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P46973 (HIT1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 91. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein HIT1
Gene names
Name:HIT1
Ordered Locus Names:YJR055W
ORF Names:J1705
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length164 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Miscellaneous

Present with 2730 molecules/cell in log phase SD medium.

Sequence similarities

Contains 1 HIT-type zinc finger.

Ontologies

Keywords
   DomainZinc-finger
   LigandMetal-binding
Zinc
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 164164Protein HIT1
PRO_0000173556

Regions

Zinc finger8 – 4942HIT-type

Experimental info

Sequence conflict36 – 372AA → RR in BAA01878. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P46973 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: EAC6ABB5457F87AA

FASTA16418,376
        10         20         30         40         50         60 
MVSSAVKCGI CRGVDGKYKC PKCGVRYCSL KCYKDAAKHV HKESEQPRAG TEANVEVVNN 

        70         80         90        100        110        120 
DKIINSSLAM NKTLKTKAFD DIYQNSAELQ ELLKYNTVKF HLAKVYRILS STVNDGSSGK 

       130        140        150        160 
MNSDLQKELA VNYLNTLRYG GIHYNEAIEE FCQILLDKLN AVKK 

« Hide

References

« Hide 'large scale' references
[1]"Ty element-induced temperature-sensitive mutations of Saccharomyces cerevisiae."
Kawakami K., Shafer B.K., Garfinkel D.J., Strathern J.N., Nakamura Y.
Genetics 131:821-832(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Analysis of a 62 kb DNA sequence of chromosome X reveals 36 open reading frames and a gene cluster with a counterpart on chromosome XI."
Huang M.-E., Manus V., Chuat J.-C., Galibert F.
Yeast 12:869-875(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."
Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K. expand/collapse author list , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.
EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[4]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[5]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[6]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D11103 Genomic DNA. Translation: BAA01878.1.
Z49555 Genomic DNA. Translation: CAA89583.1.
L47993 Genomic DNA. Translation: AAB39281.1.
AY558097 Genomic DNA. Translation: AAS56423.1.
BK006943 Genomic DNA. Translation: DAA08842.1.
PIRS57074.
RefSeqNP_012589.1. NM_001181713.1.

3D structure databases

ProteinModelPortalP46973.
SMRP46973. Positions 1-45.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid33810. 15 interactions.
DIPDIP-4241N.
IntActP46973. 1 interaction.
MINTMINT-511259.
STRING4932.YJR055W.

Proteomic databases

PaxDbP46973.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYJR055W; YJR055W; YJR055W.
GeneID853516.
KEGGsce:YJR055W.

Organism-specific databases

CYGDYJR055w.
SGDS000003816. HIT1.

Phylogenomic databases

eggNOGNOG40084.
HOGENOMHOG000246653.
OMAACYKNEE.
OrthoDBEOG7J18BW.

Enzyme and pathway databases

BioCycYEAST:G3O-31689-MONOMER.

Gene expression databases

GenevestigatorP46973.

Family and domain databases

InterProIPR007529. Znf_HIT.
[Graphical view]
PfamPF04438. zf-HIT. 1 hit.
[Graphical view]
PROSITEPS51083. ZF_HIT. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio974187.

Entry information

Entry nameHIT1_YEAST
AccessionPrimary (citable) accession number: P46973
Secondary accession number(s): D6VWM6
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: February 19, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome X

Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families