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Protein

Increased copper sensitivity protein 3

Gene

ICS3

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Biological processi

  • copper ion homeostasis Source: SGD
Complete GO annotation...

Enzyme and pathway databases

BioCyciYEAST:G3O-31534-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Increased copper sensitivity protein 3
Gene namesi
Name:ICS3
Ordered Locus Names:YJL077C
ORF Names:J1033
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome X

Organism-specific databases

EuPathDBiFungiDB:YJL077C.
SGDiS000003613. ICS3.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei35 – 5521HelicalSequence analysisAdd
BLAST
Transmembranei74 – 9421HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Disruption phenotypei

Increases sensitivity to copper.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 131131Increased copper sensitivity protein 3PRO_0000203052Add
BLAST

Interactioni

Protein-protein interaction databases

BioGridi33679. 5 interactions.
MINTiMINT-4806718.

Structurei

3D structure databases

ProteinModelPortaliP47034.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

OrthoDBiEOG092C5CUQ.

Sequencei

Sequence statusi: Complete.

P47034-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHISLPTRNK SYFRIRTRTY QIGLYHSDSS PIRDISVLHL LIATLCTIFF
60 70 80 90 100
PIFFSLSKVQ VVQWQGTTIS KNCIALTMSF PLNAIPGMYL IIAFPRLQTV
110 120 130
IPLQRNTPVR ITKSVIVKGA VSVPRISSPM H
Length:131
Mass (Da):14,828
Last modified:February 1, 1996 - v1
Checksum:i1A5AB2ABC6C8BB97
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49352 Genomic DNA. Translation: CAA89369.1.
AY692701 Genomic DNA. Translation: AAT92720.1.
BK006943 Genomic DNA. Translation: DAA08723.1.
PIRiS56853.
RefSeqiNP_012458.1. NM_001181510.1.

Genome annotation databases

EnsemblFungiiYJL077C; YJL077C; YJL077C.
GeneIDi853368.
KEGGisce:YJL077C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49352 Genomic DNA. Translation: CAA89369.1.
AY692701 Genomic DNA. Translation: AAT92720.1.
BK006943 Genomic DNA. Translation: DAA08723.1.
PIRiS56853.
RefSeqiNP_012458.1. NM_001181510.1.

3D structure databases

ProteinModelPortaliP47034.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi33679. 5 interactions.
MINTiMINT-4806718.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYJL077C; YJL077C; YJL077C.
GeneIDi853368.
KEGGisce:YJL077C.

Organism-specific databases

EuPathDBiFungiDB:YJL077C.
SGDiS000003613. ICS3.

Phylogenomic databases

OrthoDBiEOG092C5CUQ.

Enzyme and pathway databases

BioCyciYEAST:G3O-31534-MONOMER.

Miscellaneous databases

PROiP47034.

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiICS3_YEAST
AccessioniPrimary (citable) accession number: P47034
Secondary accession number(s): D6VWA7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: September 7, 2016
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome X
    Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.