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P47131 (YJ55_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 97. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
UPF0136 membrane protein YJR085C
Gene names
Ordered Locus Names:YJR085C
ORF Names:J1863
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length105 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Mitochondrion. Membrane; Multi-pass membrane protein Potential Ref.6 Ref.7.

Induction

By the DNA-damaging agent methyl methanesulphonate (MMS) (at protein level). Ref.8

Miscellaneous

Present with 2100 molecules/cell in log phase SD medium.

Sequence similarities

Belongs to the UPF0136 (TMEM14) family.

Ontologies

Keywords
   Cellular componentMembrane
Mitochondrion
   DomainTransmembrane
Transmembrane helix
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

mitochondrion

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Binary interactions

With

Entry

#Exp.

IntAct

Notes

TSA2Q041201EBI-25560,EBI-19631

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 105105UPF0136 membrane protein YJR085C
PRO_0000203105

Regions

Transmembrane26 – 4621Helical; Potential
Transmembrane53 – 7321Helical; Potential
Transmembrane77 – 9721Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
P47131 [UniParc].

Last modified February 1, 1996. Version 1.
Checksum: C35A1E8AB98CFFA0

FASTA10511,250
        10         20         30         40         50         60 
MEHPAYTLSL LTTAGGLMGY YRKGSIPSLV SGLVFGSVYG IAGYLLHMNR DGGLEMALGA 

        70         80         90        100 
STLLLGAGVI RGMPSRFTKP VPVVLTALGG LGSYYYYNKY KEFYP 

« Hide

References

« Hide 'large scale' references
[1]"Analysis of a 62 kb DNA sequence of chromosome X reveals 36 open reading frames and a gene cluster with a counterpart on chromosome XI."
Huang M.-E., Manus V., Chuat J.-C., Galibert F.
Yeast 12:869-875(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."
Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K. expand/collapse author list , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.
EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[5]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[6]"The proteome of Saccharomyces cerevisiae mitochondria."
Sickmann A., Reinders J., Wagner Y., Joppich C., Zahedi R.P., Meyer H.E., Schoenfisch B., Perschil I., Chacinska A., Guiard B., Rehling P., Pfanner N., Meisinger C.
Proc. Natl. Acad. Sci. U.S.A. 100:13207-13212(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
Strain: ATCC 76625 / YPH499.
[7]"Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics."
Reinders J., Zahedi R.P., Pfanner N., Meisinger C., Sickmann A.
J. Proteome Res. 5:1543-1554(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[8]"Global protein expression profiling of budding yeast in response to DNA damage."
Lee M.-W., Kim B.-J., Choi H.-K., Ryu M.-J., Kim S.-B., Kang K.-M., Cho E.-J., Youn H.-D., Huh W.-K., Kim S.-T.
Yeast 24:145-154(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: INDUCTION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z49585 Genomic DNA. Translation: CAA89612.1.
L47993 Genomic DNA. Translation: AAB39308.1.
AY557887 Genomic DNA. Translation: AAS56213.1.
BK006943 Genomic DNA. Translation: DAA08870.1.
PIRS57104.
RefSeqNP_012618.3. NM_001181742.3.

3D structure databases

ProteinModelPortalP47131.
SMRP47131. Positions 1-104.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid33840. 6 interactions.
IntActP47131. 2 interactions.
MINTMINT-4491887.
STRING4932.YJR085C.

Proteomic databases

PaxDbP47131.
PeptideAtlasP47131.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYJR085C; YJR085C; YJR085C.
GeneID853547.
KEGGsce:YJR085C.

Organism-specific databases

CYGDYJR085c.
SGDS000003845. YJR085C.

Phylogenomic databases

eggNOGCOG5548.
HOGENOMHOG000211932.
OMAYAGYLLK.
OrthoDBEOG78D7ZJ.

Enzyme and pathway databases

BioCycYEAST:G3O-31713-MONOMER.

Gene expression databases

GenevestigatorP47131.

Family and domain databases

InterProIPR005349. UPF0136_TM.
[Graphical view]
PANTHERPTHR12668. PTHR12668. 1 hit.
PfamPF03647. Tmemb_14. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio974275.

Entry information

Entry nameYJ55_YEAST
AccessionPrimary (citable) accession number: P47131
Secondary accession number(s): D6VWQ4
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: March 19, 2014
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome X

Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

Uncharacterized protein families (UPF)

List of uncharacterized protein family (UPF) entries

SIMILARITY comments

Index of protein domains and families