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P46996 (YJQ3_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Uncharacterized membrane protein YJL163C
Gene names
Ordered Locus Names:YJL163C
ORF Names:J0544
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces ›

Protein attributes

Sequence length555 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Membrane; Multi-pass membrane protein.

Ontologies

Keywords
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix
   PTMPhosphoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtransmembrane transport

Inferred from electronic annotation. Source: InterPro

   Cellular_componentintegral to membrane

Inferred from sequence model PubMed 12192589. Source: SGD

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 555555Uncharacterized membrane protein YJL163C
PRO_0000203027

Regions

Topological domain1 – 8383Extracellular Potential
Transmembrane84 – 10421Helical; Potential
Topological domain105 – 12521Cytoplasmic Potential
Transmembrane126 – 14621Helical; Potential
Topological domain147 – 18842Extracellular Potential
Transmembrane189 – 20921Helical; Potential
Topological domain210 – 22920Cytoplasmic Potential
Transmembrane230 – 25021Helical; Potential
Topological domain251 – 2577Extracellular Potential
Transmembrane258 – 27821Helical; Potential
Topological domain279 – 35678Cytoplasmic Potential
Transmembrane357 – 37721Helical; Potential
Topological domain378 – 3869Extracellular Potential
Transmembrane387 – 40721Helical; Potential
Topological domain408 – 42821Cytoplasmic Potential
Transmembrane429 – 44921Helical; Potential
Topological domain450 – 45910Extracellular Potential
Transmembrane460 – 48021Helical; Potential
Topological domain481 – 49111Cytoplasmic Potential
Transmembrane492 – 51221Helical; Potential
Topological domain513 – 52311Extracellular Potential
Transmembrane524 – 54421Helical; Potential
Topological domain545 – 55511Cytoplasmic Potential

Amino acid modifications

Modified residue611Phosphoserine Ref.4
Modified residue641Phosphoserine Ref.4

Sequences

Sequence LengthMass (Da)Tools
P46996 [UniParc].

Last modified February 1, 1996. Version 1.
Checksum: A72400A0BB80A533

FASTA55561,525
        10         20         30         40         50         60 
MSNEDETTRL MSSDEMDYLL ETAGINALEE IISQNDSTGI NLDTNETAQD SSYDSIRRSP 

        70         80         90        100        110        120 
SILSVAKSVE GEHGRRKLLC LYGLVMIICI AESISMTATI PLVMDKVAEG ISDENGHYDS 

       130        140        150        160        170        180 
VAVQTIVSSI SSSTMMIAGA ISIFMAGKWG ELSDRIGRVR VFKYMSGIRV IGLLTHVFTL 

       190        200        210        220        230        240 
SSKMKYHKWA IVLTACIVPS FGGLFALVAN GNSYVSDIVK TEHRMVTIGI MMSCIYATMG 

       250        260        270        280        290        300 
VGPMFGSFLV KWTHGNGFIP IYTSIAFVIL ALIICETIMV EPRHETQMAH SQSTYTKRRE 

       310        320        330        340        350        360 
KLRSQSGSDD ARNYQSVTYG KFQIMRLMDL LAPVKKLWLK PDSAGSLVPR HTVILLIVLD 

       370        380        390        400        410        420 
ILFVCGTTSC MPALILFSTY EYKWHAVELG YFISILGIGR GVVLLVVSPT LLYTLKRIYQ 

       430        440        450        460        470        480 
HLNHSIDKID IFCIQFSMIV ITLSLFVMIR FGEKTPTSMI IFALLQALSA FCSPTLQSGI 

       490        500        510        520        530        540 
IKYTSKKHTG EMFGAMALVR SCVMLVIPPI LLKLYGSTVS VNPSLFMYIP FSTSIVAILL 

       550 
TFFLRIYKNP PLDGP

« Hide

References

« Hide 'large scale' references
[1]"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."
Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K. expand/collapse author list , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.
EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 96604 / S288c / FY1679.
[2]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"A global topology map of the Saccharomyces cerevisiae membrane proteome."
Kim H., Melen K., Oesterberg M., von Heijne G.
Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
Strain: ATCC 208353 / W303-1A.
[4]"Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases."
Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H.
Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-61 AND SER-64, MASS SPECTROMETRY.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		Z49438 Genomic DNA. Translation: CAA89458.1.
BK006943 Genomic DNA. Translation: DAA08640.1.
PIRS56946.
RefSeqNP_012372.1. NM_001181596.1.

3D structure databases

ProteinModelPortalP46996.
ModBaseSearch...

Protein-protein interaction databases

DIPDIP-8000N.
STRING4932.YJL163C.

Proteomic databases

PaxDbP46996.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYJL163C; YJL163C; YJL163C.
GeneID853276.
KEGGsce:YJL163C.

Organism-specific databases

CYGDYJL163c.
SGDS000003699. YJL163C.

Phylogenomic databases

eggNOGNOG318220.
HOGENOMHOG000142024.
OMAHSYASDC.
OrthoDBEOG4GF6Q1.

Gene expression databases

GenevestigatorP46996.
GermOnlineYJL163C. Saccharomyces cerevisiae.

Family and domain databases

InterProIPR011701. MFS.
IPR016196. MFS_dom_general_subst_transpt.
[Graphical view]
PfamPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMSSF103473. MFS_gen_substrate_transporter. 1 hit.
ProtoNetSearch...

Other

NextBio973559.

Entry information

Entry nameYJQ3_YEAST
AccessionPrimary (citable) accession number: P46996
Secondary accession number(s): D6VW24
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: April 3, 2013
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

Yeast chromosome X

Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents