Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P47056

- IRC18_YEAST

UniProt

P47056 - IRC18_YEAST

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Outer spore wall protein 6

Gene

IRC18

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Involved in spore wall assembly.1 Publication

GO - Biological processi

  1. ascospore wall assembly Source: SGD
Complete GO annotation...

Keywords - Biological processi

Sporulation

Enzyme and pathway databases

BioCyciYEAST:G3O-31503-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Outer spore wall protein 61 Publication
Alternative name(s):
Increased recombination centers protein 181 Publication
Gene namesi
Name:IRC181 Publication
Synonyms:OSW61 Publication
Ordered Locus Names:YJL037WImported
ORF Names:J1234
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome X

Organism-specific databases

CYGDiYJL037w.
SGDiS000003574. IRC18.

Subcellular locationi

Membrane Sequence Analysis; Multi-pass membrane protein Sequence Analysis

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini27 – 174148ExtracellularBy similarityAdd
BLAST
Transmembranei175 – 19521HelicalSequence AnalysisAdd
BLAST
Topological domaini196 – 1994CytoplasmicBy similarity
Transmembranei200 – 22021HelicalSequence AnalysisAdd
BLAST
Topological domaini221 – 2244ExtracellularBy similarity

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Disruption phenotypei

Displays increased levels of spontaneous RAD52 foci in proliferating diploid cells (PubMed:18085829). A combined deletion of the LOH1/OSW4 and IRC18/OSW6 has reduced dityrosine incorporation in the outer spore wall (PubMed:23966878).2 Publications

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2626Sequence AnalysisAdd
BLAST
Chaini27 – 224198Outer spore wall protein 6PRO_0000203069Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi74 – 741N-linked (GlcNAc...)PROSITE-ProRule annotation
Glycosylationi104 – 1041N-linked (GlcNAc...)PROSITE-ProRule annotation

Keywords - PTMi

Glycoprotein

Expressioni

Inductioni

In respiratory-deficient cells and by heat.2 Publications

Gene expression databases

GenevestigatoriP47056.

Interactioni

Protein-protein interaction databases

BioGridi33722. 5 interactions.
STRINGi4932.YJL037W.

Structurei

3D structure databases

ProteinModelPortaliP47056.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the OSW4/6 family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00530000068883.
InParanoidiP47056.
OMAiNTFETET.
OrthoDBiEOG7CVQ8V.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P47056-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKVQMIERIF LIQLCLLTVV LASSRAVVEF ESTGTKLVNS LRVLAAYSQS
60 70 80 90 100
SVCVDEKISG IERQIEEVKD MYGNHSFILK GLNGILNNKV NMLTREIQME
110 120 130 140 150
TVGNNTFETE TGKLTKGLNR AVNISPFKYI KKFKTVSTKK FESLLNKYDL
160 170 180 190 200
VAKKGGELTE EQKKKKEVLS RISRVVAATT IEAGLAQGVV DLCITVTTSL
210 220
CLVSASIGGV GFLIWLTIIY QALT
Length:224
Mass (Da):24,746
Last modified:February 1, 1996 - v1
Checksum:i6C17841176EADC1F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49312 Genomic DNA. Translation: CAA89328.1.
AY558244 Genomic DNA. Translation: AAS56570.1.
BK006943 Genomic DNA. Translation: DAA08762.1.
PIRiS56809.
RefSeqiNP_012497.3. NM_001181471.3.

Genome annotation databases

EnsemblFungiiYJL037W; YJL037W; YJL037W.
GeneIDi853414.
KEGGisce:YJL037W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49312 Genomic DNA. Translation: CAA89328.1 .
AY558244 Genomic DNA. Translation: AAS56570.1 .
BK006943 Genomic DNA. Translation: DAA08762.1 .
PIRi S56809.
RefSeqi NP_012497.3. NM_001181471.3.

3D structure databases

ProteinModelPortali P47056.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 33722. 5 interactions.
STRINGi 4932.YJL037W.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YJL037W ; YJL037W ; YJL037W .
GeneIDi 853414.
KEGGi sce:YJL037W.

Organism-specific databases

CYGDi YJL037w.
SGDi S000003574. IRC18.

Phylogenomic databases

GeneTreei ENSGT00530000068883.
InParanoidi P47056.
OMAi NTFETET.
OrthoDBi EOG7CVQ8V.

Enzyme and pathway databases

BioCyci YEAST:G3O-31503-MONOMER.

Miscellaneous databases

NextBioi 973928.

Gene expression databases

Genevestigatori P47056.

Family and domain databases

ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."
    Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K.
    , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.
    EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. Cited for: INDUCTION.
  5. "Response of genes associated with mitochondrial function to mild heat stress in yeast Saccharomyces cerevisiae."
    Sakaki K., Tashiro K., Kuhara S., Mihara K.
    J. Biochem. 134:373-384(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: INDUCTION.
  6. "Genome-wide analysis of Rad52 foci reveals diverse mechanisms impacting recombination."
    Alvaro D., Lisby M., Rothstein R.
    PLoS Genet. 3:E228-E228(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: DISRUPTION PHENOTYPE.
  7. "A highly redundant gene network controls assembly of the outer spore wall in S. cerevisiae."
    Lin C.P., Kim C., Smith S.O., Neiman A.M.
    PLoS Genet. 9:E1003700-E1003700(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, DISRUPTION PHENOTYPE.

Entry informationi

Entry nameiIRC18_YEAST
AccessioniPrimary (citable) accession number: P47056
Secondary accession number(s): D6VWE6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: October 29, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome X
    Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

External Data

Dasty 3