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Protein

J protein JJJ2

Gene

JJJ2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Keywords - Molecular functioni

Chaperone

Enzyme and pathway databases

BioCyciYEAST:G3O-31602-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
J protein JJJ2
Gene namesi
Name:JJJ2
Ordered Locus Names:YJL162C
ORF Names:J0549
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311 Componenti: Chromosome X

Organism-specific databases

EuPathDBiFungiDB:YJL162C.
SGDiS000003698. JJJ2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 583583J protein JJJ2PRO_0000071142Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei229 – 2291Phosphoserine1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP46997.
PaxDbiP46997.

Interactioni

Protein-protein interaction databases

BioGridi33597. 7 interactions.
DIPiDIP-4033N.
IntActiP46997. 1 interaction.
MINTiMINT-412025.

Structurei

3D structure databases

ProteinModelPortaliP46997.
SMRiP46997. Positions 15-64.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini11 – 7969JPROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi232 – 2365Poly-Glu
Compositional biasi240 – 25213Poly-GlnAdd
BLAST

Sequence similaritiesi

Contains 1 J domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG2214.
InParanoidiP46997.
OMAiEQPYGFG.
OrthoDBiEOG7M3J9N.

Family and domain databases

Gene3Di1.10.287.110. 1 hit.
InterProiIPR001623. DnaJ_domain.
IPR018253. DnaJ_domain_CS.
[Graphical view]
PfamiPF00226. DnaJ. 1 hit.
[Graphical view]
PRINTSiPR00625. JDOMAIN.
SMARTiSM00271. DnaJ. 1 hit.
[Graphical view]
SUPFAMiSSF46565. SSF46565. 1 hit.
PROSITEiPS00636. DNAJ_1. 1 hit.
PS50076. DNAJ_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P46997-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQVIEPQLD RTTYYSILGL TSNATSSEVH KSYLKLARLL HPDKTKSDKS
60 70 80 90 100
EELFKAVVHA HSILTDEDQK LRYDRDLKIK GLHTYQPKKN CHIFKTKAKE
110 120 130 140 150
SQGASPTLGQ SEAYHRQNKP YEQQPYGFGV GKKMTSSSKS KVPIFKSFNL
160 170 180 190 200
KSYQRNHYYS SKKERKHGSP DIDSLFHETN GASKVRMTDA GKMDTNSQFQ
210 220 230 240 250
EIWEILGKNA YTHKSYSEDP NSCLGSALSD HEEEEEAGKQ QQQQQQQQQQ
260 270 280 290 300
QQHYGMTSKS SSPDEEKKNN KEPKRESRVS PEENGEEETG HKQFKLPKTS
310 320 330 340 350
TFSSGSHDSN LQSPFYNHEY RHYARSKFEC KNQFRKSVSP IKEIPATTSA
360 370 380 390 400
NEGWNILRDI IEKLNISNVD DRNKDLLFRR DEIGDKNHSD SIDIENLSIK
410 420 430 440 450
EPKGMKRRKK DDISLEELFQ SLPREKDYFM MDAINDSLES INLFKKPKTT
460 470 480 490 500
QSHEQGGTFA QAESNRAKFK PLLEQCGITP EILDLEIPEI PEFDAVADLE
510 520 530 540 550
TLKLNVQLFN NQCNKLKETI HQVSLQRLRA DTQFSDMLTQ KQSIMVWKTY
560 570 580
LEFDKSLMDK LNILQERQMQ VIKIFSERCD GKV
Length:583
Mass (Da):67,389
Last modified:May 20, 2008 - v2
Checksum:i6CBB8ED37F5F340B
GO

Sequence cautioni

The sequence CAA89457.1 differs from that shown. Reason: Erroneous termination at position 483. Translated as Leu.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49437 Genomic DNA. Translation: CAA89457.1. Sequence problems.
BK006943 Genomic DNA. Translation: DAA08641.1.
PIRiS56945.
RefSeqiNP_012373.2. NM_001181595.1.

Genome annotation databases

EnsemblFungiiYJL162C; YJL162C; YJL162C.
GeneIDi853277.
KEGGisce:YJL162C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49437 Genomic DNA. Translation: CAA89457.1. Sequence problems.
BK006943 Genomic DNA. Translation: DAA08641.1.
PIRiS56945.
RefSeqiNP_012373.2. NM_001181595.1.

3D structure databases

ProteinModelPortaliP46997.
SMRiP46997. Positions 15-64.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi33597. 7 interactions.
DIPiDIP-4033N.
IntActiP46997. 1 interaction.
MINTiMINT-412025.

Proteomic databases

MaxQBiP46997.
PaxDbiP46997.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYJL162C; YJL162C; YJL162C.
GeneIDi853277.
KEGGisce:YJL162C.

Organism-specific databases

EuPathDBiFungiDB:YJL162C.
SGDiS000003698. JJJ2.

Phylogenomic databases

eggNOGiCOG2214.
InParanoidiP46997.
OMAiEQPYGFG.
OrthoDBiEOG7M3J9N.

Enzyme and pathway databases

BioCyciYEAST:G3O-31602-MONOMER.

Miscellaneous databases

NextBioi973562.
PROiP46997.

Family and domain databases

Gene3Di1.10.287.110. 1 hit.
InterProiIPR001623. DnaJ_domain.
IPR018253. DnaJ_domain_CS.
[Graphical view]
PfamiPF00226. DnaJ. 1 hit.
[Graphical view]
PRINTSiPR00625. JDOMAIN.
SMARTiSM00271. DnaJ. 1 hit.
[Graphical view]
SUPFAMiSSF46565. SSF46565. 1 hit.
PROSITEiPS00636. DNAJ_1. 1 hit.
PS50076. DNAJ_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."
    Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K.
    , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.
    EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION, SEQUENCE REVISION TO 433 AND 483.
    Strain: ATCC 204508 / S288c.
  3. "Sequencing and comparison of yeast species to identify genes and regulatory elements."
    Kellis M., Patterson N., Endrizzi M., Birren B.W., Lander E.S.
    Nature 423:241-254(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION OF PROBABLE SEQUENCE ERRORS.
  4. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  5. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  6. "The J-protein family: modulating protein assembly, disassembly and translocation."
    Walsh P., Bursac D., Law Y.C., Cyr D., Lithgow T.
    EMBO Rep. 5:567-571(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE NAME.
  7. "A multidimensional chromatography technology for in-depth phosphoproteome analysis."
    Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
    Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-229, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  8. "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
    Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
    Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiJJJ2_YEAST
AccessioniPrimary (citable) accession number: P46997
Secondary accession number(s): D6VW25
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: May 20, 2008
Last modified: July 22, 2015
This is version 107 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 184 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome X
    Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.