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P47131

- YJ55_YEAST

UniProt

P47131 - YJ55_YEAST

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Protein

UPF0136 membrane protein YJR085C

Gene

YJR085C

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciYEAST:G3O-31713-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0136 membrane protein YJR085C
Gene namesi
Ordered Locus Names:YJR085C
ORF Names:J1863
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome X

Organism-specific databases

CYGDiYJR085c.
SGDiS000003845. YJR085C.

Subcellular locationi

Mitochondrion 2 Publications. Membrane Curated; Multi-pass membrane protein Curated

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. mitochondrion Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 105105UPF0136 membrane protein YJR085CPRO_0000203105Add
BLAST

Proteomic databases

MaxQBiP47131.
PaxDbiP47131.
PeptideAtlasiP47131.

Expressioni

Inductioni

By the DNA-damaging agent methyl methanesulphonate (MMS) (at protein level).1 Publication

Gene expression databases

GenevestigatoriP47131.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
TSA2Q041201EBI-25560,EBI-19631

Protein-protein interaction databases

BioGridi33840. 7 interactions.
IntActiP47131. 2 interactions.
MINTiMINT-4491887.
STRINGi4932.YJR085C.

Structurei

3D structure databases

ProteinModelPortaliP47131.
SMRiP47131. Positions 1-104.
ModBaseiSearch...
MobiDBiSearch...

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei26 – 4621HelicalSequence AnalysisAdd
BLAST
Transmembranei53 – 7321HelicalSequence AnalysisAdd
BLAST
Transmembranei77 – 9721HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0136 (TMEM14) family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG5548.
HOGENOMiHOG000211932.
InParanoidiP47131.
OMAiYAGYLLK.
OrthoDBiEOG78D7ZJ.

Family and domain databases

InterProiIPR005349. UPF0136_TM.
[Graphical view]
PANTHERiPTHR12668. PTHR12668. 1 hit.
PfamiPF03647. Tmemb_14. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P47131-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEHPAYTLSL LTTAGGLMGY YRKGSIPSLV SGLVFGSVYG IAGYLLHMNR
60 70 80 90 100
DGGLEMALGA STLLLGAGVI RGMPSRFTKP VPVVLTALGG LGSYYYYNKY

KEFYP
Length:105
Mass (Da):11,250
Last modified:February 1, 1996 - v1
Checksum:iC35A1E8AB98CFFA0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z49585 Genomic DNA. Translation: CAA89612.1.
L47993 Genomic DNA. Translation: AAB39308.1.
AY557887 Genomic DNA. Translation: AAS56213.1.
BK006943 Genomic DNA. Translation: DAA08870.1.
PIRiS57104.
RefSeqiNP_012618.3. NM_001181742.3.

Genome annotation databases

EnsemblFungiiYJR085C; YJR085C; YJR085C.
GeneIDi853547.
KEGGisce:YJR085C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z49585 Genomic DNA. Translation: CAA89612.1 .
L47993 Genomic DNA. Translation: AAB39308.1 .
AY557887 Genomic DNA. Translation: AAS56213.1 .
BK006943 Genomic DNA. Translation: DAA08870.1 .
PIRi S57104.
RefSeqi NP_012618.3. NM_001181742.3.

3D structure databases

ProteinModelPortali P47131.
SMRi P47131. Positions 1-104.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 33840. 7 interactions.
IntActi P47131. 2 interactions.
MINTi MINT-4491887.
STRINGi 4932.YJR085C.

Proteomic databases

MaxQBi P47131.
PaxDbi P47131.
PeptideAtlasi P47131.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YJR085C ; YJR085C ; YJR085C .
GeneIDi 853547.
KEGGi sce:YJR085C.

Organism-specific databases

CYGDi YJR085c.
SGDi S000003845. YJR085C.

Phylogenomic databases

eggNOGi COG5548.
HOGENOMi HOG000211932.
InParanoidi P47131.
OMAi YAGYLLK.
OrthoDBi EOG78D7ZJ.

Enzyme and pathway databases

BioCyci YEAST:G3O-31713-MONOMER.

Miscellaneous databases

NextBioi 974275.

Gene expression databases

Genevestigatori P47131.

Family and domain databases

InterProi IPR005349. UPF0136_TM.
[Graphical view ]
PANTHERi PTHR12668. PTHR12668. 1 hit.
Pfami PF03647. Tmemb_14. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Analysis of a 62 kb DNA sequence of chromosome X reveals 36 open reading frames and a gene cluster with a counterpart on chromosome XI."
    Huang M.-E., Manus V., Chuat J.-C., Galibert F.
    Yeast 12:869-875(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."
    Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K.
    , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.
    EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  4. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  5. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  6. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    Strain: ATCC 76625 / YPH499.
  7. "Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics."
    Reinders J., Zahedi R.P., Pfanner N., Meisinger C., Sickmann A.
    J. Proteome Res. 5:1543-1554(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  8. "Global protein expression profiling of budding yeast in response to DNA damage."
    Lee M.-W., Kim B.-J., Choi H.-K., Ryu M.-J., Kim S.-B., Kang K.-M., Cho E.-J., Youn H.-D., Huh W.-K., Kim S.-T.
    Yeast 24:145-154(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: INDUCTION.

Entry informationi

Entry nameiYJ55_YEAST
AccessioniPrimary (citable) accession number: P47131
Secondary accession number(s): D6VWQ4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: October 29, 2014
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 2100 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  4. Yeast chromosome X
    Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

External Data

Dasty 3