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P46997

- JJJ2_YEAST

UniProt

P46997 - JJJ2_YEAST

Protein

J protein JJJ2

Gene

JJJ2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 102 (01 Oct 2014)
      Sequence version 2 (20 May 2008)
      Previous versions | rss
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    Functioni

    Keywords - Molecular functioni

    Chaperone

    Enzyme and pathway databases

    BioCyciYEAST:G3O-31602-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    J protein JJJ2
    Gene namesi
    Name:JJJ2
    Ordered Locus Names:YJL162C
    ORF Names:J0549
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome X

    Organism-specific databases

    SGDiS000003698. JJJ2.

    Subcellular locationi

    Cytoplasm 1 Publication. Nucleus 1 Publication

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm, Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 583583J protein JJJ2PRO_0000071142Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei229 – 2291Phosphoserine1 Publication

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    MaxQBiP46997.
    PaxDbiP46997.

    Expressioni

    Gene expression databases

    GenevestigatoriP46997.

    Interactioni

    Protein-protein interaction databases

    BioGridi33597. 7 interactions.
    DIPiDIP-4033N.
    IntActiP46997. 1 interaction.
    MINTiMINT-412025.
    STRINGi4932.YJL162C.

    Structurei

    3D structure databases

    ProteinModelPortaliP46997.
    SMRiP46997. Positions 15-64.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini11 – 7969JPROSITE-ProRule annotationAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi232 – 2365Poly-Glu
    Compositional biasi240 – 25213Poly-GlnAdd
    BLAST

    Sequence similaritiesi

    Contains 1 J domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG2214.
    OMAiEQPYGFG.
    OrthoDBiEOG7M3J9N.

    Family and domain databases

    Gene3Di1.10.287.110. 1 hit.
    InterProiIPR001623. DnaJ_domain.
    IPR018253. DnaJ_domain_CS.
    [Graphical view]
    PfamiPF00226. DnaJ. 1 hit.
    [Graphical view]
    PRINTSiPR00625. JDOMAIN.
    SMARTiSM00271. DnaJ. 1 hit.
    [Graphical view]
    SUPFAMiSSF46565. SSF46565. 1 hit.
    PROSITEiPS00636. DNAJ_1. 1 hit.
    PS50076. DNAJ_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P46997-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSQVIEPQLD RTTYYSILGL TSNATSSEVH KSYLKLARLL HPDKTKSDKS    50
    EELFKAVVHA HSILTDEDQK LRYDRDLKIK GLHTYQPKKN CHIFKTKAKE 100
    SQGASPTLGQ SEAYHRQNKP YEQQPYGFGV GKKMTSSSKS KVPIFKSFNL 150
    KSYQRNHYYS SKKERKHGSP DIDSLFHETN GASKVRMTDA GKMDTNSQFQ 200
    EIWEILGKNA YTHKSYSEDP NSCLGSALSD HEEEEEAGKQ QQQQQQQQQQ 250
    QQHYGMTSKS SSPDEEKKNN KEPKRESRVS PEENGEEETG HKQFKLPKTS 300
    TFSSGSHDSN LQSPFYNHEY RHYARSKFEC KNQFRKSVSP IKEIPATTSA 350
    NEGWNILRDI IEKLNISNVD DRNKDLLFRR DEIGDKNHSD SIDIENLSIK 400
    EPKGMKRRKK DDISLEELFQ SLPREKDYFM MDAINDSLES INLFKKPKTT 450
    QSHEQGGTFA QAESNRAKFK PLLEQCGITP EILDLEIPEI PEFDAVADLE 500
    TLKLNVQLFN NQCNKLKETI HQVSLQRLRA DTQFSDMLTQ KQSIMVWKTY 550
    LEFDKSLMDK LNILQERQMQ VIKIFSERCD GKV 583
    Length:583
    Mass (Da):67,389
    Last modified:May 20, 2008 - v2
    Checksum:i6CBB8ED37F5F340B
    GO

    Sequence cautioni

    The sequence CAA89457.1 differs from that shown. Reason: Erroneous termination at position 483. Translated as Leu.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z49437 Genomic DNA. Translation: CAA89457.1. Sequence problems.
    BK006943 Genomic DNA. Translation: DAA08641.1.
    PIRiS56945.
    RefSeqiNP_012373.2. NM_001181595.1.

    Genome annotation databases

    EnsemblFungiiYJL162C; YJL162C; YJL162C.
    GeneIDi853277.
    KEGGisce:YJL162C.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z49437 Genomic DNA. Translation: CAA89457.1 . Sequence problems.
    BK006943 Genomic DNA. Translation: DAA08641.1 .
    PIRi S56945.
    RefSeqi NP_012373.2. NM_001181595.1.

    3D structure databases

    ProteinModelPortali P46997.
    SMRi P46997. Positions 15-64.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 33597. 7 interactions.
    DIPi DIP-4033N.
    IntActi P46997. 1 interaction.
    MINTi MINT-412025.
    STRINGi 4932.YJL162C.

    Proteomic databases

    MaxQBi P46997.
    PaxDbi P46997.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YJL162C ; YJL162C ; YJL162C .
    GeneIDi 853277.
    KEGGi sce:YJL162C.

    Organism-specific databases

    SGDi S000003698. JJJ2.

    Phylogenomic databases

    eggNOGi COG2214.
    OMAi EQPYGFG.
    OrthoDBi EOG7M3J9N.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-31602-MONOMER.

    Miscellaneous databases

    NextBioi 973562.

    Gene expression databases

    Genevestigatori P46997.

    Family and domain databases

    Gene3Di 1.10.287.110. 1 hit.
    InterProi IPR001623. DnaJ_domain.
    IPR018253. DnaJ_domain_CS.
    [Graphical view ]
    Pfami PF00226. DnaJ. 1 hit.
    [Graphical view ]
    PRINTSi PR00625. JDOMAIN.
    SMARTi SM00271. DnaJ. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46565. SSF46565. 1 hit.
    PROSITEi PS00636. DNAJ_1. 1 hit.
    PS50076. DNAJ_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."
      Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K.
      , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.
      EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. Cited for: GENOME REANNOTATION, SEQUENCE REVISION TO 433 AND 483.
      Strain: ATCC 204508 / S288c.
    3. "Sequencing and comparison of yeast species to identify genes and regulatory elements."
      Kellis M., Patterson N., Endrizzi M., Birren B.W., Lander E.S.
      Nature 423:241-254(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION OF PROBABLE SEQUENCE ERRORS.
    4. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    5. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
    6. "The J-protein family: modulating protein assembly, disassembly and translocation."
      Walsh P., Bursac D., Law Y.C., Cyr D., Lithgow T.
      EMBO Rep. 5:567-571(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE NAME.
    7. "A multidimensional chromatography technology for in-depth phosphoproteome analysis."
      Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
      Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-229, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    8. "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
      Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
      Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiJJJ2_YEAST
    AccessioniPrimary (citable) accession number: P46997
    Secondary accession number(s): D6VW25
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1996
    Last sequence update: May 20, 2008
    Last modified: October 1, 2014
    This is version 102 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Present with 184 molecules/cell in log phase SD medium.1 Publication

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    3. Yeast chromosome X
      Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

    External Data

    Dasty 3