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P47034

- ICS3_YEAST

UniProt

P47034 - ICS3_YEAST

Protein

Increased copper sensitivity protein 3

Gene

ICS3

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 74 (01 Oct 2014)
      Sequence version 1 (01 Feb 1996)
      Previous versions | rss
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    Functioni

    Enzyme and pathway databases

    BioCyciYEAST:G3O-31534-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Increased copper sensitivity protein 3
    Gene namesi
    Name:ICS3
    Ordered Locus Names:YJL077C
    ORF Names:J1033
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome X

    Organism-specific databases

    CYGDiYJL077c.
    SGDiS000003613. ICS3.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    Pathology & Biotechi

    Disruption phenotypei

    Increases sensitivity to copper.1 Publication

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 131131Increased copper sensitivity protein 3PRO_0000203052Add
    BLAST

    Expressioni

    Gene expression databases

    GenevestigatoriP47034.

    Interactioni

    Protein-protein interaction databases

    BioGridi33679. 5 interactions.
    MINTiMINT-4806718.
    STRINGi4932.YJL077C.

    Structurei

    3D structure databases

    ProteinModelPortaliP47034.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei35 – 5521HelicalSequence AnalysisAdd
    BLAST
    Transmembranei74 – 9421HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    OMAiISKNCIA.
    OrthoDBiEOG7V4BB9.

    Sequencei

    Sequence statusi: Complete.

    P47034-1 [UniParc]FASTAAdd to Basket

    « Hide

    MHISLPTRNK SYFRIRTRTY QIGLYHSDSS PIRDISVLHL LIATLCTIFF    50
    PIFFSLSKVQ VVQWQGTTIS KNCIALTMSF PLNAIPGMYL IIAFPRLQTV 100
    IPLQRNTPVR ITKSVIVKGA VSVPRISSPM H 131
    Length:131
    Mass (Da):14,828
    Last modified:February 1, 1996 - v1
    Checksum:i1A5AB2ABC6C8BB97
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z49352 Genomic DNA. Translation: CAA89369.1.
    AY692701 Genomic DNA. Translation: AAT92720.1.
    BK006943 Genomic DNA. Translation: DAA08723.1.
    PIRiS56853.
    RefSeqiNP_012458.1. NM_001181510.1.

    Genome annotation databases

    EnsemblFungiiYJL077C; YJL077C; YJL077C.
    GeneIDi853368.
    KEGGisce:YJL077C.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z49352 Genomic DNA. Translation: CAA89369.1 .
    AY692701 Genomic DNA. Translation: AAT92720.1 .
    BK006943 Genomic DNA. Translation: DAA08723.1 .
    PIRi S56853.
    RefSeqi NP_012458.1. NM_001181510.1.

    3D structure databases

    ProteinModelPortali P47034.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 33679. 5 interactions.
    MINTi MINT-4806718.
    STRINGi 4932.YJL077C.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YJL077C ; YJL077C ; YJL077C .
    GeneIDi 853368.
    KEGGi sce:YJL077C.

    Organism-specific databases

    CYGDi YJL077c.
    SGDi S000003613. ICS3.

    Phylogenomic databases

    OMAi ISKNCIA.
    OrthoDBi EOG7V4BB9.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-31534-MONOMER.

    Miscellaneous databases

    NextBioi 973804.

    Gene expression databases

    Genevestigatori P47034.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."
      Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K.
      , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.
      EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    4. Cited for: DISRUPTION PHENOTYPE.

    Entry informationi

    Entry nameiICS3_YEAST
    AccessioniPrimary (citable) accession number: P47034
    Secondary accession number(s): D6VWA7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1996
    Last sequence update: February 1, 1996
    Last modified: October 1, 2014
    This is version 74 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    2. Yeast chromosome X
      Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

    External Data

    Dasty 3