P47118 (YAE1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein YAE1

Gene names

Name:	YAE1
Ordered Locus Names:	YJR067C
ORF Names:	J1805

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae

Protein attributes

Sequence length	141 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location	Cytoplasm. Nucleus Ref.5.
Miscellaneous	Present with 1500 molecules/cell in log phase SD medium.
Sequence similarities	Belongs to the YAE1 family.

Ontologies

Keywords
Cellular component	Cytoplasm Nucleus
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	ribosomal large subunit biogenesis Inferred from physical interaction PubMed 23318452. Source: SGD translational initiation Inferred from physical interaction PubMed 23318452. Source: SGD
Cellular_component	cytoplasm Inferred from direct assay Ref.5. Source: SGD nucleus Inferred from direct assay Ref.5. Source: SGD
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
YNL260C	P53846	2	EBI-25522,EBI-28226

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 141	141	Uncharacterized protein YAE1		PRO_0000203099

Sequences

	Sequence		Length	Mass (Da)
	P47118 [UniParc]. Last modified February 1, 1996. Version 1. Checksum: AD0D90D51C03C996	FASTA	141	16,076
	10 20 30 40 50 60 MSNTWDDVWA SDSDVETERS PDLVKLRENH SKRGYLDGIV SSKEEKLQEG FNDGFPTGAK 70 80 90 100 110 120 LGKQVGIIMG ILLGLRTRFG DEDEDLSKAY IDAQKELRIN KVLSKSIFDP NFDLQEKHPL 130 140 ITKWTDIANT YCEKYHVPSI Q

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Analysis of a 62 kb DNA sequence of chromosome X reveals 36 open reading frames and a gene cluster with a counterpart on chromosome XI." Huang M.-E., Manus V., Chuat J.-C., Galibert F. Yeast 12:869-875(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[2]	"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X." Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K. , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L. EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679.
[3]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[4]	"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J. Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[5]	"Global analysis of protein localization in budding yeast." Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K. Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[6]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z49567 Genomic DNA. Translation: CAA89595.1. L47993 Genomic DNA. Translation: AAB39293.1. AY557892 Genomic DNA. Translation: AAS56218.1. BK006943 Genomic DNA. Translation: DAA08854.1.
PIR	S57086.
RefSeq	NP_012601.1. NM_001181725.1.
3D structure databases
ProteinModelPortal	P47118.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-5706N.
IntAct	P47118. 1 interaction.
MINT	MINT-566734.
STRING	4932.YJR067C.
Proteomic databases
PaxDb	P47118.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YJR067C; YJR067C; YJR067C.
GeneID	853530.
KEGG	sce:YJR067C.
Organism-specific databases
CYGD	YJR067c.
SGD	S000003828. YAE1.
Phylogenomic databases
eggNOG	NOG253004.
HOGENOM	HOG000066088.
OMA	HSKRGYL.
OrthoDB	EOG479JHC.
Gene expression databases
Genevestigator	P47118.
GermOnline	YJR067C. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR019191. Essential_protein_Yae1_N. [Graphical view]
Pfam	PF09811. Yae1_N. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	974227.

Entry information

Entry name

YAE1_YEAST

Accession

Primary (citable) accession number: P47118
Secondary accession number(s): D6VWN8

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1996
Last sequence update:	February 1, 1996
Last modified:	April 3, 2013
This is version 86 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program