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Protein

Transposon Ty4-J Gag polyprotein

Gene

TY4A-J

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome.By similarity

GO - Molecular functioni

  1. RNA binding Source: SGD
  2. zinc ion binding Source: InterPro

GO - Biological processi

  1. transposition, RNA-mediated Source: SGD
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Transposon Ty4-J Gag polyprotein
Short name:
TY4A
Short name:
Transposon Ty4 protein A
Gene namesi
Name:TY4A-J
Synonyms:YJLWTy4-1 GAG
Ordered Locus Names:YJL114W
ORF Names:J0775
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311 Componenti: Chromosome X

Organism-specific databases

CYGDiYJL114w.
SGDiS000003650. YJL114W.

Subcellular locationi

GO - Cellular componenti

  1. retrotransposon nucleocapsid Source: SGD
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 414414Transposon Ty4-J Gag polyproteinPRO_0000203501Add
BLAST

Expressioni

Gene expression databases

GenevestigatoriP47023.

Interactioni

Protein-protein interaction databases

BioGridi33641. 6 interactions.
DIPiDIP-7219N.
IntActiP47023. 7 interactions.
MINTiMINT-390812.
STRINGi4932.YJL114W.

Structurei

3D structure databases

ProteinModelPortaliP47023.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili39 – 11577Sequence AnalysisAdd
BLAST

Keywords - Domaini

Coiled coil

Phylogenomic databases

HOGENOMiHOG000155564.
InParanoidiP47023.
OrthoDBiEOG7G1VGM.

Family and domain databases

InterProiIPR001878. Znf_CCHC.
[Graphical view]
SMARTiSM00343. ZnF_C2HC. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by ribosomal frameshifting. AlignAdd to basket

Note: The Gag-Pol polyprotein is generated by a +1 ribosomal frameshift.

Isoform Transposon Ty4-J Gag polyprotein (identifier: P47023-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MATPVRGETR NVIDDNISAR IQSKVKTNDT VRQTPSSLRK VSIKDEQVRQ
60 70 80 90 100
YQRNLNRFKT ILNGLKAEEE KLSEADDIQM LAEKLLKLGE TIDKVENRIV
110 120 130 140 150
DLVEKIQLLE TNENNNILHE HIDATGTYYL FDTLTSTNKR FYPKDCVFDY
160 170 180 190 200
RTNNVENIPI LLNNFKKFIK KYQFDDVFEN DIIEIDPREN EILCKIIKEG
210 220 230 240 250
LGESLDIMNT NTTDIFRIID GLKKQNIEVC MVEMSELEPG EKVLVDTTCR
260 270 280 290 300
NSALLMNKLQ KLVLMEKWIF SKCCQDCPNL KDYLQEAIMG TLHESLRNSV
310 320 330 340 350
KQRLYNIPHD VGIDHEEFLI NTVIETVIDL SPIADDQIEN SCMYCKSVFH
360 370 380 390 400
CSINCKKKPN RELRPDSTNF SKTYYLQGAQ RQQPLKSSAK RTKVLEQDTK
410
KVEQSVQQQK TGNY

Note: Produced by conventional translation.

Length:414
Mass (Da):48,035
Last modified:February 1, 1996 - v1
Checksum:i541F3767BE5F8275
GO
Isoform Transposon Ty4-J Gag-Pol polyprotein (identifier: P47024-1) [UniParc]FASTAAdd to basket

The sequence of this isoform can be found in the external entry P47024.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.

Note: Produced by +1 ribosomal frameshifting between codon Leu-363 and Gly-364 of the YJL114W ORF.

Length:1,803
Mass (Da):207,710
GO

Sequence cautioni

The sequence DAA08687.2 differs from that shown. Reason: Frameshift at positions 226 and 240. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X67284 Genomic DNA. No translation available.
Z49389 Genomic DNA. Translation: CAA89408.1.
BK006943 Genomic DNA. Translation: DAA08687.2. Frameshift.
PIRiJC1482.
S31261.
RefSeqiNP_012422.2. NM_001181547.2.

Genome annotation databases

GeneIDi853329.
KEGGisce:YJL114W.

Keywords - Coding sequence diversityi

Ribosomal frameshifting

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X67284 Genomic DNA. No translation available.
Z49389 Genomic DNA. Translation: CAA89408.1.
BK006943 Genomic DNA. Translation: DAA08687.2. Frameshift.
PIRiJC1482.
S31261.
RefSeqiNP_012422.2. NM_001181547.2.

3D structure databases

ProteinModelPortaliP47023.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi33641. 6 interactions.
DIPiDIP-7219N.
IntActiP47023. 7 interactions.
MINTiMINT-390812.
STRINGi4932.YJL114W.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi853329.
KEGGisce:YJL114W.

Organism-specific databases

CYGDiYJL114w.
SGDiS000003650. YJL114W.

Phylogenomic databases

HOGENOMiHOG000155564.
InParanoidiP47023.
OrthoDBiEOG7G1VGM.

Miscellaneous databases

NextBioi973692.

Gene expression databases

GenevestigatoriP47023.

Family and domain databases

InterProiIPR001878. Znf_CCHC.
[Graphical view]
SMARTiSM00343. ZnF_C2HC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Ty4, a new retrotransposon from Saccharomyces cerevisiae, flanked by tau-elements."
    Janetzky B., Lehle L.
    J. Biol. Chem. 267:19798-19805(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. "Sequencing analysis of a 40.2 kb fragment of yeast chromosome X reveals 19 open reading frames including URA2 (5' end), TRK1, PBS2, SPT10, GCD14, RPE1, PHO86, NCA3, ASF1, CCT7, GZF3, two tRNA genes, three remnant delta elements and a Ty4 transposon."
    Cziepluch C., Kordes E., Pujol A., Jauniaux J.-C.
    Yeast 12:1471-1474(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 96604 / S288c / FY1679.
  3. "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."
    Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K.
    , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.
    EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. Cited for: GENOME REANNOTATION, SEQUENCE REVISION TO 226 AND 240.
    Strain: ATCC 204508 / S288c.
  5. "Transposable elements and genome organization: a comprehensive survey of retrotransposons revealed by the complete Saccharomyces cerevisiae genome sequence."
    Kim J.M., Vanguri S., Boeke J.D., Gabriel A., Voytas D.F.
    Genome Res. 8:464-478(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NOMENCLATURE.
  6. "Happy together: the life and times of Ty retrotransposons and their hosts."
    Lesage P., Todeschini A.L.
    Cytogenet. Genome Res. 110:70-90(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: REVIEW.

Entry informationi

Entry nameiYJ41A_YEAST
AccessioniPrimary (citable) accession number: P47023
Secondary accession number(s): D6VW71
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: January 7, 2015
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Retrotransposons are mobile genetic entities that are able to replicate via an RNA intermediate and a reverse transcription step. In contrast to retroviruses, retrotransposons are non-infectious, lack an envelope and remain intracellular. Ty4 retrotransposons belong to the copia elements (pseudoviridae).

Keywords - Technical termi

Complete proteome, Reference proteome, Transposable element

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome X
    Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.