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Protein

Protein JSN1

Gene

JSN1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • mRNA binding Source: SGD
  • nucleotide binding Source: InterPro

GO - Biological processi

  • cellular protein complex localization Source: SGD
  • establishment of mitochondrion localization Source: SGD
  • nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay Source: SGD
Complete GO annotation...

Keywords - Ligandi

RNA-binding

Enzyme and pathway databases

BioCyciYEAST:G3O-31718-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein JSN1
Alternative name(s):
Pumilio homology domain family member 1
Gene namesi
Name:JSN1
Synonyms:PUF1
Ordered Locus Names:YJR091C
ORF Names:J1890
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome X

Organism-specific databases

EuPathDBiFungiDB:YJR091C.
SGDiS000003851. JSN1.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: SGD
  • cytoplasmic side of mitochondrial outer membrane Source: SGD
  • fungal-type cell wall Source: SGD
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000759221 – 1091Protein JSN1Add BLAST1091

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei129PhosphoserineCombined sources1
Modified residuei131PhosphothreonineCombined sources1
Modified residuei160PhosphoserineCombined sources1
Modified residuei168PhosphoserineCombined sources1
Modified residuei913PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP47135.
PRIDEiP47135.

PTM databases

iPTMnetiP47135.

Interactioni

Protein-protein interaction databases

BioGridi33845. 64 interactors.
DIPiDIP-1281N.
IntActiP47135. 39 interactors.
MINTiMINT-405099.

Structurei

3D structure databases

ProteinModelPortaliP47135.
SMRiP47135.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini340 – 426RRMPROSITE-ProRule annotationAdd BLAST87
Domaini557 – 913PUM-HDPROSITE-ProRule annotationAdd BLAST357
Repeati617 – 652Pumilio 1Add BLAST36
Repeati653 – 689Pumilio 2Add BLAST37
Repeati690 – 724Pumilio 3Add BLAST35
Repeati725 – 760Pumilio 4Add BLAST36
Repeati801 – 837Pumilio 5Add BLAST37

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi507 – 510Poly-Asn4
Compositional biasi515 – 518Poly-Asn4
Compositional biasi923 – 927Poly-Gln5
Compositional biasi967 – 970Poly-Thr4
Compositional biasi1065 – 1076Poly-AsnAdd BLAST12

Sequence similaritiesi

Contains 1 PUM-HD domain.PROSITE-ProRule annotation
Contains 5 pumilio repeats.PROSITE-ProRule annotation
Contains 1 RRM (RNA recognition motif) domain.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

GeneTreeiENSGT00730000112282.
HOGENOMiHOG000113136.
InParanoidiP47135.
KOiK17974.
OMAiNGTWACQ.
OrthoDBiEOG092C1612.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
3.30.70.330. 1 hit.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR012677. Nucleotide-bd_a/b_plait.
IPR033133. PUM-HD.
IPR001313. Pumilio_RNA-bd_rpt.
IPR000504. RRM_dom.
[Graphical view]
PfamiPF00806. PUF. 3 hits.
PF00076. RRM_1. 1 hit.
[Graphical view]
SMARTiSM00025. Pumilio. 6 hits.
SM00360. RRM. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.
SSF54928. SSF54928. 1 hit.
PROSITEiPS50302. PUM. 5 hits.
PS50303. PUM_HD. 1 hit.
PS50102. RRM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P47135-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDKSKQMNIN NLSNIPEVID PGITIPIYEE EYENNGESNS QLQQQPQKLG
60 70 80 90 100
SYRSRAGKFS NTLSNLLPSI SAKLHHSKKN SHGKNGAEFS SSNNSSQSTV
110 120 130 140 150
ASKTPRASPS RSKMMESSID GVTMDRPGSL TPPQDMEKLV HFPDSSNNFL
160 170 180 190 200
IPAPRGSSDS FNLPHQISRT RNNTMSSQIT SISSIAPKPR TSSGIWSSNA
210 220 230 240 250
SANDPMQQHL LQQLQPTTSN NTTNSNTLND YSTKTAYFDN MVSTSGSQMA
260 270 280 290 300
DNKMNTNNLA IPNSVWSNTR QRSQSNASSI YTDAPLYEQP ARASISSHYT
310 320 330 340 350
IPTQESPLIA DEIDPQSINW VTMDPTVPSI NQISNLLPTN TISISNVFPL
360 370 380 390 400
QHQQPQLNNA INLTSTSLAT LCSKYGEVIS ARTLRNLNMA LVEFSSVESA
410 420 430 440 450
VKALDSLQGK EVSMIGAPSK ISFAKILPMH QQPPQFLLNS QGLPLGLENN
460 470 480 490 500
NLQPQPLLQE QLFNGAVTFQ QQGNVSIPVF NQQSQQSQHQ NHSSGSAGFS
510 520 530 540 550
NVLHGYNNNN SMHGNNNNSA NEKEQCPFPL PPPNVNEKED LLREIIELFE
560 570 580 590 600
ANSDEYQINS LIKKSLNHKG TSDTQNFGPL PEPLSGREFD PPKLRELRKS
610 620 630 640 650
IDSNAFSDLE IEQLAIAMLD ELPELSSDYL GNTIVQKLFE HSSDIIKDIM
660 670 680 690 700
LRKTSKYLTS MGVHKNGTWA CQKMITMAHT PRQIMQVTQG VKDYCTPLIN
710 720 730 740 750
DQFGNYVIQC VLKFGFPWNQ FIFESIIANF WVIVQNRYGA RAVRACLEAH
760 770 780 790 800
DIVTPEQSIV LSAMIVTYAE YLSTNSNGAL LVTWFLDTSV LPNRHSILAP
810 820 830 840 850
RLTKRIVELC GHRLASLTIL KVLNYRGDDN ARKIILDSLF GNVNAHDSSP
860 870 880 890 900
PKELTKLLCE TNYGPTFVHK VLAMPLLEDD LRAHIIKQVR KVLTDSTQIQ
910 920 930 940 950
PSRRLLEEVG LASPSSTHNK TKQQQQQHHN SSISHMFATP DTSGQHMRGL
960 970 980 990 1000
SVSSVKSGGS KHTTMNTTTT NGSSASTLSP GQPLNANSNS SMGYFSYPGV
1010 1020 1030 1040 1050
FPVSGFSGNA SNGYAMNNDD LSSQFDMLNF NNGTRLSLPQ LSLTNHNNTT
1060 1070 1080 1090
MELVNNVGSS QPHTNNNNNN NNTNYNDDNT VFETLTLHSA N
Length:1,091
Mass (Da):120,374
Last modified:February 1, 1996 - v1
Checksum:iA168489189C67B22
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L43493 Genomic DNA. Translation: AAC41666.1.
Z49591 Genomic DNA. Translation: CAA89618.1.
L47993 Genomic DNA. Translation: AAB39314.1.
BK006943 Genomic DNA. Translation: DAA08875.1.
PIRiS57112.
RefSeqiNP_012624.1. NM_001181748.1.

Genome annotation databases

EnsemblFungiiYJR091C; YJR091C; YJR091C.
GeneIDi853553.
KEGGisce:YJR091C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L43493 Genomic DNA. Translation: AAC41666.1.
Z49591 Genomic DNA. Translation: CAA89618.1.
L47993 Genomic DNA. Translation: AAB39314.1.
BK006943 Genomic DNA. Translation: DAA08875.1.
PIRiS57112.
RefSeqiNP_012624.1. NM_001181748.1.

3D structure databases

ProteinModelPortaliP47135.
SMRiP47135.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi33845. 64 interactors.
DIPiDIP-1281N.
IntActiP47135. 39 interactors.
MINTiMINT-405099.

PTM databases

iPTMnetiP47135.

Proteomic databases

MaxQBiP47135.
PRIDEiP47135.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYJR091C; YJR091C; YJR091C.
GeneIDi853553.
KEGGisce:YJR091C.

Organism-specific databases

EuPathDBiFungiDB:YJR091C.
SGDiS000003851. JSN1.

Phylogenomic databases

GeneTreeiENSGT00730000112282.
HOGENOMiHOG000113136.
InParanoidiP47135.
KOiK17974.
OMAiNGTWACQ.
OrthoDBiEOG092C1612.

Enzyme and pathway databases

BioCyciYEAST:G3O-31718-MONOMER.

Miscellaneous databases

PROiP47135.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
3.30.70.330. 1 hit.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR012677. Nucleotide-bd_a/b_plait.
IPR033133. PUM-HD.
IPR001313. Pumilio_RNA-bd_rpt.
IPR000504. RRM_dom.
[Graphical view]
PfamiPF00806. PUF. 3 hits.
PF00076. RRM_1. 1 hit.
[Graphical view]
SMARTiSM00025. Pumilio. 6 hits.
SM00360. RRM. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.
SSF54928. SSF54928. 1 hit.
PROSITEiPS50302. PUM. 5 hits.
PS50303. PUM_HD. 1 hit.
PS50102. RRM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiJSN1_YEAST
AccessioniPrimary (citable) accession number: P47135
Secondary accession number(s): D6VWQ9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: November 2, 2016
This is version 147 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 784 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome X
    Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.