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P47131

- YJ55_YEAST

UniProt

P47131 - YJ55_YEAST

Protein

UPF0136 membrane protein YJR085C

Gene

YJR085C

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
  1. Functioni

    Enzyme and pathway databases

    BioCyciYEAST:G3O-31713-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    UPF0136 membrane protein YJR085C
    Gene namesi
    Ordered Locus Names:YJR085C
    ORF Names:J1863
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome X

    Organism-specific databases

    CYGDiYJR085c.
    SGDiS000003845. YJR085C.

    Subcellular locationi

    Mitochondrion 2 Publications. Membrane Curated; Multi-pass membrane protein Curated

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. mitochondrion Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Membrane, Mitochondrion

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 105105UPF0136 membrane protein YJR085CPRO_0000203105Add
    BLAST

    Proteomic databases

    MaxQBiP47131.
    PaxDbiP47131.
    PeptideAtlasiP47131.

    Expressioni

    Inductioni

    By the DNA-damaging agent methyl methanesulphonate (MMS) (at protein level).1 Publication

    Gene expression databases

    GenevestigatoriP47131.

    Interactioni

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    TSA2Q041201EBI-25560,EBI-19631

    Protein-protein interaction databases

    BioGridi33840. 6 interactions.
    IntActiP47131. 2 interactions.
    MINTiMINT-4491887.
    STRINGi4932.YJR085C.

    Structurei

    3D structure databases

    ProteinModelPortaliP47131.
    SMRiP47131. Positions 1-104.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei26 – 4621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei53 – 7321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei77 – 9721HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the UPF0136 (TMEM14) family.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG5548.
    HOGENOMiHOG000211932.
    OMAiYAGYLLK.
    OrthoDBiEOG78D7ZJ.

    Family and domain databases

    InterProiIPR005349. UPF0136_TM.
    [Graphical view]
    PANTHERiPTHR12668. PTHR12668. 1 hit.
    PfamiPF03647. Tmemb_14. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P47131-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEHPAYTLSL LTTAGGLMGY YRKGSIPSLV SGLVFGSVYG IAGYLLHMNR    50
    DGGLEMALGA STLLLGAGVI RGMPSRFTKP VPVVLTALGG LGSYYYYNKY 100
    KEFYP 105
    Length:105
    Mass (Da):11,250
    Last modified:February 1, 1996 - v1
    Checksum:iC35A1E8AB98CFFA0
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z49585 Genomic DNA. Translation: CAA89612.1.
    L47993 Genomic DNA. Translation: AAB39308.1.
    AY557887 Genomic DNA. Translation: AAS56213.1.
    BK006943 Genomic DNA. Translation: DAA08870.1.
    PIRiS57104.
    RefSeqiNP_012618.3. NM_001181742.3.

    Genome annotation databases

    EnsemblFungiiYJR085C; YJR085C; YJR085C.
    GeneIDi853547.
    KEGGisce:YJR085C.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z49585 Genomic DNA. Translation: CAA89612.1 .
    L47993 Genomic DNA. Translation: AAB39308.1 .
    AY557887 Genomic DNA. Translation: AAS56213.1 .
    BK006943 Genomic DNA. Translation: DAA08870.1 .
    PIRi S57104.
    RefSeqi NP_012618.3. NM_001181742.3.

    3D structure databases

    ProteinModelPortali P47131.
    SMRi P47131. Positions 1-104.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 33840. 6 interactions.
    IntActi P47131. 2 interactions.
    MINTi MINT-4491887.
    STRINGi 4932.YJR085C.

    Proteomic databases

    MaxQBi P47131.
    PaxDbi P47131.
    PeptideAtlasi P47131.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YJR085C ; YJR085C ; YJR085C .
    GeneIDi 853547.
    KEGGi sce:YJR085C.

    Organism-specific databases

    CYGDi YJR085c.
    SGDi S000003845. YJR085C.

    Phylogenomic databases

    eggNOGi COG5548.
    HOGENOMi HOG000211932.
    OMAi YAGYLLK.
    OrthoDBi EOG78D7ZJ.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-31713-MONOMER.

    Miscellaneous databases

    NextBioi 974275.

    Gene expression databases

    Genevestigatori P47131.

    Family and domain databases

    InterProi IPR005349. UPF0136_TM.
    [Graphical view ]
    PANTHERi PTHR12668. PTHR12668. 1 hit.
    Pfami PF03647. Tmemb_14. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Analysis of a 62 kb DNA sequence of chromosome X reveals 36 open reading frames and a gene cluster with a counterpart on chromosome XI."
      Huang M.-E., Manus V., Chuat J.-C., Galibert F.
      Yeast 12:869-875(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."
      Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K.
      , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.
      EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    3. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    4. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    5. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
    6. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
      Strain: ATCC 76625 / YPH499.
    7. "Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics."
      Reinders J., Zahedi R.P., Pfanner N., Meisinger C., Sickmann A.
      J. Proteome Res. 5:1543-1554(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    8. "Global protein expression profiling of budding yeast in response to DNA damage."
      Lee M.-W., Kim B.-J., Choi H.-K., Ryu M.-J., Kim S.-B., Kang K.-M., Cho E.-J., Youn H.-D., Huh W.-K., Kim S.-T.
      Yeast 24:145-154(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: INDUCTION.

    Entry informationi

    Entry nameiYJ55_YEAST
    AccessioniPrimary (citable) accession number: P47131
    Secondary accession number(s): D6VWQ4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1996
    Last sequence update: February 1, 1996
    Last modified: October 1, 2014
    This is version 100 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Present with 2100 molecules/cell in log phase SD medium.1 Publication

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Uncharacterized protein families (UPF)
      List of uncharacterized protein family (UPF) entries
    3. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    4. Yeast chromosome X
      Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

    External Data

    Dasty 3