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P47137 (YJ66_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 120. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Uncharacterized oxidoreductase YJR096W

EC=1.-.-.-
Gene names
Ordered Locus Names:YJR096W
ORF Names:J1926
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length282 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Miscellaneous

Present with 6960 molecules/cell in log phase SD medium.

Sequence similarities

Belongs to the aldo/keto reductase family.

Binary interactions

With

Entry

#Exp.

IntAct

Notes

PRP40P332032EBI-25572,EBI-701
RSP5P399403EBI-25572,EBI-16219

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 282282Uncharacterized oxidoreductase YJR096W
PRO_0000124679

Sites

Active site501Proton donor By similarity
Binding site1151Substrate By similarity
Site811Lowers pKa of active site Tyr By similarity

Sequences

Sequence LengthMass (Da)Tools
P47137 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: 692F14FB0B504B95

FASTA28232,344
        10         20         30         40         50         60 
MVPKFYKLSN GFKIPSIALG TYDIPRSQTA EIVYEGVKCG YRHFDTAVLY GNEKEVGDGI 

        70         80         90        100        110        120 
IKWLNEDPGN HKREEIFYTT KLWNSQNGYK RAKAAIRQCL NEVSGLQYID LLLIHSPLEG 

       130        140        150        160        170        180 
SKLRLETWRA MQEAVDEGLV KSIGVSNYGK KHIDELLNWP ELKHKPVVNQ IEISPWIMRQ 

       190        200        210        220        230        240 
ELADYCKSKG LVVEAFAPLC HGYKMTNPDL LKVCKEVDRN PGQVLIRWSL QHGYLPLPKT 

       250        260        270        280 
KTVKRLEGNL AAYNFELSDE QMKFLDHPDA YEPTDWECTD AP 

« Hide

References

« Hide 'large scale' references
[1]"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."
Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K. expand/collapse author list , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.
EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[4]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z49596 Genomic DNA. Translation: CAA89626.1.
AY558257 Genomic DNA. Translation: AAS56583.1.
BK006943 Genomic DNA. Translation: DAA08881.1.
PIRS57117.
RefSeqNP_012630.1. NM_001181754.1.

3D structure databases

ProteinModelPortalP47137.
SMRP47137. Positions 2-282.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid33851. 39 interactions.
IntActP47137. 9 interactions.
MINTMINT-2492473.
STRING4932.YJR096W.

Proteomic databases

MaxQBP47137.
PaxDbP47137.
PeptideAtlasP47137.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYJR096W; YJR096W; YJR096W.
GeneID853559.
KEGGsce:YJR096W.

Organism-specific databases

CYGDYJR096w.
SGDS000003857. YJR096W.

Phylogenomic databases

eggNOGCOG0656.
GeneTreeENSGT00750000118266.
HOGENOMHOG000250272.
OMAHANCERT.
OrthoDBEOG7WQ83S.

Enzyme and pathway databases

BioCycYEAST:G3O-31724-MONOMER.

Gene expression databases

GenevestigatorP47137.

Family and domain databases

Gene3D3.20.20.100. 1 hit.
InterProIPR001395. Aldo/ket_red.
IPR018170. Aldo/ket_reductase_CS.
IPR020471. Aldo/keto_reductase_subgr.
IPR023210. NADP_OxRdtase_dom.
[Graphical view]
PANTHERPTHR11732. PTHR11732. 1 hit.
PfamPF00248. Aldo_ket_red. 1 hit.
[Graphical view]
PIRSFPIRSF000097. AKR. 1 hit.
PRINTSPR00069. ALDKETRDTASE.
SUPFAMSSF51430. SSF51430. 1 hit.
PROSITEPS00798. ALDOKETO_REDUCTASE_1. 1 hit.
PS00062. ALDOKETO_REDUCTASE_2. 1 hit.
PS00063. ALDOKETO_REDUCTASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio974308.

Entry information

Entry nameYJ66_YEAST
AccessionPrimary (citable) accession number: P47137
Secondary accession number(s): D6VWR5
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: June 11, 2014
This is version 120 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome X

Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families