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P47043 (ZAP1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 119. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Zinc-responsive transcriptional regulator ZAP1
Gene names
Name:ZAP1
Ordered Locus Names:YJL056C
ORF Names:J1145
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length880 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Involved in zinc ion homeostasis by zinc-responsive transcriptional regulation.

Subcellular location

Nucleus Potential.

Sequence similarities

Contains 7 C2H2-type zinc fingers.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 880880Zinc-responsive transcriptional regulator ZAP1
PRO_0000046859

Regions

Zinc finger579 – 60426C2H2-type 1
Zinc finger616 – 64126C2H2-type 2; atypical
Zinc finger705 – 73026C2H2-type 3
Zinc finger738 – 76225C2H2-type 4
Zinc finger768 – 79023C2H2-type 5
Zinc finger796 – 81823C2H2-type 6
Zinc finger824 – 84623C2H2-type 7

Amino acid modifications

Modified residue1561Phosphoserine Ref.3
Modified residue1661Phosphoserine Ref.3
Modified residue5151Phosphoserine Ref.3

Secondary structure

...... 880
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P47043 [UniParc].

Last modified February 1, 1996. Version 1.
Checksum: 4B0C2E818FAFE7F6

FASTA88098,866
        10         20         30         40         50         60 
MDALTPRDSP KRDDSMATSA ATAASAKPDA LTIGKEGIVH GHIHNYNNLT YIHGHLHHSA 

        70         80         90        100        110        120 
PVNDSSASAT PAAAAVADAA TSAFASGASH DMGGDCHVNE KCKEYTDCQH FEFLNYHNNP 

       130        140        150        160        170        180 
SLTKYNDTAT YNSNNHSFAN NFHSVASDPT SPQQNSKSDL PRRKDSWFND DLILLPSSKK 

       190        200        210        220        230        240 
NKPNPPPGSD DCYCTPKILE ICCDETHPKS EANIKQGESD QPTKKDISEN GNDVAIFTDV 

       250        260        270        280        290        300 
KNDHLMPNFN LHDQYCNSTN HDSHNHNNTV PDSFSQLMSH LSEIDCDLTC DTPCTASTSA 

       310        320        330        340        350        360 
TSGHKFVQDH QSSNNDDVFH KYCKFCEEST DNQPCSKHMH LESKPPQLPP KCSSLRKPTN 

       370        380        390        400        410        420 
TLQGTNHAYH EHILNTDMDL KILEDLCNIS SLYEVPFGKH INHHDHNNAG NGCDGSSTGN 

       430        440        450        460        470        480 
NENGNQTMNL LLSSINRCNP KNNLNGSNNN TAGATSTDHQ HHHHRIQFHS HKPNRNNIVN 

       490        500        510        520        530        540 
NSGISAANTT ADLTNNDLND LISREYSYER FRNQSEPPSL PKVTHQNQKN RRSWPTKDLE 

       550        560        570        580        590        600 
STDFSSLEDS LPSSISPPIQ TTSTINFNWC FKEEKNNDLK CKWKECPESC SSLFDLQRHL 

       610        620        630        640        650        660 
LKDHVSQDFK HPMEPLACNW EDCDFLGDDT CSIVNHINCQ HGINFDIQFA NPDSFLPGSI 

       670        680        690        700        710        720 
SKEKHHLLHC PNPQTHEVSK ADGAPDMTSA NDVSNIPPIK QPEQVICQWD GCNKSFSSAQ 

       730        740        750        760        770        780 
ELNDHLEAVH LTRGKSEYQC LWHDCHRTFP QRQKLIRHLK VHSKYKPYKC KTCKRCFSSE 

       790        800        810        820        830        840 
ETLVQHTRTH SGEKPYKCHI CNKKFAISSS LKIHIRTHTG EKPLQCKICG KRFNESSNLS 

       850        860        870        880 
KHIKTHQKKY KCSDCSKSFD DLGKLNSQKV KCALERKPYL 

« Hide

References

« Hide 'large scale' references
[1]"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."
Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K. expand/collapse author list , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.
EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-156; SER-166 AND SER-515, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z49331 Genomic DNA. Translation: CAA89347.1.
BK006943 Genomic DNA. Translation: DAA08742.1.
PIRS56828.
RefSeqNP_012479.1. NM_001181489.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1ZW8NMR-A578-641[»]
ProteinModelPortalP47043.
SMRP47043. Positions 577-879.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid33698. 72 interactions.
DIPDIP-1565N.
IntActP47043. 5 interactions.
MINTMINT-386852.
STRING4932.YJL056C.

Proteomic databases

PaxDbP47043.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYJL056C; YJL056C; YJL056C.
GeneID853390.
KEGGsce:YJL056C.

Organism-specific databases

CYGDYJL056c.
SGDS000003592. ZAP1.

Phylogenomic databases

eggNOGCOG5048.
GeneTreeENSGT00750000117476.
HOGENOMHOG000141792.
OMAGHIHNYN.
OrthoDBEOG708W7K.

Enzyme and pathway databases

BioCycYEAST:G3O-31519-MONOMER.

Gene expression databases

GenevestigatorP47043.

Family and domain databases

Gene3D3.30.160.60. 5 hits.
InterProIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamPF00096. zf-C2H2. 1 hit.
[Graphical view]
SMARTSM00355. ZnF_C2H2. 7 hits.
[Graphical view]
PROSITEPS00028. ZINC_FINGER_C2H2_1. 6 hits.
PS50157. ZINC_FINGER_C2H2_2. 5 hits.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceP47043.
NextBio973861.

Entry information

Entry nameZAP1_YEAST
AccessionPrimary (citable) accession number: P47043
Secondary accession number(s): D6VWC6
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: April 16, 2014
This is version 119 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome X

Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references