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P47015 (AIM23_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 85. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Altered inheritance of mitochondria protein 23, mitochondrial
Gene names
Name:AIM23
Ordered Locus Names:YJL131C
ORF Names:J0682
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length356 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Mitochondrion Ref.5 Ref.7.

Disruption phenotype

Increases frequency of mitochondrial genome loss. Ref.8

Miscellaneous

Present with 319 molecules/cell in log phase SD medium.

Sequence similarities

Belongs to the AIM23 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 3232Mitochondrion Potential
Chain33 – 356324Altered inheritance of mitochondria protein 23, mitochondrial
PRO_0000203039

Sequences

Sequence LengthMass (Da)Tools
P47015 [UniParc].

Last modified February 1, 1996. Version 1.
Checksum: BCF907223417B6C2

FASTA35641,461
        10         20         30         40         50         60 
MLKVPLSDVL SQKMLFLKSF RYFHCTKYFS RDNASSTTDI FRNAMKRKRE LANLKEQSHG 

        70         80         90        100        110        120 
NVARNAAFPK EYIKRPKQVP RNATNRKKIL ITWSTGTDRA KEAANSVVSE IFKKNHKGNI 

       130        140        150        160        170        180 
KVVDPTTHRI EASNIRYFAK GIDLDKVGLS IVNVEQIDNE NQIPLVKIVE SRVALKKYSD 

       190        200        210        220        230        240 
FLAKKKEKEL MELGVLNKSY KNLVTDKKED NLKHIKISWQ IESDDLKRQK AHEIVSLLKK 

       250        260        270        280        290        300 
GNKVTLYLDD KNNINSNNWL ENFEELDRSQ KGEPPRLPES VFQKRAAVLE TLKEIVSEYA 

       310        320        330        340        350 
NDPVLLGNMN SKMIMKLIPK DVKPQNNDKR ALKELRKKER QEKLQKRIQR KKMNEM 

« Hide

References

« Hide 'large scale' references
[1]"Sequence analysis of a 40.7 kb segment from the left arm of yeast chromosome X reveals 14 known genes and 13 new open reading frames including homologues of genes clustered on the right arm of chromosome XI."
Katsoulou C., Tzermia M., Tavernarakis N., Alexandraki D.
Yeast 12:787-797(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 96604 / S288c / FY1679.
[2]"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."
Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K. expand/collapse author list , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.
EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"Organization of the yeast URA2 gene: identification of a defective dihydroorotase-like domain in the multifunctional carbamoylphosphate synthetase-aspartate transcarbamylase complex."
Souciet J.-L., Nagy M., le Gouar M., Lacroute F., Potier S.
Gene 79:59-70(1989) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-124.
Strain: ATCC 28383 / FL100 / VTT C-80102.
[5]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[6]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[7]"Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics."
Reinders J., Zahedi R.P., Pfanner N., Meisinger C., Sickmann A.
J. Proteome Res. 5:1543-1554(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[8]"Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis."
Hess D.C., Myers C.L., Huttenhower C., Hibbs M.A., Hayes A.P., Paw J., Clore J.J., Mendoza R.M., Luis B.S., Nislow C., Giaever G., Costanzo M., Troyanskaya O.G., Caudy A.A.
PLoS Genet. 5:E1000407-E1000407(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: DISRUPTION PHENOTYPE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X87371 Genomic DNA. Translation: CAA60824.1.
Z49406 Genomic DNA. Translation: CAA89426.1.
M27174 Genomic DNA. No translation available.
BK006943 Genomic DNA. Translation: DAA08670.1.
PIRS55181.
RefSeqNP_012404.1. NM_001181564.1.

3D structure databases

ProteinModelPortalP47015.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid33625. 5 interactions.
DIPDIP-5684N.
IntActP47015. 1 interaction.
MINTMINT-491609.
STRING4932.YJL131C.

Proteomic databases

PaxDbP47015.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYJL131C; YJL131C; YJL131C.
GeneID853310.
KEGGsce:YJL131C.

Organism-specific databases

CYGDYJL131c.
SGDS000003667. AIM23.

Phylogenomic databases

eggNOGNOG47128.
OMAKHIKISW.
OrthoDBEOG7SBNZP.

Enzyme and pathway databases

BioCycYEAST:G3O-31580-MONOMER.

Gene expression databases

GenevestigatorP47015.

Family and domain databases

Gene3D3.30.110.10. 1 hit.
InterProIPR019815. Translation_initiation_fac_3_C.
[Graphical view]
ProtoNetSearch...

Other

NextBio973645.

Entry information

Entry nameAIM23_YEAST
AccessionPrimary (citable) accession number: P47015
Secondary accession number(s): D6VW54
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: April 16, 2014
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome X

Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families