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Protein

Altered inheritance rate of mitochondria protein 25

Gene

AIM25

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

  • cellular response to heat Source: SGD
  • cellular response to oxidative stress Source: SGD
  • chronological cell aging Source: SGD
  • negative regulation of mitophagy Source: SGD

Enzyme and pathway databases

BioCyciYEAST:G3O-31728-MONOMER.

Protein family/group databases

TCDBi9.A.36.1.2. the ca(2+)-dependent phospholipid scramblase (scramblase) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Altered inheritance rate of mitochondria protein 25
Gene namesi
Name:AIM25
Ordered Locus Names:YJR100C
ORF Names:J1946
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome X

Organism-specific databases

EuPathDBiFungiDB:YJR100C.
SGDiS000003861. AIM25.

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002031091 – 327Altered inheritance rate of mitochondria protein 25Add BLAST327

Proteomic databases

PRIDEiP47140.

Interactioni

Protein-protein interaction databases

BioGridi33855. 64 interactors.
DIPiDIP-4704N.
IntActiP47140. 2 interactors.
MINTiMINT-512473.

Structurei

3D structure databases

ProteinModelPortaliP47140.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the phospholipid scramblase family.Curated

Phylogenomic databases

HOGENOMiHOG000248395.
InParanoidiP47140.
OMAiFRTHRPF.
OrthoDBiEOG092C3USR.

Family and domain databases

InterProiView protein in InterPro
IPR005552. Scramblase.
PANTHERiPTHR23248. PTHR23248. 1 hit.
PfamiView protein in Pfam
PF03803. Scramblase. 1 hit.

Sequencei

Sequence statusi: Complete.

P47140-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHRTAIFLTY RSCMRNFSTL SKTLTVSSGK VIRNGPFRRV IREKNQITKA
60 70 80 90 100
PSVKAFKENS NSGIIKVHDP IATTILNEPT VIIERQIEFM NVFLGFEQAN
110 120 130 140 150
RYAIMDVNGN KIASMMERDF SITKAIMRQF YRLHRPFLVD VFDNWGNVIM
160 170 180 190 200
TIKRPFSFIN SHIKTIIPPS AYVDNGSDST HYHDGKEGTT VGETIQNWHL
210 220 230 240 250
WRRRYELFQK DGVEGSTFDQ FGKIDAPFLS FDFPVTDADG KIMASVDRNW
260 270 280 290 300
VGLGREMFTD TGVYVVRFDS QRCFDNIYPT EMLSSQVLTL DQRAVLLANA
310 320
VSIDFDYFSR HSRQTGGFLS FGGGYDE
Length:327
Mass (Da):37,480
Last modified:February 1, 1996 - v1
Checksum:i9861130EB60D75A7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49600 Genomic DNA. Translation: CAA89630.1.
BK006943 Genomic DNA. Translation: DAA08885.1.
PIRiS57121.
RefSeqiNP_012634.3. NM_001181758.3.

Genome annotation databases

EnsemblFungiiYJR100C; YJR100C; YJR100C.
GeneIDi853563.
KEGGisce:YJR100C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49600 Genomic DNA. Translation: CAA89630.1.
BK006943 Genomic DNA. Translation: DAA08885.1.
PIRiS57121.
RefSeqiNP_012634.3. NM_001181758.3.

3D structure databases

ProteinModelPortaliP47140.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi33855. 64 interactors.
DIPiDIP-4704N.
IntActiP47140. 2 interactors.
MINTiMINT-512473.

Protein family/group databases

TCDBi9.A.36.1.2. the ca(2+)-dependent phospholipid scramblase (scramblase) family.

Proteomic databases

PRIDEiP47140.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYJR100C; YJR100C; YJR100C.
GeneIDi853563.
KEGGisce:YJR100C.

Organism-specific databases

EuPathDBiFungiDB:YJR100C.
SGDiS000003861. AIM25.

Phylogenomic databases

HOGENOMiHOG000248395.
InParanoidiP47140.
OMAiFRTHRPF.
OrthoDBiEOG092C3USR.

Enzyme and pathway databases

BioCyciYEAST:G3O-31728-MONOMER.

Miscellaneous databases

PROiPR:P47140.

Family and domain databases

InterProiView protein in InterPro
IPR005552. Scramblase.
PANTHERiPTHR23248. PTHR23248. 1 hit.
PfamiView protein in Pfam
PF03803. Scramblase. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiAIM25_YEAST
AccessioniPrimary (citable) accession number: P47140
Secondary accession number(s): D6VWR9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: June 7, 2017
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome X
    Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.