P47140 (AIM25_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Altered inheritance rate of mitochondria protein 25

Gene names

Name:	AIM25
Ordered Locus Names:	YJR100C
ORF Names:	J1946

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae

Protein attributes

Sequence length	327 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location	Mitochondrion Ref.3.
Sequence similarities	Belongs to the phospholipid scramblase family.

Ontologies

Keywords
Cellular component	Mitochondrion
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	mitochondrion Inferred from direct assay Ref.3. Source: SGD
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 327	327	Altered inheritance rate of mitochondria protein 25		PRO_0000203109

Sequences

	Sequence		Length	Mass (Da)
	P47140 [UniParc]. Last modified February 1, 1996. Version 1. Checksum: 9861130EB60D75A7	FASTA	327	37,480
	10 20 30 40 50 60 MHRTAIFLTY RSCMRNFSTL SKTLTVSSGK VIRNGPFRRV IREKNQITKA PSVKAFKENS 70 80 90 100 110 120 NSGIIKVHDP IATTILNEPT VIIERQIEFM NVFLGFEQAN RYAIMDVNGN KIASMMERDF 130 140 150 160 170 180 SITKAIMRQF YRLHRPFLVD VFDNWGNVIM TIKRPFSFIN SHIKTIIPPS AYVDNGSDST 190 200 210 220 230 240 HYHDGKEGTT VGETIQNWHL WRRRYELFQK DGVEGSTFDQ FGKIDAPFLS FDFPVTDADG 250 260 270 280 290 300 KIMASVDRNW VGLGREMFTD TGVYVVRFDS QRCFDNIYPT EMLSSQVLTL DQRAVLLANA 310 320 VSIDFDYFSR HSRQTGGFLS FGGGYDE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X." Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K. , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L. EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	"Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics." Reinders J., Zahedi R.P., Pfanner N., Meisinger C., Sickmann A. J. Proteome Res. 5:1543-1554(2006) [PubMed] [Europe PMC] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS], MASS SPECTROMETRY.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z49600 Genomic DNA. Translation: CAA89630.1. BK006943 Genomic DNA. Translation: DAA08885.1.
PIR	S57121.
RefSeq	NP_012634.3. NM_001181758.3.
3D structure databases
ProteinModelPortal	P47140.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-4704N.
IntAct	P47140. 2 interactions.
MINT	MINT-512473.
STRING	4932.YJR100C.
Protein family/group databases
TCDB	9.A.36.1.2. Ca2+-dependent phospholipid scramblase family.
Proteomic databases
PaxDb	P47140.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YJR100C; YJR100C; YJR100C.
GeneID	853563.
KEGG	sce:YJR100C. sce:YJR103W.
Organism-specific databases
CYGD	YJR100c.
SGD	S000003861. AIM25.
Phylogenomic databases
eggNOG	NOG238252.
HOGENOM	HOG000248395.
KO	K01937.
OMA	IKRPFSF.
OrthoDB	EOG4KWP33.
Gene expression databases
Genevestigator	P47140.
GermOnline	YJR100C. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR005552. Scramblase. [Graphical view]
PANTHER	PTHR23248. PTHR23248. 1 hit.
Pfam	PF03803. Scramblase. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	974320.

Entry information

Entry name

AIM25_YEAST

Accession

Primary (citable) accession number: P47140
Secondary accession number(s): D6VWR9

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1996
Last sequence update:	February 1, 1996
Last modified:	April 3, 2013
This is version 79 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program