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P47081

- COX16_YEAST

UniProt

P47081 - COX16_YEAST

Protein

Cytochrome c oxidase assembly protein COX16, mitochondrial

Gene

COX16

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 91 (01 Oct 2014)
      Sequence version 1 (01 Feb 1996)
      Previous versions | rss
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    Functioni

    Required for the assembly of cytochrome c oxidase.1 Publication

    GO - Biological processi

    1. mitochondrial respiratory chain complex IV assembly Source: SGD

    Enzyme and pathway databases

    BioCyciYEAST:G3O-31482-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cytochrome c oxidase assembly protein COX16, mitochondrial
    Gene namesi
    Name:COX16
    Ordered Locus Names:YJL003W
    ORF Names:J1403, YJR83.2
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome X

    Organism-specific databases

    CYGDiYJL003w.
    SGDiS000003540. COX16.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. mitochondrial inner membrane Source: SGD

    Keywords - Cellular componenti

    Membrane, Mitochondrion, Mitochondrion inner membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini? – 118Cytochrome c oxidase assembly protein COX16, mitochondrialPRO_0000203080
    Transit peptidei1 – ?MitochondrionSequence Analysis

    Proteomic databases

    MaxQBiP47081.
    PaxDbiP47081.

    Expressioni

    Gene expression databases

    GenevestigatoriP47081.

    Interactioni

    Protein-protein interaction databases

    BioGridi33754. 4 interactions.
    STRINGi4932.YJL003W.

    Structurei

    3D structure databases

    ProteinModelPortaliP47081.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei33 – 5321HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the COX16 family.Curated

    Keywords - Domaini

    Transit peptide, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG80748.
    HOGENOMiHOG000217274.
    KOiK18182.
    OMAiATAIRYE.
    OrthoDBiEOG7N0CHX.

    Family and domain databases

    InterProiIPR020164. Cyt_c_Oxase_assmbl_COX16.
    [Graphical view]
    PfamiPF14138. COX16. 1 hit.
    [Graphical view]
    ProDomiPD076120. Cyt_c_Oxase_assmbl_COX16. 1 hit.
    [Graphical view] [Entries sharing at least one domain]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P47081-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSFSGKKFRS RRQQLVYEAS LAGRYKKALS KHPFLFFGLP FCATIVLGSF    50
    WLSSFTAIKY EQGDRKVQEI NEEDILKIRK NQREFDIKEE YYRLQGLSEE 100
    DWEPVRVARL KDESENVW 118
    Length:118
    Mass (Da):14,077
    Last modified:February 1, 1996 - v1
    Checksum:i4A45F140B802DCC9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X87611 Genomic DNA. Translation: CAA60919.1.
    Z49278 Genomic DNA. Translation: CAA89293.1.
    AY558241 Genomic DNA. Translation: AAS56567.1.
    BK006943 Genomic DNA. Translation: DAA08788.1.
    PIRiS55185.
    RefSeqiNP_012531.1. NM_001181437.1.

    Genome annotation databases

    EnsemblFungiiYJL003W; YJL003W; YJL003W.
    GeneIDi853454.
    KEGGisce:YJL003W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X87611 Genomic DNA. Translation: CAA60919.1 .
    Z49278 Genomic DNA. Translation: CAA89293.1 .
    AY558241 Genomic DNA. Translation: AAS56567.1 .
    BK006943 Genomic DNA. Translation: DAA08788.1 .
    PIRi S55185.
    RefSeqi NP_012531.1. NM_001181437.1.

    3D structure databases

    ProteinModelPortali P47081.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 33754. 4 interactions.
    STRINGi 4932.YJL003W.

    Proteomic databases

    MaxQBi P47081.
    PaxDbi P47081.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YJL003W ; YJL003W ; YJL003W .
    GeneIDi 853454.
    KEGGi sce:YJL003W.

    Organism-specific databases

    CYGDi YJL003w.
    SGDi S000003540. COX16.

    Phylogenomic databases

    eggNOGi NOG80748.
    HOGENOMi HOG000217274.
    KOi K18182.
    OMAi ATAIRYE.
    OrthoDBi EOG7N0CHX.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-31482-MONOMER.

    Miscellaneous databases

    NextBioi 974020.

    Gene expression databases

    Genevestigatori P47081.

    Family and domain databases

    InterProi IPR020164. Cyt_c_Oxase_assmbl_COX16.
    [Graphical view ]
    Pfami PF14138. COX16. 1 hit.
    [Graphical view ]
    ProDomi PD076120. Cyt_c_Oxase_assmbl_COX16. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."
      Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K.
      , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.
      EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    4. "COX16 encodes a novel protein required for the assembly of cytochrome oxidase in Saccharomyces cerevisiae."
      Carlson C.G., Barrientos A., Tzagoloff A., Glerum D.M.
      J. Biol. Chem. 278:3770-3775(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, SUBCELLULAR LOCATION.
    5. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
    6. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
      Strain: ATCC 76625 / YPH499.
    7. "Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics."
      Reinders J., Zahedi R.P., Pfanner N., Meisinger C., Sickmann A.
      J. Proteome Res. 5:1543-1554(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiCOX16_YEAST
    AccessioniPrimary (citable) accession number: P47081
    Secondary accession number(s): D6VWH2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1996
    Last sequence update: February 1, 1996
    Last modified: October 1, 2014
    This is version 91 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Present with 672 molecules/cell in log phase SD medium.1 Publication

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    3. Yeast chromosome X
      Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

    External Data

    Dasty 3