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P47023

- YJ41A_YEAST

UniProt

P47023 - YJ41A_YEAST

Protein

Transposon Ty4-J Gag polyprotein

Gene

TY4A-J

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 89 (01 Oct 2014)
      Sequence version 1 (01 Feb 1996)
      Previous versions | rss
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    Functioni

    Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome.By similarity

    GO - Molecular functioni

    1. RNA binding Source: SGD
    2. zinc ion binding Source: InterPro

    GO - Biological processi

    1. transposition, RNA-mediated Source: SGD

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Transposon Ty4-J Gag polyprotein
    Short name:
    TY4A
    Short name:
    Transposon Ty4 protein A
    Gene namesi
    Name:TY4A-J
    Synonyms:YJLWTy4-1 GAG
    Ordered Locus Names:YJL114W
    ORF Names:J0775
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome X

    Organism-specific databases

    CYGDiYJL114w.
    SGDiS000003650. YJL114W.

    Subcellular locationi

    GO - Cellular componenti

    1. retrotransposon nucleocapsid Source: SGD

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 414414Transposon Ty4-J Gag polyproteinPRO_0000203501Add
    BLAST

    Expressioni

    Gene expression databases

    GenevestigatoriP47023.

    Interactioni

    Protein-protein interaction databases

    BioGridi33641. 6 interactions.
    DIPiDIP-7219N.
    IntActiP47023. 7 interactions.
    MINTiMINT-390812.
    STRINGi4932.YJL114W.

    Structurei

    3D structure databases

    ProteinModelPortaliP47023.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili39 – 11577Sequence AnalysisAdd
    BLAST

    Keywords - Domaini

    Coiled coil

    Phylogenomic databases

    HOGENOMiHOG000155564.
    OrthoDBiEOG7G1VGM.

    Family and domain databases

    InterProiIPR001878. Znf_CCHC.
    [Graphical view]
    SMARTiSM00343. ZnF_C2HC. 1 hit.
    [Graphical view]

    Sequences (2)i

    Sequence statusi: Complete.

    This entry describes 2 isoformsi produced by ribosomal frameshifting. Align

    Note: The Gag-Pol polyprotein is generated by a +1 ribosomal frameshift.

    Isoform Transposon Ty4-J Gag polyprotein (identifier: P47023-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MATPVRGETR NVIDDNISAR IQSKVKTNDT VRQTPSSLRK VSIKDEQVRQ    50
    YQRNLNRFKT ILNGLKAEEE KLSEADDIQM LAEKLLKLGE TIDKVENRIV 100
    DLVEKIQLLE TNENNNILHE HIDATGTYYL FDTLTSTNKR FYPKDCVFDY 150
    RTNNVENIPI LLNNFKKFIK KYQFDDVFEN DIIEIDPREN EILCKIIKEG 200
    LGESLDIMNT NTTDIFRIID GLKKQNIEVC MVEMSELEPG EKVLVDTTCR 250
    NSALLMNKLQ KLVLMEKWIF SKCCQDCPNL KDYLQEAIMG TLHESLRNSV 300
    KQRLYNIPHD VGIDHEEFLI NTVIETVIDL SPIADDQIEN SCMYCKSVFH 350
    CSINCKKKPN RELRPDSTNF SKTYYLQGAQ RQQPLKSSAK RTKVLEQDTK 400
    KVEQSVQQQK TGNY 414

    Note: Produced by conventional translation.

    Length:414
    Mass (Da):48,035
    Last modified:February 1, 1996 - v1
    Checksum:i541F3767BE5F8275
    GO
    Isoform Transposon Ty4-J Gag-Pol polyprotein (identifier: P47024-1) [UniParc]FASTAAdd to Basket

    The sequence of this isoform can be found in the external entry P47024.
    Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.

    Note: Produced by +1 ribosomal frameshifting between codon Leu-363 and Gly-364 of the YJL114W ORF.

    Length:1,803
    Mass (Da):207,710
    GO

    Sequence cautioni

    The sequence DAA08687.2 differs from that shown. Reason: Frameshift at positions 226 and 240.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X67284 Genomic DNA. No translation available.
    Z49389 Genomic DNA. Translation: CAA89408.1.
    BK006943 Genomic DNA. Translation: DAA08687.2. Frameshift.
    PIRiJC1482.
    S31261.
    RefSeqiNP_012422.2. NM_001181547.2.

    Genome annotation databases

    GeneIDi853329.
    KEGGisce:YJL114W.

    Keywords - Coding sequence diversityi

    Ribosomal frameshifting

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X67284 Genomic DNA. No translation available.
    Z49389 Genomic DNA. Translation: CAA89408.1 .
    BK006943 Genomic DNA. Translation: DAA08687.2 . Frameshift.
    PIRi JC1482.
    S31261.
    RefSeqi NP_012422.2. NM_001181547.2.

    3D structure databases

    ProteinModelPortali P47023.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 33641. 6 interactions.
    DIPi DIP-7219N.
    IntActi P47023. 7 interactions.
    MINTi MINT-390812.
    STRINGi 4932.YJL114W.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 853329.
    KEGGi sce:YJL114W.

    Organism-specific databases

    CYGDi YJL114w.
    SGDi S000003650. YJL114W.

    Phylogenomic databases

    HOGENOMi HOG000155564.
    OrthoDBi EOG7G1VGM.

    Miscellaneous databases

    NextBioi 973692.

    Gene expression databases

    Genevestigatori P47023.

    Family and domain databases

    InterProi IPR001878. Znf_CCHC.
    [Graphical view ]
    SMARTi SM00343. ZnF_C2HC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Ty4, a new retrotransposon from Saccharomyces cerevisiae, flanked by tau-elements."
      Janetzky B., Lehle L.
      J. Biol. Chem. 267:19798-19805(1992) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. "Sequencing analysis of a 40.2 kb fragment of yeast chromosome X reveals 19 open reading frames including URA2 (5' end), TRK1, PBS2, SPT10, GCD14, RPE1, PHO86, NCA3, ASF1, CCT7, GZF3, two tRNA genes, three remnant delta elements and a Ty4 transposon."
      Cziepluch C., Kordes E., Pujol A., Jauniaux J.-C.
      Yeast 12:1471-1474(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 96604 / S288c / FY1679.
    3. "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."
      Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K.
      , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.
      EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    4. Cited for: GENOME REANNOTATION, SEQUENCE REVISION TO 226 AND 240.
      Strain: ATCC 204508 / S288c.
    5. "Transposable elements and genome organization: a comprehensive survey of retrotransposons revealed by the complete Saccharomyces cerevisiae genome sequence."
      Kim J.M., Vanguri S., Boeke J.D., Gabriel A., Voytas D.F.
      Genome Res. 8:464-478(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NOMENCLATURE.
    6. "Happy together: the life and times of Ty retrotransposons and their hosts."
      Lesage P., Todeschini A.L.
      Cytogenet. Genome Res. 110:70-90(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: REVIEW.

    Entry informationi

    Entry nameiYJ41A_YEAST
    AccessioniPrimary (citable) accession number: P47023
    Secondary accession number(s): D6VW71
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1996
    Last sequence update: February 1, 1996
    Last modified: October 1, 2014
    This is version 89 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Retrotransposons are mobile genetic entities that are able to replicate via an RNA intermediate and a reverse transcription step. In contrast to retroviruses, retrotransposons are non-infectious, lack an envelope and remain intracellular. Ty4 retrotransposons belong to the copia elements (pseudoviridae).

    Keywords - Technical termi

    Complete proteome, Reference proteome, Transposable element

    Documents

    1. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    2. Yeast chromosome X
      Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

    External Data

    Dasty 3