P46998 (FMP33_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Mitochondrial membrane protein FMP33

Gene names

Name:	FMP33
Ordered Locus Names:	YJL161W
ORF Names:	J0552

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	180 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location	Mitochondrion membrane; Multi-pass membrane protein Ref.3 Ref.4.
Induction	By cell wall perturbation. Ref.5

Ontologies

Keywords
Cellular component	Membrane Mitochondrion
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW mitochondrial membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 180	180	Mitochondrial membrane protein FMP33		PRO_0000203028
Regions
	Transmembrane	34 – 54	21	Helical; Potential
	Transmembrane	121 – 141	21	Helical; Potential
	Transmembrane	145 – 165	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	P46998 [UniParc]. Last modified February 1, 1996. Version 1. Checksum: F4F53250CF0C6F0B	FASTA	180	20,185
	10 20 30 40 50 60 MLYTRLLRHN SQFTKFSGTS PNLGSKPLFS KGNLYTSLLV TTLYGTGLAC LYLESNSLNK 70 80 90 100 110 120 SKEQEDPHAI AEDDIVNIVH DAPNRIFKPA LDTYQEKELD LQKSDLHKVL HSLTYSDVSQ 130 140 150 160 170 180 FSIVWGFLIQ LSSLIGNSTL GKKSILYKGS VVSVLGFPPL IYMALKLRMK QLEKAGVRFE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X." Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K. , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L. EMBO J. 15:2031-2049(1996) [PubMed: 8641269] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	"Global analysis of protein localization in budding yeast." Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K. Nature 425:686-691(2003) [PubMed: 14562095] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[4]	"The proteome of Saccharomyces cerevisiae mitochondria." Sickmann A., Reinders J., Wagner Y., Joppich C., Zahedi R.P., Meyer H.E., Schoenfisch B., Perschil I., Chacinska A., Guiard B., Rehling P., Pfanner N., Meisinger C. Proc. Natl. Acad. Sci. U.S.A. 100:13207-13212(2003) [PubMed: 14576278] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS], MASS SPECTROMETRY. Strain: ATCC 76625 / YPH499.
[5]	"Characterization of the transcriptional response to cell wall stress in Saccharomyces cerevisiae." Boorsma A., de Nobel H., ter Riet B., Bargmann B., Brul S., Hellingwerf K.J., Klis F.M. Yeast 21:413-427(2004) [PubMed: 15116342] [Abstract] Cited for: INDUCTION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z49436 Genomic DNA. Translation: CAA89456.1. BK006943 Genomic DNA. Translation: DAA08642.1.
PIR	S56944.
RefSeq	NP_012374.1. NM_001181594.1.
3D structure databases
ProteinModelPortal	P46998.
ModBase	Search...
Protein-protein interaction databases
STRING	P46998.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YJL161W; YJL161W; YJL161W.
GeneID	853279.
KEGG	sce:YJL161W.
NMPDR	fig|4932.3.peg.3338.
Organism-specific databases
CYGD	YJL161w.
SGD	S000003697. FMP33.
Phylogenomic databases
eggNOG	fuNOG15660.
OMA	SEIQNAS.
OrthoDB	EOG4PK5JR.
Gene expression databases
ArrayExpress	P46998.
Genevestigator	P46998.
GermOnline	YJL161W. Saccharomyces cerevisiae.
Family and domain databases
ProtoNet	Search...
Other
NextBio	973567.

Entry information

Entry name

FMP33_YEAST

Accession

Primary (citable) accession number: P46998
Secondary accession number(s): D6VW26

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1996
Last sequence update:	February 1, 1996
Last modified:	December 14, 2011
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program