P47101 (YJ00_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
UPF0508 protein YJR030C

Gene names

Ordered Locus Names:	YJR030C
ORF Names:	J1575L

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae

Protein attributes

Sequence length	745 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities	Belongs to the UPF0508 family.
Caution	This is a truncated version of an UPF0508 family protein. Strain S288c has a tandem insertion of a Ty1 transposon in position 742, which disrupts the gene coding for this protein and produces two ORFs YJR030C and YJR025C-A. A contiguous sequence of this protein can be found in strain YJM789 (AC A6ZPZ1).
Sequence caution	The sequence CAA60727.1 differs from that shown. Reason: Contains PCR fragment of strain VP102-10A.

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 745	745	UPF0508 protein YJR030C		PRO_0000203090
Regions
	Compositional bias	680 – 736	57	Ser-rich
Natural variations
	Natural variant	742 – 745	4	LRNM → HVKTKADVWKPSRVGYTDIF SQEYKGIVVAIKFVICSDAE GTLYPREYNSRLHDIKRLGR TGLSFTDKKEAYLLEFKNQD VVDHVHKLILPFNTSWQSN in strain: VP102-10A.

Sequences

	Sequence		Length	Mass (Da)
	P47101 [UniParc]. Last modified November 2, 2010. Version 3. Checksum: B287BC72FCE6A211	FASTA	745	84,290
	10 20 30 40 50 60 MELFNKEEAS FETLLKRLLV VCESHSRYHG SSLDPMVKVG HEMRKISGYL RCILRKHAAN 70 80 90 100 110 120 HDDMSLTQSI VNSYKSLFKD AQILDLYHNL LFGCMHLLLD ANMSYFRMDS QKLFAVLLFK 130 140 150 160 170 180 VYYKLRDIFY VTNEVRLGSL ISAFVYKFKS CYDFISCNSL KYGSVRDVIS GEVSLINLPP 190 200 210 220 230 240 IDSNKVINRA YYRLDVKKLA INNKLVEILE LDNGEIAIFE VLSEKMPYTL QTIDNLFQSL 250 260 270 280 290 300 ALGNHDLMNV GRSLLFRPFR SGDLDLIRLD DSGAKLKVPI NNSIVLRLTC KDPIQWQEYW 310 320 330 340 350 360 KHVIRKLFDS TATKEYKRSG SKISQQVYVR SNNPDYTSPK RNDDMPISSV KISDTIHNGR 370 380 390 400 410 420 TLHRSIPLPG SLSSLIETSN EYPDEESLSI MSERATVSED SDLDTSLKDI ESLSCEKLIE 430 440 450 460 470 480 LDKSIQVPLS PKYMDTPTLK NIRTASQTFS LESVSPELIE SVASEIDDSE SIISEDGKDK 490 500 510 520 530 540 RDKDLFDPDI DFYKPTLYRR KSSSLLSIFS KNKKNLTIDI PKNHSRSLFS LPGNQQSVTP 550 560 570 580 590 600 VSATPHDDNV DETYVSFPLS INTSGGAVYF ENDSVKVSLW NGKSWVPLSK DMLCLSLILS 610 620 630 640 650 660 GDNETLLIVY KDFEKEKCKL VVKLEPTWKY NRSTAQDVQL RIPSSDFKAS VFGTLHDLTL 670 680 690 700 710 720 SIRCAQAAKL VNVLQYQLQS SQTSSLSPST TTGTLSTVSS SSCFSRNVTR SSTENSELAN 730 740 MKDSSEYISS SLLLSSVKVR QLRNM

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The sequence of 24.3 kb from chromosome X reveals five complete open reading frames, all of which correspond to new genes, and a tandem insertion of a Ty1 transposon." Zagulski M., Babinska B., Gromadka R., Migdalski A., Rytka J., Sulicka J., Herbert C.J. Yeast 11:1179-1186(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c and VP102-10A.
[2]	"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X." Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K. , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L. EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679.
[3]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X87297 Genomic DNA. Translation: CAA60723.1. X87298 Genomic DNA. Translation: CAA60727.1. Sequence problems. Z49530 Genomic DNA. Translation: CAA89557.1. BK006943 Genomic DNA. Translation: DAA08819.1.
PIR	S57048.
RefSeq	NP_012564.3. NM_001181688.3.
3D structure databases
ProteinModelPortal	P47101.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-5695N.
MINT	MINT-480071.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YJR030C; YJR030C; YJR030C.
GeneID	853487.
KEGG	sce:YJR030C. sce:YJR033C.
Organism-specific databases
CYGD	YJR030c.
SGD	S000003791. YJR030C.
Phylogenomic databases
eggNOG	NOG47681.
GeneTree	ENSGT00530000069267.
OMA	ESPREAN.
OrthoDB	EOG4CZFR7.
Gene expression databases
Genevestigator	P47101.
GermOnline	YJR030C. Saccharomyces cerevisiae.
Family and domain databases
ProtoNet	Search...
Other
NextBio	974110.

Entry information

Entry name

YJ00_YEAST

Accession

Primary (citable) accession number: P47101
Secondary accession number(s): D6VWK3, P87321, Q05848

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1996
Last sequence update:	November 2, 2010
Last modified:	April 3, 2013
This is version 66 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program