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Protein

Protein HIT1

Gene

HIT1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Miscellaneous

Present with 2730 molecules/cell in log phase SD medium.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri8 – 49HIT-typePROSITE-ProRule annotationAdd BLAST42

GO - Molecular functioni

GO - Biological processi

  • box C/D snoRNP assembly Source: SGD
  • maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Source: SGD

Keywordsi

LigandMetal-binding, Zinc

Enzyme and pathway databases

BioCyciYEAST:G3O-31689-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein HIT1
Gene namesi
Name:HIT1
Ordered Locus Names:YJR055W
ORF Names:J1705
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome X

Organism-specific databases

EuPathDBiFungiDB:YJR055W.
SGDiS000003816. HIT1.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001735561 – 164Protein HIT1Add BLAST164

Proteomic databases

MaxQBiP46973.
PRIDEiP46973.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
RSA1Q089328EBI-8359,EBI-16186

Protein-protein interaction databases

BioGridi33810. 58 interactors.
DIPiDIP-4241N.
IntActiP46973. 4 interactors.
MINTiMINT-511259.
STRINGi4932.YJR055W.

Structurei

Secondary structure

1164
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Turni9 – 11Combined sources3
Beta strandi13 – 15Combined sources3
Turni21 – 23Combined sources3
Beta strandi26 – 29Combined sources4
Helixi30 – 33Combined sources4
Beta strandi36 – 39Combined sources4
Helixi77 – 84Combined sources8
Helixi87 – 92Combined sources6
Helixi96 – 110Combined sources15
Beta strandi119 – 122Combined sources4
Helixi123 – 134Combined sources12
Turni135 – 137Combined sources3
Helixi146 – 160Combined sources15

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2MJFNMR-B70-164[»]
2N95NMR-A1-46[»]
ProteinModelPortaliP46973.
SMRiP46973.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri8 – 49HIT-typePROSITE-ProRule annotationAdd BLAST42

Keywords - Domaini

Zinc-finger

Phylogenomic databases

HOGENOMiHOG000246653.
InParanoidiP46973.
OMAiYGGIHYN.
OrthoDBiEOG092C5Y8T.

Family and domain databases

InterProiView protein in InterPro
IPR007529. Znf_HIT.
PfamiView protein in Pfam
PF04438. zf-HIT. 1 hit.
PROSITEiView protein in PROSITE
PS51083. ZF_HIT. 1 hit.

Sequencei

Sequence statusi: Complete.

P46973-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVSSAVKCGI CRGVDGKYKC PKCGVRYCSL KCYKDAAKHV HKESEQPRAG
60 70 80 90 100
TEANVEVVNN DKIINSSLAM NKTLKTKAFD DIYQNSAELQ ELLKYNTVKF
110 120 130 140 150
HLAKVYRILS STVNDGSSGK MNSDLQKELA VNYLNTLRYG GIHYNEAIEE
160
FCQILLDKLN AVKK
Length:164
Mass (Da):18,376
Last modified:November 1, 1995 - v1
Checksum:iEAC6ABB5457F87AA
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti36 – 37AA → RR in BAA01878 (PubMed:1325386).Curated2

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D11103 Genomic DNA. Translation: BAA01878.1.
Z49555 Genomic DNA. Translation: CAA89583.1.
L47993 Genomic DNA. Translation: AAB39281.1.
AY558097 Genomic DNA. Translation: AAS56423.1.
BK006943 Genomic DNA. Translation: DAA08842.1.
PIRiS57074.
RefSeqiNP_012589.1. NM_001181713.1.

Genome annotation databases

EnsemblFungiiYJR055W; YJR055W; YJR055W.
GeneIDi853516.
KEGGisce:YJR055W.

Similar proteinsi

Entry informationi

Entry nameiHIT1_YEAST
AccessioniPrimary (citable) accession number: P46973
Secondary accession number(s): D6VWM6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: October 25, 2017
This is version 115 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome X
    Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names