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Protein

Vacuolar protein sorting-associated protein 55

Gene

VPS55

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in protein transport from endosomes to the vacuole.1 Publication

Miscellaneous

Present with 2340 molecules/cell in log phase SD medium.1 Publication

GO - Biological processi

Keywordsi

Biological processProtein transport, Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-31679-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Vacuolar protein sorting-associated protein 55
Gene namesi
Name:VPS55
Ordered Locus Names:YJR044C
ORF Names:J1637
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome X

Organism-specific databases

EuPathDBiFungiDB:YJR044C
SGDiS000003805 VPS55

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 11CytoplasmicSequence analysisAdd BLAST11
Transmembranei12 – 32HelicalSequence analysisAdd BLAST21
Topological domaini33 – 37LumenalSequence analysis5
Transmembranei38 – 58HelicalSequence analysisAdd BLAST21
Topological domaini59 – 76CytoplasmicSequence analysisAdd BLAST18
Transmembranei77 – 97HelicalSequence analysisAdd BLAST21
Topological domaini98 – 107LumenalSequence analysis10
Transmembranei108 – 128HelicalSequence analysisAdd BLAST21
Topological domaini129 – 140CytoplasmicSequence analysisAdd BLAST12

Keywords - Cellular componenti

Endosome, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002152011 – 140Vacuolar protein sorting-associated protein 55Add BLAST140

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei137PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP47111
PRIDEiP47111

PTM databases

iPTMnetiP47111

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
VPS68Q120163EBI-25497,EBI-29309

Protein-protein interaction databases

BioGridi33796, 209 interactors
DIPiDIP-7667N
IntActiP47111, 4 interactors
STRINGi4932.YJR044C

Structurei

3D structure databases

ProteinModelPortaliP47111
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the OB-RGRP/VPS55 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000038515
InParanoidiP47111
OMAiVIEWGAC
OrthoDBiEOG092C5H4M

Family and domain databases

InterProiView protein in InterPro
IPR007262 VPS55
PANTHERiPTHR12050 PTHR12050, 1 hit
PfamiView protein in Pfam
PF04133 Vps55, 1 hit

Sequencei

Sequence statusi: Complete.

P47111-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMEFKVSPLT KIISLSGFLA LGFLLVILSC ALFHNYYPLF DILIFLLAPI
60 70 80 90 100
PNTIFNAGNK YHTSDFMSDS SNTGQDLAHF LTGMLVTSGI ALPVVFYHCQ
110 120 130 140
LIGHLSCIMC MIGGLIIYSS IVIFKWFFKK DFNEDDSLFG
Length:140
Mass (Da):15,664
Last modified:February 1, 1996 - v1
Checksum:i1F207E62F093FC6D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49544 Genomic DNA Translation: CAA89572.1
L36344 Genomic DNA Translation: AAA88746.1
AY557891 Genomic DNA Translation: AAS56217.1
BK006943 Genomic DNA Translation: DAA08831.1
PIRiS57063
RefSeqiNP_012578.3, NM_001181702.3

Genome annotation databases

EnsemblFungiiYJR044C; YJR044C; YJR044C
GeneIDi853502
KEGGisce:YJR044C

Similar proteinsi

Entry informationi

Entry nameiVPS55_YEAST
AccessioniPrimary (citable) accession number: P47111
Secondary accession number(s): D6VWL5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: May 23, 2018
This is version 130 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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