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P47159

- YJ94_YEAST

UniProt

P47159 - YJ94_YEAST

Protein

Uncharacterized membrane protein YJR124C

Gene

YJR124C

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 100 (01 Oct 2014)
      Sequence version 1 (01 Feb 1996)
      Previous versions | rss
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    Functioni

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi386 – 3938ATPSequence Analysis

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW

    GO - Biological processi

    1. transmembrane transport Source: InterPro

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciYEAST:G3O-31745-MONOMER.

    Protein family/group databases

    TCDBi2.A.1.63.4. the major facilitator superfamily (mfs).

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Uncharacterized membrane protein YJR124C
    Gene namesi
    Ordered Locus Names:YJR124C
    ORF Names:J2046
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome X

    Organism-specific databases

    CYGDiYJR124c.
    SGDiS000003885. YJR124C.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 448448Uncharacterized membrane protein YJR124CPRO_0000203118Add
    BLAST

    Proteomic databases

    MaxQBiP47159.
    PaxDbiP47159.

    Expressioni

    Gene expression databases

    GenevestigatoriP47159.

    Interactioni

    Protein-protein interaction databases

    BioGridi33880. 12 interactions.
    DIPiDIP-7198N.
    MINTiMINT-2494020.
    STRINGi4932.YJR124C.

    Structurei

    3D structure databases

    ProteinModelPortaliP47159.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 5050ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini72 – 9322CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini115 – 14632ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini168 – 18417CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini206 – 26055ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini282 – 2876CytoplasmicSequence Analysis
    Topological domaini309 – 33325ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini355 – 38632CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini408 – 4169ExtracellularSequence Analysis
    Topological domaini438 – 44811CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei51 – 7121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei94 – 11421HelicalSequence AnalysisAdd
    BLAST
    Transmembranei147 – 16721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei185 – 20521HelicalSequence AnalysisAdd
    BLAST
    Transmembranei261 – 28121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei288 – 30821HelicalSequence AnalysisAdd
    BLAST
    Transmembranei334 – 35421HelicalSequence AnalysisAdd
    BLAST
    Transmembranei387 – 40721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei417 – 43721HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG304962.
    HOGENOMiHOG000178084.
    OMAiMYENERI.
    OrthoDBiEOG7V1G0X.

    Family and domain databases

    InterProiIPR011701. MFS.
    IPR020846. MFS_dom.
    IPR016196. MFS_dom_general_subst_transpt.
    [Graphical view]
    PfamiPF07690. MFS_1. 2 hits.
    [Graphical view]
    SUPFAMiSSF103473. SSF103473. 1 hit.
    PROSITEiPS50850. MFS. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P47159-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAPEIFVKFK CASRDIKLLW ASVFLRLLSY GLTNQVLTLF LNAINMTEDK    50
    IGLFMSLTLA GDVICSYILT WYADSWGRRR VLVYGCAMML LSGLVFSFSE 100
    NFTLLLVFAI FGVISPSSDE VGPFKSIEEA MIAHLSPHNA RPEIYAIHAL 150
    VGTIGSALGA IICGIFVDLL KRTGLAATDL QCYKLVFLLY AFFAFCKMVI 200
    MLLLSDATEL DGHYEHTDCN EETAEPLDVN DETAPLMRQA THPEERSNKL 250
    SKETVSVLMK LLVIFMVDSL GSGFMTSGWM VYYYSKQFLM GSLALGTLFF 300
    ITQLVMASST IPSSIIARCF GPVRATLLVQ IPSGIFSILI PMAKNYLPLS 350
    ILFLNLHFAT TAMDVTPRQI LLTNIIKPRD LTKVMGVVNI GKTFARCVGP 400
    IFTGILANNN YLWLCYIISG SLVITADLIL ACMFLGVDAK IKKQMNRH 448
    Length:448
    Mass (Da):49,664
    Last modified:February 1, 1996 - v1
    Checksum:i2319CF9DD1220C14
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti448 – 4481H → R in AAS56250. (PubMed:17322287)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z49624 Genomic DNA. Translation: CAA89655.1.
    AY557924 Genomic DNA. Translation: AAS56250.1.
    BK006943 Genomic DNA. Translation: DAA08909.1.
    PIRiS57147.
    RefSeqiNP_012658.3. NM_001181782.3.

    Genome annotation databases

    EnsemblFungiiYJR124C; YJR124C; YJR124C.
    GeneIDi853588.
    KEGGisce:YJR124C.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z49624 Genomic DNA. Translation: CAA89655.1 .
    AY557924 Genomic DNA. Translation: AAS56250.1 .
    BK006943 Genomic DNA. Translation: DAA08909.1 .
    PIRi S57147.
    RefSeqi NP_012658.3. NM_001181782.3.

    3D structure databases

    ProteinModelPortali P47159.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 33880. 12 interactions.
    DIPi DIP-7198N.
    MINTi MINT-2494020.
    STRINGi 4932.YJR124C.

    Protein family/group databases

    TCDBi 2.A.1.63.4. the major facilitator superfamily (mfs).

    Proteomic databases

    MaxQBi P47159.
    PaxDbi P47159.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YJR124C ; YJR124C ; YJR124C .
    GeneIDi 853588.
    KEGGi sce:YJR124C.

    Organism-specific databases

    CYGDi YJR124c.
    SGDi S000003885. YJR124C.

    Phylogenomic databases

    eggNOGi NOG304962.
    HOGENOMi HOG000178084.
    OMAi MYENERI.
    OrthoDBi EOG7V1G0X.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-31745-MONOMER.

    Miscellaneous databases

    NextBioi 974391.

    Gene expression databases

    Genevestigatori P47159.

    Family and domain databases

    InterProi IPR011701. MFS.
    IPR020846. MFS_dom.
    IPR016196. MFS_dom_general_subst_transpt.
    [Graphical view ]
    Pfami PF07690. MFS_1. 2 hits.
    [Graphical view ]
    SUPFAMi SSF103473. SSF103473. 1 hit.
    PROSITEi PS50850. MFS. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."
      Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K.
      , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.
      EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    4. "A global topology map of the Saccharomyces cerevisiae membrane proteome."
      Kim H., Melen K., Oesterberg M., von Heijne G.
      Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
      Strain: ATCC 208353 / W303-1A.

    Entry informationi

    Entry nameiYJ94_YEAST
    AccessioniPrimary (citable) accession number: P47159
    Secondary accession number(s): D6VWU3, Q6Q5M7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1996
    Last sequence update: February 1, 1996
    Last modified: October 1, 2014
    This is version 100 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    2. Yeast chromosome X
      Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

    External Data

    Dasty 3