - v1
Checksum:i2319CF9DD1220C14
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti448H → R in AAS56250 (PubMed:17322287).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49624 Genomic DNA Translation: CAA89655.1
AY557924 Genomic DNA Translation: AAS56250.1
BK006943 Genomic DNA Translation: DAA08909.1
PIRiS57147
RefSeqiNP_012658.3, NM_001181782.3

Genome annotation databases

EnsemblFungiiYJR124C; YJR124C; YJR124C
GeneIDi853588
KEGGisce:YJR124C

Similar proteinsi

Entry informationi

Entry nameiYJ94_YEAST
AccessioniPrimary (citable) accession number: P47159
Secondary accession number(s): D6VWU3, Q6Q5M7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: March 28, 2018
This is version 125 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health