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P47129 (ACF4_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 94. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Assembly-complementing factor 4
Gene names
Name:ACF4
Ordered Locus Names:YJR083C
ORF Names:J1857
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length309 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

May be involved in actin cytoskeleton organization and biogenesis. Ref.6

Miscellaneous

Present with 1140 molecules/cell in log phase SD medium.

Binary interactions

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 309309Assembly-complementing factor 4
PRO_0000203104

Amino acid modifications

Modified residue441Phosphoserine Ref.8
Modified residue711Phosphoserine Ref.7 Ref.9
Modified residue741Phosphoserine Ref.7 Ref.9 Ref.10
Modified residue781Phosphoserine Ref.7 Ref.10
Modified residue1651Phosphoserine Ref.7 Ref.9 Ref.10
Modified residue2881Phosphoserine Ref.7 Ref.9 Ref.10

Sequences

Sequence LengthMass (Da)Tools
P47129 [UniParc].

Last modified February 1, 1996. Version 1.
Checksum: FE29E8D0192B2113

FASTA30935,521
        10         20         30         40         50         60 
MSEDQRVISQ PIELHKLSIV DKHSQGQQQQ PHQKQHEVQP ESKSPRVTTP LKPKRLAIPI 

        70         80         90        100        110        120 
SSPQRSTTNQ SPVSDHASPI STDQDLIYKL AAKHREINEL SFKLEVAQKE LKQLELQFKD 

       130        140        150        160        170        180 
TLPRNGQQKL GNQNPSEYLS TFTKRIQQTF VDVNNSPNML KGKKSINDFF SKPNNNVNSN 

       190        200        210        220        230        240 
INNTLPNRKP NPPPNRSQRM QNIAPSRSSE STPTSGPPLL PPRNTMKNAN TTATAGENTP 

       250        260        270        280        290        300 
FLQRILNKFN QMNMEEDEFD DLLEKRKSKK DHYYIKENLG YEYDEVRSED EDDEEFEPMG 


DIPVHLFKR 

« Hide

References

« Hide 'large scale' references
[1]"Analysis of a 62 kb DNA sequence of chromosome X reveals 36 open reading frames and a gene cluster with a counterpart on chromosome XI."
Huang M.-E., Manus V., Chuat J.-C., Galibert F.
Yeast 12:869-875(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."
Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K. expand/collapse author list , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.
EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[5]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[6]"Predicting protein functions from redundancies in large-scale protein interaction networks."
Samanta M.P., Liang S.
Proc. Natl. Acad. Sci. U.S.A. 100:12579-12583(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION PREDICTION.
[7]"Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae."
Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J., Elias J.E., Gygi S.P.
J. Proteome Res. 6:1190-1197(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-71; SER-74; SER-78; SER-165 AND SER-288, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Strain: ADR376.
[8]"Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry."
Chi A., Huttenhower C., Geer L.Y., Coon J.J., Syka J.E.P., Bai D.L., Shabanowitz J., Burke D.J., Troyanskaya O.G., Hunt D.F.
Proc. Natl. Acad. Sci. U.S.A. 104:2193-2198(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-44, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[9]"A multidimensional chromatography technology for in-depth phosphoproteome analysis."
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-71; SER-74; SER-165 AND SER-288, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[10]"Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-74; SER-78; SER-165 AND SER-288, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z49583 Genomic DNA. Translation: CAA89610.1.
L47993 Genomic DNA. Translation: AAB39306.1.
AY557912 Genomic DNA. Translation: AAS56238.1.
BK006943 Genomic DNA. Translation: DAA08868.1.
PIRS57102.
RefSeqNP_012616.1. NM_001181740.1.

3D structure databases

ProteinModelPortalP47129.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid33838. 23 interactions.
DIPDIP-2890N.
IntActP47129. 8 interactions.
MINTMINT-399509.
STRING4932.YJR083C.

Proteomic databases

MaxQBP47129.
PaxDbP47129.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYJR083C; YJR083C; YJR083C.
GeneID853545.
KEGGsce:YJR083C.

Organism-specific databases

CYGDYJR083c.
SGDS000003843. ACF4.

Phylogenomic databases

eggNOGNOG68626.
OMAKHREINE.
OrthoDBEOG7P2Z44.

Enzyme and pathway databases

BioCycYEAST:G3O-31711-MONOMER.

Gene expression databases

GenevestigatorP47129.

Family and domain databases

ProtoNetSearch...

Other

NextBio974269.

Entry information

Entry nameACF4_YEAST
AccessionPrimary (citable) accession number: P47129
Secondary accession number(s): D6VWQ2
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: June 11, 2014
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome X

Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD