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P47159

- YJ94_YEAST

UniProt

P47159 - YJ94_YEAST

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Protein

Uncharacterized membrane protein YJR124C

Gene

YJR124C

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi386 – 3938ATPSequence Analysis

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW

GO - Biological processi

  1. transmembrane transport Source: InterPro
Complete GO annotation...

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciYEAST:G3O-31745-MONOMER.

Protein family/group databases

TCDBi2.A.1.63.4. the major facilitator superfamily (mfs).

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized membrane protein YJR124C
Gene namesi
Ordered Locus Names:YJR124C
ORF Names:J2046
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome X

Organism-specific databases

CYGDiYJR124c.
SGDiS000003885. YJR124C.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 448448Uncharacterized membrane protein YJR124CPRO_0000203118Add
BLAST

Proteomic databases

MaxQBiP47159.
PaxDbiP47159.

Expressioni

Gene expression databases

GenevestigatoriP47159.

Interactioni

Protein-protein interaction databases

BioGridi33880. 12 interactions.
DIPiDIP-7198N.
MINTiMINT-2494020.
STRINGi4932.YJR124C.

Structurei

3D structure databases

ProteinModelPortaliP47159.
ModBaseiSearch...
MobiDBiSearch...

Topological domain

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 5050ExtracellularSequence AnalysisAdd
BLAST
Topological domaini72 – 9322CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini115 – 14632ExtracellularSequence AnalysisAdd
BLAST
Topological domaini168 – 18417CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini206 – 26055ExtracellularSequence AnalysisAdd
BLAST
Topological domaini282 – 2876CytoplasmicSequence Analysis
Topological domaini309 – 33325ExtracellularSequence AnalysisAdd
BLAST
Topological domaini355 – 38632CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini408 – 4169ExtracellularSequence Analysis
Topological domaini438 – 44811CytoplasmicSequence AnalysisAdd
BLAST

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei51 – 7121HelicalSequence AnalysisAdd
BLAST
Transmembranei94 – 11421HelicalSequence AnalysisAdd
BLAST
Transmembranei147 – 16721HelicalSequence AnalysisAdd
BLAST
Transmembranei185 – 20521HelicalSequence AnalysisAdd
BLAST
Transmembranei261 – 28121HelicalSequence AnalysisAdd
BLAST
Transmembranei288 – 30821HelicalSequence AnalysisAdd
BLAST
Transmembranei334 – 35421HelicalSequence AnalysisAdd
BLAST
Transmembranei387 – 40721HelicalSequence AnalysisAdd
BLAST
Transmembranei417 – 43721HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG304962.
HOGENOMiHOG000178084.
InParanoidiP47159.
OMAiMYENERI.
OrthoDBiEOG7V1G0X.

Family and domain databases

InterProiIPR011701. MFS.
IPR020846. MFS_dom.
IPR016196. MFS_dom_general_subst_transpt.
[Graphical view]
PfamiPF07690. MFS_1. 2 hits.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P47159-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAPEIFVKFK CASRDIKLLW ASVFLRLLSY GLTNQVLTLF LNAINMTEDK
60 70 80 90 100
IGLFMSLTLA GDVICSYILT WYADSWGRRR VLVYGCAMML LSGLVFSFSE
110 120 130 140 150
NFTLLLVFAI FGVISPSSDE VGPFKSIEEA MIAHLSPHNA RPEIYAIHAL
160 170 180 190 200
VGTIGSALGA IICGIFVDLL KRTGLAATDL QCYKLVFLLY AFFAFCKMVI
210 220 230 240 250
MLLLSDATEL DGHYEHTDCN EETAEPLDVN DETAPLMRQA THPEERSNKL
260 270 280 290 300
SKETVSVLMK LLVIFMVDSL GSGFMTSGWM VYYYSKQFLM GSLALGTLFF
310 320 330 340 350
ITQLVMASST IPSSIIARCF GPVRATLLVQ IPSGIFSILI PMAKNYLPLS
360 370 380 390 400
ILFLNLHFAT TAMDVTPRQI LLTNIIKPRD LTKVMGVVNI GKTFARCVGP
410 420 430 440
IFTGILANNN YLWLCYIISG SLVITADLIL ACMFLGVDAK IKKQMNRH
Length:448
Mass (Da):49,664
Last modified:February 1, 1996 - v1
Checksum:i2319CF9DD1220C14
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti448 – 4481H → R in AAS56250. (PubMed:17322287)Curated

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z49624 Genomic DNA. Translation: CAA89655.1.
AY557924 Genomic DNA. Translation: AAS56250.1.
BK006943 Genomic DNA. Translation: DAA08909.1.
PIRiS57147.
RefSeqiNP_012658.3. NM_001181782.3.

Genome annotation databases

EnsemblFungiiYJR124C; YJR124C; YJR124C.
GeneIDi853588.
KEGGisce:YJR124C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z49624 Genomic DNA. Translation: CAA89655.1 .
AY557924 Genomic DNA. Translation: AAS56250.1 .
BK006943 Genomic DNA. Translation: DAA08909.1 .
PIRi S57147.
RefSeqi NP_012658.3. NM_001181782.3.

3D structure databases

ProteinModelPortali P47159.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 33880. 12 interactions.
DIPi DIP-7198N.
MINTi MINT-2494020.
STRINGi 4932.YJR124C.

Protein family/group databases

TCDBi 2.A.1.63.4. the major facilitator superfamily (mfs).

Proteomic databases

MaxQBi P47159.
PaxDbi P47159.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YJR124C ; YJR124C ; YJR124C .
GeneIDi 853588.
KEGGi sce:YJR124C.

Organism-specific databases

CYGDi YJR124c.
SGDi S000003885. YJR124C.

Phylogenomic databases

eggNOGi NOG304962.
HOGENOMi HOG000178084.
InParanoidi P47159.
OMAi MYENERI.
OrthoDBi EOG7V1G0X.

Enzyme and pathway databases

BioCyci YEAST:G3O-31745-MONOMER.

Miscellaneous databases

NextBioi 974391.

Gene expression databases

Genevestigatori P47159.

Family and domain databases

InterProi IPR011701. MFS.
IPR020846. MFS_dom.
IPR016196. MFS_dom_general_subst_transpt.
[Graphical view ]
Pfami PF07690. MFS_1. 2 hits.
[Graphical view ]
SUPFAMi SSF103473. SSF103473. 1 hit.
PROSITEi PS50850. MFS. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."
    Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K.
    , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.
    EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. "A global topology map of the Saccharomyces cerevisiae membrane proteome."
    Kim H., Melen K., Oesterberg M., von Heijne G.
    Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: ATCC 208353 / W303-1A.

Entry informationi

Entry nameiYJ94_YEAST
AccessioniPrimary (citable) accession number: P47159
Secondary accession number(s): D6VWU3, Q6Q5M7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: October 29, 2014
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome X
    Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

External Data

Dasty 3