Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Vacuolar protein sorting-associated protein 55

Gene

VPS55

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Involved in protein transport from endosomes to the vacuole.1 Publication

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-31679-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Vacuolar protein sorting-associated protein 55
Gene namesi
Name:VPS55
Ordered Locus Names:YJR044C
ORF Names:J1637
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome X

Organism-specific databases

EuPathDBiFungiDB:YJR044C.
SGDiS000003805. VPS55.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 11CytoplasmicSequence analysisAdd BLAST11
Transmembranei12 – 32HelicalSequence analysisAdd BLAST21
Topological domaini33 – 37LumenalSequence analysis5
Transmembranei38 – 58HelicalSequence analysisAdd BLAST21
Topological domaini59 – 76CytoplasmicSequence analysisAdd BLAST18
Transmembranei77 – 97HelicalSequence analysisAdd BLAST21
Topological domaini98 – 107LumenalSequence analysis10
Transmembranei108 – 128HelicalSequence analysisAdd BLAST21
Topological domaini129 – 140CytoplasmicSequence analysisAdd BLAST12

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • late endosome Source: SGD
  • Vps55/Vps68 complex Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Endosome, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002152011 – 140Vacuolar protein sorting-associated protein 55Add BLAST140

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei137PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiP47111.

PTM databases

iPTMnetiP47111.

Interactioni

Protein-protein interaction databases

BioGridi33796. 89 interactors.
DIPiDIP-7667N.
IntActiP47111. 3 interactors.
MINTiMINT-485094.

Structurei

3D structure databases

ProteinModelPortaliP47111.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the OB-RGRP/VPS55 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00390000006503.
HOGENOMiHOG000038515.
InParanoidiP47111.
OMAiYNFLTFN.
OrthoDBiEOG092C5H4M.

Family and domain databases

InterProiIPR007262. VPS55.
[Graphical view]
PANTHERiPTHR12050. PTHR12050. 1 hit.
PfamiPF04133. Vps55. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P47111-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMEFKVSPLT KIISLSGFLA LGFLLVILSC ALFHNYYPLF DILIFLLAPI
60 70 80 90 100
PNTIFNAGNK YHTSDFMSDS SNTGQDLAHF LTGMLVTSGI ALPVVFYHCQ
110 120 130 140
LIGHLSCIMC MIGGLIIYSS IVIFKWFFKK DFNEDDSLFG
Length:140
Mass (Da):15,664
Last modified:February 1, 1996 - v1
Checksum:i1F207E62F093FC6D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49544 Genomic DNA. Translation: CAA89572.1.
L36344 Genomic DNA. Translation: AAA88746.1.
AY557891 Genomic DNA. Translation: AAS56217.1.
BK006943 Genomic DNA. Translation: DAA08831.1.
PIRiS57063.
RefSeqiNP_012578.3. NM_001181702.3.

Genome annotation databases

EnsemblFungiiYJR044C; YJR044C; YJR044C.
GeneIDi853502.
KEGGisce:YJR044C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49544 Genomic DNA. Translation: CAA89572.1.
L36344 Genomic DNA. Translation: AAA88746.1.
AY557891 Genomic DNA. Translation: AAS56217.1.
BK006943 Genomic DNA. Translation: DAA08831.1.
PIRiS57063.
RefSeqiNP_012578.3. NM_001181702.3.

3D structure databases

ProteinModelPortaliP47111.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi33796. 89 interactors.
DIPiDIP-7667N.
IntActiP47111. 3 interactors.
MINTiMINT-485094.

PTM databases

iPTMnetiP47111.

Proteomic databases

PRIDEiP47111.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYJR044C; YJR044C; YJR044C.
GeneIDi853502.
KEGGisce:YJR044C.

Organism-specific databases

EuPathDBiFungiDB:YJR044C.
SGDiS000003805. VPS55.

Phylogenomic databases

GeneTreeiENSGT00390000006503.
HOGENOMiHOG000038515.
InParanoidiP47111.
OMAiYNFLTFN.
OrthoDBiEOG092C5H4M.

Enzyme and pathway databases

BioCyciYEAST:G3O-31679-MONOMER.

Miscellaneous databases

PROiP47111.

Family and domain databases

InterProiIPR007262. VPS55.
[Graphical view]
PANTHERiPTHR12050. PTHR12050. 1 hit.
PfamiPF04133. Vps55. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiVPS55_YEAST
AccessioniPrimary (citable) accession number: P47111
Secondary accession number(s): D6VWL5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: November 30, 2016
This is version 120 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 2340 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome X
    Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.