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P46956

- PHO86_YEAST

UniProt

P46956 - PHO86_YEAST

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Protein

Inorganic phosphate transporter PHO86

Gene
PHO86, YJL117W, J0744
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at protein leveli

Functioni

Involved in the uptake of inorganic phosphate.

GO - Molecular functioni

  1. protein binding Source: IntAct
  2. unfolded protein binding Source: SGD

GO - Biological processi

  1. ER to Golgi vesicle-mediated transport Source: SGD
  2. phosphate ion transport Source: UniProtKB-KW
  3. protein folding Source: SGD
  4. regulation of phosphate transport Source: SGD
Complete GO annotation...

Keywords - Biological processi

Phosphate transport, Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-31571-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Inorganic phosphate transporter PHO86
Gene namesi
Name:PHO86
Ordered Locus Names:YJL117W
ORF Names:J0744
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome X

Organism-specific databases

CYGDiYJL117w.
SGDiS000003653. PHO86.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 7070Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei71 – 9121Helical; Reviewed predictionAdd
BLAST
Topological domaini92 – 11726Extracellular Reviewed predictionAdd
BLAST
Transmembranei118 – 13821Helical; Reviewed predictionAdd
BLAST
Topological domaini139 – 311173Cytoplasmic Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. endoplasmic reticulum Source: SGD
  2. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 311311Inorganic phosphate transporter PHO86PRO_0000058404Add
BLAST

Proteomic databases

MaxQBiP46956.
PaxDbiP46956.
PeptideAtlasiP46956.

Expressioni

Gene expression databases

GenevestigatoriP46956.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
YMR134WP402073EBI-13337,EBI-27272

Protein-protein interaction databases

BioGridi33637. 138 interactions.
DIPiDIP-2769N.
IntActiP46956. 41 interactions.
MINTiMINT-521701.
STRINGi4932.YJL117W.

Structurei

3D structure databases

ProteinModelPortaliP46956.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG47096.
HOGENOMiHOG000000832.
OMAiYRETPIA.
OrthoDBiEOG7V76K0.

Family and domain databases

InterProiIPR024297. Pho86.
[Graphical view]
PfamiPF11124. Pho86. 1 hit.
[Graphical view]
ProDomiPD130611. PD130611. 1 hit.
[Graphical view] [Entries sharing at least one domain]

Sequencei

Sequence statusi: Complete.

P46956-1 [UniParc]FASTAAdd to Basket

« Hide

MAVQQRKKKE GRKSDKNAPS VPQVDASLDK PLDIDAPPTI YSVNLKPEYG    50
TAALNLSADF IRQEQALANK YLFFHPVILV VLTIGLLIYL TPRIVFPIRN 100
TGSVAGWFYQ LARINKKVVL SGLVFTAIGA SFLFTLLSRV SDSYFKSKIN 150
QLVGSKGEKV FGINLNDLVA RHETKDPVVN NTHIIVYRET PIALISLAPN 200
MTLSTDENLV MSVTTVGCRR VYVKSGIIED LIDWAMLHSK NIRSSGKYGE 250
TMKLLIDVYS FDSTLKEILK KKGFTYIQSI RVSENRLLGG LFGVKKELWG 300
LQFHFKAEHK D 311
Length:311
Mass (Da):34,882
Last modified:November 1, 1995 - v1
Checksum:i1CB19C9184BF1C48
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti8 – 81K → R in AAS56203. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D63817 Genomic DNA. Translation: BAA09885.1.
Z49392 Genomic DNA. Translation: CAA89412.1.
AY557877 Genomic DNA. Translation: AAS56203.1.
BK006943 Genomic DNA. Translation: DAA08683.1.
PIRiS56898.
RefSeqiNP_012418.1. NM_001181550.1.

Genome annotation databases

EnsemblFungiiYJL117W; YJL117W; YJL117W.
GeneIDi853325.
KEGGisce:YJL117W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D63817 Genomic DNA. Translation: BAA09885.1 .
Z49392 Genomic DNA. Translation: CAA89412.1 .
AY557877 Genomic DNA. Translation: AAS56203.1 .
BK006943 Genomic DNA. Translation: DAA08683.1 .
PIRi S56898.
RefSeqi NP_012418.1. NM_001181550.1.

3D structure databases

ProteinModelPortali P46956.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 33637. 138 interactions.
DIPi DIP-2769N.
IntActi P46956. 41 interactions.
MINTi MINT-521701.
STRINGi 4932.YJL117W.

Proteomic databases

MaxQBi P46956.
PaxDbi P46956.
PeptideAtlasi P46956.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YJL117W ; YJL117W ; YJL117W .
GeneIDi 853325.
KEGGi sce:YJL117W.

Organism-specific databases

CYGDi YJL117w.
SGDi S000003653. PHO86.

Phylogenomic databases

eggNOGi NOG47096.
HOGENOMi HOG000000832.
OMAi YRETPIA.
OrthoDBi EOG7V76K0.

Enzyme and pathway databases

BioCyci YEAST:G3O-31571-MONOMER.

Miscellaneous databases

NextBioi 973681.

Gene expression databases

Genevestigatori P46956.

Family and domain databases

InterProi IPR024297. Pho86.
[Graphical view ]
Pfami PF11124. Pho86. 1 hit.
[Graphical view ]
ProDomi PD130611. PD130611. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Two new genes, PHO86 and PHO87, involved in inorganic phosphate uptake in Saccharomyces cerevisiae."
    Bun-Ya M., Shikata K., Nakade S., Yompakdee C., Harashima S., Oshima Y.
    Curr. Genet. 29:344-351(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: S288c / GRF88.
  2. "Sequencing analysis of a 40.2 kb fragment of yeast chromosome X reveals 19 open reading frames including URA2 (5' end), TRK1, PBS2, SPT10, GCD14, RPE1, PHO86, NCA3, ASF1, CCT7, GZF3, two tRNA genes, three remnant delta elements and a Ty4 transposon."
    Cziepluch C., Kordes E., Pujol A., Jauniaux J.-C.
    Yeast 12:1471-1474(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 96604 / S288c / FY1679.
  3. "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."
    Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K.
    , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.
    EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  5. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  6. "A global topology map of the Saccharomyces cerevisiae membrane proteome."
    Kim H., Melen K., Oesterberg M., von Heijne G.
    Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: ATCC 208353 / W303-1A.

Entry informationi

Entry nameiPHO86_YEAST
AccessioniPrimary (citable) accession number: P46956
Secondary accession number(s): D6VW67, E9P8T7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: June 11, 2014
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome X
    Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

External Data

Dasty 3

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