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Protein

Nuclear import protein MOG1

Gene

MOG1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in the Ran-GTPase system for nuclear protein import and poly(A)+ mRNA export.2 Publications

Miscellaneous

Present with 2840 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

  • Ran GTPase binding Source: SGD

GO - Biological processi

  • mRNA transport Source: UniProtKB-KW
  • protein import into nucleus Source: SGD

Keywordsi

Biological processmRNA transport, Protein transport, Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-31705-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Nuclear import protein MOG1
Alternative name(s):
Multicopy suppressor of GSP1
Gene namesi
Name:MOG1
Ordered Locus Names:YJR074W
ORF Names:J1827
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome X

Organism-specific databases

EuPathDBiFungiDB:YJR074W
SGDiS000003835 MOG1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002152031 – 218Nuclear import protein MOG1Add BLAST218

Proteomic databases

MaxQBiP47123
PaxDbiP47123
PRIDEiP47123

Interactioni

Subunit structurei

Interacts with GSP1.1 Publication

Binary interactionsi

WithEntry#Exp.IntActNotes
GSP2P328363EBI-11145,EBI-7934

GO - Molecular functioni

  • Ran GTPase binding Source: SGD

Protein-protein interaction databases

BioGridi33830, 463 interactors
DIPiDIP-1356N
IntActiP47123, 5 interactors
MINTiP47123
STRINGi4932.YJR074W

Structurei

Secondary structure

1218
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi34 – 38Combined sources5
Helixi39 – 41Combined sources3
Beta strandi43 – 47Combined sources5
Beta strandi51 – 53Combined sources3
Helixi54 – 56Combined sources3
Beta strandi64 – 69Combined sources6
Beta strandi78 – 80Combined sources3
Beta strandi86 – 93Combined sources8
Helixi100 – 112Combined sources13
Helixi113 – 115Combined sources3
Beta strandi117 – 129Combined sources13
Turni130 – 132Combined sources3
Beta strandi133 – 143Combined sources11
Beta strandi154 – 163Combined sources10
Helixi164 – 166Combined sources3
Beta strandi168 – 177Combined sources10
Helixi180 – 186Combined sources7
Turni187 – 189Combined sources3
Helixi193 – 207Combined sources15
Beta strandi210 – 212Combined sources3
Helixi214 – 216Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1EQ6X-ray1.90A30-218[»]
1JHSX-ray1.90A31-218[»]
ProteinModelPortaliP47123
SMRiP47123
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP47123

Family & Domainsi

Sequence similaritiesi

Belongs to the MOG1 family.Curated

Phylogenomic databases

GeneTreeiENSGT00390000013834
HOGENOMiHOG000247047
InParanoidiP47123
OMAiHMEDIAD
OrthoDBiEOG092C4NQG

Family and domain databases

CDDicd00224 Mog1, 1 hit
Gene3Di3.40.1000.10, 1 hit
InterProiView protein in InterPro
IPR007681 Mog1
IPR016123 Mog1/PsbP_a/b/a-sand
PANTHERiPTHR15837 PTHR15837, 1 hit
PfamiView protein in Pfam
PF04603 Mog1, 1 hit
SUPFAMiSSF55724 SSF55724, 1 hit

Sequencei

Sequence statusi: Complete.

P47123-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIEKASHIS QPVQLSTCTL IDTYPGHQGS MNNKEVELYG GAITTVVPPG
60 70 80 90 100
FIDASTLREV PDTQEVYVNS RRDEEEFEDG LATNESIIVD LLETVDKSDL
110 120 130 140 150
KEAWQFHVED LTELNGTTKW EALQEDTVQQ GTKFTGLVME VANKWGKPDL
160 170 180 190 200
AQTVVIGVAL IRLTQFDTDV VISINVPLTK EEASQASNKE LPARCHAVYQ
210
LLQEMVRKFH VVDTSLFA
Length:218
Mass (Da):24,307
Last modified:February 1, 1996 - v1
Checksum:i980156FF01A1542D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB015285 Genomic DNA Translation: BAA28825.1
L47993 Genomic DNA Translation: AAB39299.1
Z49574 Genomic DNA Translation: CAA89602.1
BK006943 Genomic DNA Translation: DAA08860.1
PIRiS57093
RefSeqiNP_012608.1, NM_001181732.1

Genome annotation databases

EnsemblFungiiYJR074W; YJR074W; YJR074W
GeneIDi853537
KEGGisce:YJR074W

Similar proteinsi

Entry informationi

Entry nameiMOG1_YEAST
AccessioniPrimary (citable) accession number: P47123
Secondary accession number(s): D6VWP4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: March 28, 2018
This is version 142 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome
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Main funding by: National Institutes of Health