ID   YJY2_YEAST              Reviewed;         132 AA.
AC   P47087; D6VWI8;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   25-MAY-2022, sequence version 2.
DT   24-JAN-2024, entry version 132.
DE   RecName: Full=Uncharacterized protein YJR012C {ECO:0000305};
GN   OrderedLocusNames=YJR012C {ECO:0000312|SGD:S000003773};
GN   ORFNames=J1440, YJR83.25;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=8641269; DOI=10.1002/j.1460-2075.1996.tb00557.x;
RA   Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C.,
RA   Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D.,
RA   Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J.,
RA   Heumann K., Hilger F., Hollenberg C.P., Huang M.-E., Jacq C.,
RA   Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E.,
RA   Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T.,
RA   Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B.,
RA   Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R.,
RA   Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N.,
RA   To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H.,
RA   von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.;
RT   "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X.";
RL   EMBO J. 15:2031-2049(1996).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=17322287; DOI=10.1101/gr.6037607;
RA   Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA   Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA   Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA   Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA   LaBaer J.;
RT   "Approaching a complete repository of sequence-verified protein-encoding
RT   clones for Saccharomyces cerevisiae.";
RL   Genome Res. 17:536-543(2007).
RN   [4]
RP   IDENTIFICATION BY MASS SPECTROMETRY.
RX   PubMed=14690591; DOI=10.1016/s1097-2765(03)00476-3;
RA   Hazbun T.R., Malmstroem L., Anderson S., Graczyk B.J., Fox B., Riffle M.,
RA   Sundin B.A., Aranda J.D., McDonald W.H., Chiu C.-H., Snydsman B.E.,
RA   Bradley P., Muller E.G.D., Fields S., Baker D., Yates J.R. III, Davis T.N.;
RT   "Assigning function to yeast proteins by integration of technologies.";
RL   Mol. Cell 12:1353-1365(2003).
RN   [5]
RP   LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX   PubMed=14562106; DOI=10.1038/nature02046;
RA   Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA   O'Shea E.K., Weissman J.S.;
RT   "Global analysis of protein expression in yeast.";
RL   Nature 425:737-741(2003).
RN   [6]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-101, AND IDENTIFICATION BY
RP   MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=19779198; DOI=10.1126/science.1172867;
RA   Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.;
RT   "Global analysis of Cdk1 substrate phosphorylation sites provides insights
RT   into evolution.";
RL   Science 325:1682-1686(2009).
RN   [7]
RP   IDENTIFICATION OF PROBABLE INITIATOR METHIONINE.
RX   PubMed=29632376; DOI=10.1038/s41588-018-0087-y;
RA   Sadhu M.J., Bloom J.S., Day L., Siegel J.J., Kosuri S., Kruglyak L.;
RT   "Highly parallel genome variant engineering with CRISPR-Cas9.";
RL   Nat. Genet. 50:510-514(2018).
CC   -!- SUBUNIT: Copurifies with proteins HOL1, MMP1, PEX7 and PLB1.
CC       {ECO:0000269|PubMed:14690591}.
CC   -!- MISCELLANEOUS: Present with 538 molecules/cell in log phase SD medium.
CC       {ECO:0000269|PubMed:14562106}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAS56226.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC       Sequence=CAA60934.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC       Sequence=CAA89536.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; X87611; CAA60934.1; ALT_INIT; Genomic_DNA.
DR   EMBL; Z49512; CAA89536.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AY557900; AAS56226.1; ALT_INIT; Genomic_DNA.
DR   EMBL; BK006943; DAA08804.2; -; Genomic_DNA.
DR   PIR; S55200; S55200.
DR   RefSeq; NP_012546.3; NM_001181670.3.
DR   AlphaFoldDB; P47087; -.
DR   BioGRID; 300661; 9.
DR   DIP; DIP-5042N; -.
DR   IntAct; P47087; 5.
DR   MINT; P47087; -.
DR   STRING; 4932.YJR012C; -.
DR   iPTMnet; P47087; -.
DR   PaxDb; 4932-YJR012C; -.
DR   PeptideAtlas; P47087; -.
DR   EnsemblFungi; YJR012C_mRNA; YJR012C; YJR012C.
DR   GeneID; 853469; -.
DR   KEGG; sce:YJR012C; -.
DR   AGR; SGD:S000003773; -.
DR   SGD; S000003773; YJR012C.
DR   VEuPathDB; FungiDB:YJR012C; -.
DR   eggNOG; ENOG502SBU0; Eukaryota.
DR   HOGENOM; CLU_1327052_0_0_1; -.
DR   InParanoid; P47087; -.
DR   BioCyc; YEAST:G3O-31657-MONOMER; -.
DR   BioGRID-ORCS; 853469; 1 hit in 10 CRISPR screens.
DR   PRO; PR:P47087; -.
DR   Proteomes; UP000002311; Chromosome X.
DR   RNAct; P47087; Protein.
DR   Pfam; PF17733; DUF5572; 1.
PE   1: Evidence at protein level;
KW   Phosphoprotein; Reference proteome.
FT   CHAIN           1..132
FT                   /note="Uncharacterized protein YJR012C"
FT                   /id="PRO_0000203083"
FT   REGION          36..69
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          97..132
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        53..69
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         101
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:19779198"
SQ   SEQUENCE   132 AA;  14566 MW;  49A2BA49B2F25AC4 CRC64;
     MAAGGELSYE ELLDHILNNK PIPNIVEVPN VTLDEGLAST PSLRPRPRPW EGQLQHQSHQ
     GSLDKPNISL DIDQESLEGM TSLTRLSECY DIQSKLQIND SDNDNDDNNN DNNKGDGNDD
     DNNTVTANPT AR
//