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P47015

- AIM23_YEAST

UniProt

P47015 - AIM23_YEAST

Protein

Altered inheritance of mitochondria protein 23, mitochondrial

Gene

AIM23

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 88 (01 Oct 2014)
      Sequence version 1 (01 Feb 1996)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ribosome binding Source: SGD
    2. translation initiation factor activity Source: SGD

    GO - Biological processi

    1. formation of translation initiation complex Source: SGD
    2. regulation of translational initiation Source: SGD

    Enzyme and pathway databases

    BioCyciYEAST:G3O-31580-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Altered inheritance of mitochondria protein 23, mitochondrial
    Gene namesi
    Name:AIM23
    Ordered Locus Names:YJL131C
    ORF Names:J0682
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome X

    Organism-specific databases

    CYGDiYJL131c.
    SGDiS000003667. AIM23.

    Subcellular locationi

    Mitochondrion 2 Publications

    GO - Cellular componenti

    1. mitochondrion Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Mitochondrion

    Pathology & Biotechi

    Disruption phenotypei

    Increases frequency of mitochondrial genome loss.1 Publication

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transit peptidei1 – 3232MitochondrionSequence AnalysisAdd
    BLAST
    Chaini33 – 356324Altered inheritance of mitochondria protein 23, mitochondrialPRO_0000203039Add
    BLAST

    Proteomic databases

    MaxQBiP47015.
    PaxDbiP47015.

    Expressioni

    Gene expression databases

    GenevestigatoriP47015.

    Interactioni

    Protein-protein interaction databases

    BioGridi33625. 5 interactions.
    DIPiDIP-5684N.
    IntActiP47015. 1 interaction.
    MINTiMINT-491609.
    STRINGi4932.YJL131C.

    Structurei

    3D structure databases

    ProteinModelPortaliP47015.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the AIM23 family.Curated

    Keywords - Domaini

    Transit peptide

    Phylogenomic databases

    eggNOGiNOG47128.
    OMAiKHIKISW.
    OrthoDBiEOG7SBNZP.

    Family and domain databases

    Gene3Di3.30.110.10. 1 hit.
    InterProiIPR029427. AIM23.
    IPR019815. Translation_initiation_fac_3_C.
    [Graphical view]
    PfamiPF14877. mIF3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P47015-1 [UniParc]FASTAAdd to Basket

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    MLKVPLSDVL SQKMLFLKSF RYFHCTKYFS RDNASSTTDI FRNAMKRKRE    50
    LANLKEQSHG NVARNAAFPK EYIKRPKQVP RNATNRKKIL ITWSTGTDRA 100
    KEAANSVVSE IFKKNHKGNI KVVDPTTHRI EASNIRYFAK GIDLDKVGLS 150
    IVNVEQIDNE NQIPLVKIVE SRVALKKYSD FLAKKKEKEL MELGVLNKSY 200
    KNLVTDKKED NLKHIKISWQ IESDDLKRQK AHEIVSLLKK GNKVTLYLDD 250
    KNNINSNNWL ENFEELDRSQ KGEPPRLPES VFQKRAAVLE TLKEIVSEYA 300
    NDPVLLGNMN SKMIMKLIPK DVKPQNNDKR ALKELRKKER QEKLQKRIQR 350
    KKMNEM 356
    Length:356
    Mass (Da):41,461
    Last modified:February 1, 1996 - v1
    Checksum:iBCF907223417B6C2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X87371 Genomic DNA. Translation: CAA60824.1.
    Z49406 Genomic DNA. Translation: CAA89426.1.
    M27174 Genomic DNA. No translation available.
    BK006943 Genomic DNA. Translation: DAA08670.1.
    PIRiS55181.
    RefSeqiNP_012404.1. NM_001181564.1.

    Genome annotation databases

    EnsemblFungiiYJL131C; YJL131C; YJL131C.
    GeneIDi853310.
    KEGGisce:YJL131C.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X87371 Genomic DNA. Translation: CAA60824.1 .
    Z49406 Genomic DNA. Translation: CAA89426.1 .
    M27174 Genomic DNA. No translation available.
    BK006943 Genomic DNA. Translation: DAA08670.1 .
    PIRi S55181.
    RefSeqi NP_012404.1. NM_001181564.1.

    3D structure databases

    ProteinModelPortali P47015.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 33625. 5 interactions.
    DIPi DIP-5684N.
    IntActi P47015. 1 interaction.
    MINTi MINT-491609.
    STRINGi 4932.YJL131C.

    Proteomic databases

    MaxQBi P47015.
    PaxDbi P47015.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YJL131C ; YJL131C ; YJL131C .
    GeneIDi 853310.
    KEGGi sce:YJL131C.

    Organism-specific databases

    CYGDi YJL131c.
    SGDi S000003667. AIM23.

    Phylogenomic databases

    eggNOGi NOG47128.
    OMAi KHIKISW.
    OrthoDBi EOG7SBNZP.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-31580-MONOMER.

    Miscellaneous databases

    NextBioi 973645.

    Gene expression databases

    Genevestigatori P47015.

    Family and domain databases

    Gene3Di 3.30.110.10. 1 hit.
    InterProi IPR029427. AIM23.
    IPR019815. Translation_initiation_fac_3_C.
    [Graphical view ]
    Pfami PF14877. mIF3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence analysis of a 40.7 kb segment from the left arm of yeast chromosome X reveals 14 known genes and 13 new open reading frames including homologues of genes clustered on the right arm of chromosome XI."
      Katsoulou C., Tzermia M., Tavernarakis N., Alexandraki D.
      Yeast 12:787-797(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 96604 / S288c / FY1679.
    2. "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."
      Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K.
      , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.
      EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    3. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    4. "Organization of the yeast URA2 gene: identification of a defective dihydroorotase-like domain in the multifunctional carbamoylphosphate synthetase-aspartate transcarbamylase complex."
      Souciet J.-L., Nagy M., le Gouar M., Lacroute F., Potier S.
      Gene 79:59-70(1989) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-124.
      Strain: ATCC 28383 / FL100 / VTT C-80102.
    5. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    6. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
    7. "Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics."
      Reinders J., Zahedi R.P., Pfanner N., Meisinger C., Sickmann A.
      J. Proteome Res. 5:1543-1554(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    8. "Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis."
      Hess D.C., Myers C.L., Huttenhower C., Hibbs M.A., Hayes A.P., Paw J., Clore J.J., Mendoza R.M., Luis B.S., Nislow C., Giaever G., Costanzo M., Troyanskaya O.G., Caudy A.A.
      PLoS Genet. 5:E1000407-E1000407(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: DISRUPTION PHENOTYPE.

    Entry informationi

    Entry nameiAIM23_YEAST
    AccessioniPrimary (citable) accession number: P47015
    Secondary accession number(s): D6VW54
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1996
    Last sequence update: February 1, 1996
    Last modified: October 1, 2014
    This is version 88 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Present with 319 molecules/cell in log phase SD medium.1 Publication

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    3. Yeast chromosome X
      Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

    External Data

    Dasty 3