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P47081

- COX16_YEAST

UniProt

P47081 - COX16_YEAST

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Protein
Cytochrome c oxidase assembly protein COX16, mitochondrial
Gene
COX16, YJL003W, J1403, YJR83.2
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Required for the assembly of cytochrome c oxidase.1 Publication

GO - Biological processi

  1. mitochondrial respiratory chain complex IV assembly Source: SGD
Complete GO annotation...

Enzyme and pathway databases

BioCyciYEAST:G3O-31482-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase assembly protein COX16, mitochondrial
Gene namesi
Name:COX16
Ordered Locus Names:YJL003W
ORF Names:J1403, YJR83.2
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome X

Organism-specific databases

CYGDiYJL003w.
SGDiS000003540. COX16.

Subcellular locationi

Mitochondrion inner membrane; Single-pass membrane protein Reviewed prediction 3 Publications

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei33 – 5321Helical; Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. mitochondrial inner membrane Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini? – 118Cytochrome c oxidase assembly protein COX16, mitochondrialPRO_0000203080
Transit peptidei1 – ?Mitochondrion Reviewed prediction

Proteomic databases

MaxQBiP47081.
PaxDbiP47081.

Expressioni

Gene expression databases

GenevestigatoriP47081.

Interactioni

Protein-protein interaction databases

BioGridi33754. 4 interactions.
STRINGi4932.YJL003W.

Structurei

3D structure databases

ProteinModelPortaliP47081.

Family & Domainsi

Sequence similaritiesi

Belongs to the COX16 family.

Keywords - Domaini

Transit peptide, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG80748.
HOGENOMiHOG000217274.
KOiK18182.
OMAiATAIRYE.
OrthoDBiEOG7N0CHX.

Family and domain databases

InterProiIPR020164. Cyt_c_Oxase_assmbl_COX16.
[Graphical view]
PfamiPF14138. COX16. 1 hit.
[Graphical view]
ProDomiPD076120. Cyt_c_Oxase_assmbl_COX16. 1 hit.
[Graphical view] [Entries sharing at least one domain]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P47081-1 [UniParc]FASTAAdd to Basket

« Hide

MSFSGKKFRS RRQQLVYEAS LAGRYKKALS KHPFLFFGLP FCATIVLGSF    50
WLSSFTAIKY EQGDRKVQEI NEEDILKIRK NQREFDIKEE YYRLQGLSEE 100
DWEPVRVARL KDESENVW 118
Length:118
Mass (Da):14,077
Last modified:February 1, 1996 - v1
Checksum:i4A45F140B802DCC9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X87611 Genomic DNA. Translation: CAA60919.1.
Z49278 Genomic DNA. Translation: CAA89293.1.
AY558241 Genomic DNA. Translation: AAS56567.1.
BK006943 Genomic DNA. Translation: DAA08788.1.
PIRiS55185.
RefSeqiNP_012531.1. NM_001181437.1.

Genome annotation databases

EnsemblFungiiYJL003W; YJL003W; YJL003W.
GeneIDi853454.
KEGGisce:YJL003W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X87611 Genomic DNA. Translation: CAA60919.1 .
Z49278 Genomic DNA. Translation: CAA89293.1 .
AY558241 Genomic DNA. Translation: AAS56567.1 .
BK006943 Genomic DNA. Translation: DAA08788.1 .
PIRi S55185.
RefSeqi NP_012531.1. NM_001181437.1.

3D structure databases

ProteinModelPortali P47081.
ModBasei Search...

Protein-protein interaction databases

BioGridi 33754. 4 interactions.
STRINGi 4932.YJL003W.

Proteomic databases

MaxQBi P47081.
PaxDbi P47081.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YJL003W ; YJL003W ; YJL003W .
GeneIDi 853454.
KEGGi sce:YJL003W.

Organism-specific databases

CYGDi YJL003w.
SGDi S000003540. COX16.

Phylogenomic databases

eggNOGi NOG80748.
HOGENOMi HOG000217274.
KOi K18182.
OMAi ATAIRYE.
OrthoDBi EOG7N0CHX.

Enzyme and pathway databases

BioCyci YEAST:G3O-31482-MONOMER.

Miscellaneous databases

NextBioi 974020.

Gene expression databases

Genevestigatori P47081.

Family and domain databases

InterProi IPR020164. Cyt_c_Oxase_assmbl_COX16.
[Graphical view ]
Pfami PF14138. COX16. 1 hit.
[Graphical view ]
ProDomi PD076120. Cyt_c_Oxase_assmbl_COX16. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."
    Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K.
    , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.
    EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. "COX16 encodes a novel protein required for the assembly of cytochrome oxidase in Saccharomyces cerevisiae."
    Carlson C.G., Barrientos A., Tzagoloff A., Glerum D.M.
    J. Biol. Chem. 278:3770-3775(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION.
  5. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  6. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    Strain: ATCC 76625 / YPH499.
  7. "Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics."
    Reinders J., Zahedi R.P., Pfanner N., Meisinger C., Sickmann A.
    J. Proteome Res. 5:1543-1554(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiCOX16_YEAST
AccessioniPrimary (citable) accession number: P47081
Secondary accession number(s): D6VWH2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: June 11, 2014
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 672 molecules/cell in log phase SD medium.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome X
    Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

External Data

Dasty 3

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