Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P47129

- ACF4_YEAST

UniProt

P47129 - ACF4_YEAST

Protein

Assembly-complementing factor 4

Gene

ACF4

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 95 (01 Oct 2014)
      Sequence version 1 (01 Feb 1996)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    May be involved in actin cytoskeleton organization and biogenesis.1 Publication

    GO - Molecular functioni

    1. protein binding Source: IntAct

    Enzyme and pathway databases

    BioCyciYEAST:G3O-31711-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Assembly-complementing factor 4
    Gene namesi
    Name:ACF4
    Ordered Locus Names:YJR083C
    ORF Names:J1857
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome X

    Organism-specific databases

    CYGDiYJR083c.
    SGDiS000003843. ACF4.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 309309Assembly-complementing factor 4PRO_0000203104Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei44 – 441Phosphoserine1 Publication
    Modified residuei71 – 711Phosphoserine2 Publications
    Modified residuei74 – 741Phosphoserine3 Publications
    Modified residuei78 – 781Phosphoserine2 Publications
    Modified residuei165 – 1651Phosphoserine3 Publications
    Modified residuei288 – 2881Phosphoserine3 Publications

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    MaxQBiP47129.
    PaxDbiP47129.

    Expressioni

    Gene expression databases

    GenevestigatoriP47129.

    Interactioni

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    LSB3P436034EBI-25556,EBI-22980
    RVS167P397435EBI-25556,EBI-14500
    YSC84P327934EBI-25556,EBI-24460

    Protein-protein interaction databases

    BioGridi33838. 23 interactions.
    DIPiDIP-2890N.
    IntActiP47129. 8 interactions.
    MINTiMINT-399509.
    STRINGi4932.YJR083C.

    Structurei

    3D structure databases

    ProteinModelPortaliP47129.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiNOG68626.
    OMAiKHREINE.
    OrthoDBiEOG7P2Z44.

    Sequencei

    Sequence statusi: Complete.

    P47129-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSEDQRVISQ PIELHKLSIV DKHSQGQQQQ PHQKQHEVQP ESKSPRVTTP    50
    LKPKRLAIPI SSPQRSTTNQ SPVSDHASPI STDQDLIYKL AAKHREINEL 100
    SFKLEVAQKE LKQLELQFKD TLPRNGQQKL GNQNPSEYLS TFTKRIQQTF 150
    VDVNNSPNML KGKKSINDFF SKPNNNVNSN INNTLPNRKP NPPPNRSQRM 200
    QNIAPSRSSE STPTSGPPLL PPRNTMKNAN TTATAGENTP FLQRILNKFN 250
    QMNMEEDEFD DLLEKRKSKK DHYYIKENLG YEYDEVRSED EDDEEFEPMG 300
    DIPVHLFKR 309
    Length:309
    Mass (Da):35,521
    Last modified:February 1, 1996 - v1
    Checksum:iFE29E8D0192B2113
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z49583 Genomic DNA. Translation: CAA89610.1.
    L47993 Genomic DNA. Translation: AAB39306.1.
    AY557912 Genomic DNA. Translation: AAS56238.1.
    BK006943 Genomic DNA. Translation: DAA08868.1.
    PIRiS57102.
    RefSeqiNP_012616.1. NM_001181740.1.

    Genome annotation databases

    EnsemblFungiiYJR083C; YJR083C; YJR083C.
    GeneIDi853545.
    KEGGisce:YJR083C.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z49583 Genomic DNA. Translation: CAA89610.1 .
    L47993 Genomic DNA. Translation: AAB39306.1 .
    AY557912 Genomic DNA. Translation: AAS56238.1 .
    BK006943 Genomic DNA. Translation: DAA08868.1 .
    PIRi S57102.
    RefSeqi NP_012616.1. NM_001181740.1.

    3D structure databases

    ProteinModelPortali P47129.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 33838. 23 interactions.
    DIPi DIP-2890N.
    IntActi P47129. 8 interactions.
    MINTi MINT-399509.
    STRINGi 4932.YJR083C.

    Proteomic databases

    MaxQBi P47129.
    PaxDbi P47129.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YJR083C ; YJR083C ; YJR083C .
    GeneIDi 853545.
    KEGGi sce:YJR083C.

    Organism-specific databases

    CYGDi YJR083c.
    SGDi S000003843. ACF4.

    Phylogenomic databases

    eggNOGi NOG68626.
    OMAi KHREINE.
    OrthoDBi EOG7P2Z44.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-31711-MONOMER.

    Miscellaneous databases

    NextBioi 974269.

    Gene expression databases

    Genevestigatori P47129.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Analysis of a 62 kb DNA sequence of chromosome X reveals 36 open reading frames and a gene cluster with a counterpart on chromosome XI."
      Huang M.-E., Manus V., Chuat J.-C., Galibert F.
      Yeast 12:869-875(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."
      Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K.
      , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.
      EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    3. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    4. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    5. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
    6. "Predicting protein functions from redundancies in large-scale protein interaction networks."
      Samanta M.P., Liang S.
      Proc. Natl. Acad. Sci. U.S.A. 100:12579-12583(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION PREDICTION.
    7. "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae."
      Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J., Elias J.E., Gygi S.P.
      J. Proteome Res. 6:1190-1197(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-71; SER-74; SER-78; SER-165 AND SER-288, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Strain: ADR376.
    8. "Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry."
      Chi A., Huttenhower C., Geer L.Y., Coon J.J., Syka J.E.P., Bai D.L., Shabanowitz J., Burke D.J., Troyanskaya O.G., Hunt D.F.
      Proc. Natl. Acad. Sci. U.S.A. 104:2193-2198(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-44, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    9. "A multidimensional chromatography technology for in-depth phosphoproteome analysis."
      Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
      Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-71; SER-74; SER-165 AND SER-288, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    10. "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
      Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
      Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-74; SER-78; SER-165 AND SER-288, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiACF4_YEAST
    AccessioniPrimary (citable) accession number: P47129
    Secondary accession number(s): D6VWQ2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1996
    Last sequence update: February 1, 1996
    Last modified: October 1, 2014
    This is version 95 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Present with 1140 molecules/cell in log phase SD medium.1 Publication

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    2. Yeast chromosome X
      Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

    External Data

    Dasty 3