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Protein

Putative transferase CAF17, mitochondrial

Gene

IBA57

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Required for lysine and glutamate prototrophy and mitochondrial genome maintenance. Has a role in the maturation of mitochondrial aconitase-type and radical-SAM Fe/S proteins biotin synthase and lipoic acid synthase.1 Publication

Miscellaneous

Present with 2960 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

GO - Biological processi

  • protein maturation by iron-sulfur cluster transfer Source: SGD

Keywordsi

Molecular functionTransferase

Enzyme and pathway databases

BioCyciYEAST:G3O-31743-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Putative transferase CAF17, mitochondrial (EC:2.1.-.-)
Alternative name(s):
57 kDa iron-sulfur cluster assembly factor for biotin synthase- and aconitase-like mitochondrial proteins
CCR4-associated factor 17
Gene namesi
Name:IBA57
Synonyms:CAF17
Ordered Locus Names:YJR122W
ORF Names:J2043
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome X

Organism-specific databases

EuPathDBiFungiDB:YJR122W
SGDiS000003883 IBA57

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 27MitochondrionSequence analysisAdd BLAST27
ChainiPRO_000020311728 – 497Putative transferase CAF17, mitochondrialAdd BLAST470

Proteomic databases

MaxQBiP47158
PaxDbiP47158
PRIDEiP47158

Expressioni

Inductioni

Up-regulated during calcium shortage.1 Publication

Interactioni

Subunit structurei

Interacts with CCR4, ISA1 and ISA2.2 Publications

Protein-protein interaction databases

BioGridi33878, 16 interactors
DIPiDIP-1404N
IntActiP47158, 13 interactors
MINTiP47158
STRINGi4932.YJR122W

Structurei

3D structure databases

ProteinModelPortaliP47158
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GcvT family. CAF17 subfamily.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

GeneTreeiENSGT00390000006465
HOGENOMiHOG000000825
InParanoidiP47158
KOiK22073
OrthoDBiEOG092C2229

Family and domain databases

InterProiView protein in InterPro
IPR017703 YgfZ/GcvT_CS
TIGRFAMsiTIGR03317 ygfZ_signature, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P47158-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFISRRCRIK GFTLKNLLWF RSSSTRFVST ESPDASAITK PDGIFNYSLL
60 70 80 90 100
ENRTYIRIRG PDTVKFLNGL VTSKLLPHFI KKNLTTVEEN EVPTEEGTTK
110 120 130 140 150
VDPIIPVPEF DARLGNWGLY NEKGIQGPYI SRFGLYSAFL NGKGKLITDT
160 170 180 190 200
IIYPTPVTVS EQISNYPEYL LELHGNVVDK ILHVLQTHKL ANKIKFEKID
210 220 230 240 250
HSSLKTWDVE VQFPNLPKDI ENPWFDNLLD PMALPKNSID ANNFAVNVLN
260 270 280 290 300
SLFNSDPRIL GIYVERRTES MSRHYSTFPQ SFRVVTSEQV DDLSKLFNFN
310 320 330 340 350
VFDFPFQVNK KASVQVREIR FQKGLIDSTE DYISETLLPL ELNFDFFPNT
360 370 380 390 400
ISTNKGCYVG QELTARTYAT GILRKRLVPV KLDNYQLLDT DPERKYAEFH
410 420 430 440 450
IDNVVEKSLA ENEPTLNPFT NKPPERTKRK QRPAGLLISN EGLYGVALLR
460 470 480 490
TEHFSAAFSS DEPVEFYITT TKGENIKITP QKPFWFSDWK NNNGPHK
Length:497
Mass (Da):57,055
Last modified:February 1, 1996 - v1
Checksum:iA9970EBD3BF6019C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49622 Genomic DNA Translation: CAA89653.1
BK006943 Genomic DNA Translation: DAA08907.1
PIRiS57145
RefSeqiNP_012656.1, NM_001181780.1

Genome annotation databases

EnsemblFungiiYJR122W; YJR122W; YJR122W
GeneIDi853586
KEGGisce:YJR122W

Similar proteinsi

Entry informationi

Entry nameiCAF17_YEAST
AccessioniPrimary (citable) accession number: P47158
Secondary accession number(s): D6VWU1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: May 23, 2018
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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