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Protein

Inorganic phosphate transporter PHO86

Gene

PHO86

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Involved in the uptake of inorganic phosphate.

GO - Molecular functioni

  • unfolded protein binding Source: SGD

GO - Biological processi

  • ER to Golgi vesicle-mediated transport Source: SGD
  • phosphate ion transport Source: UniProtKB-KW
  • protein folding Source: SGD
  • regulation of phosphate transport Source: SGD
Complete GO annotation...

Keywords - Biological processi

Phosphate transport, Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-31571-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Inorganic phosphate transporter PHO86
Gene namesi
Name:PHO86
Ordered Locus Names:YJL117W
ORF Names:J0744
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311 Componenti: Chromosome X

Organism-specific databases

CYGDiYJL117w.
EuPathDBiFungiDB:YJL117W.
SGDiS000003653. PHO86.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 7070CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei71 – 9121HelicalSequence AnalysisAdd
BLAST
Topological domaini92 – 11726ExtracellularSequence AnalysisAdd
BLAST
Transmembranei118 – 13821HelicalSequence AnalysisAdd
BLAST
Topological domaini139 – 311173CytoplasmicSequence AnalysisAdd
BLAST

GO - Cellular componenti

  • endoplasmic reticulum Source: SGD
  • integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 311311Inorganic phosphate transporter PHO86PRO_0000058404Add
BLAST

Proteomic databases

MaxQBiP46956.
PaxDbiP46956.
PeptideAtlasiP46956.

Expressioni

Gene expression databases

GenevestigatoriP46956.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
YMR134WP402073EBI-13337,EBI-27272

Protein-protein interaction databases

BioGridi33637. 140 interactions.
DIPiDIP-2769N.
IntActiP46956. 41 interactions.
MINTiMINT-521701.
STRINGi4932.YJL117W.

Structurei

3D structure databases

ProteinModelPortaliP46956.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG47096.
HOGENOMiHOG000000832.
InParanoidiP46956.
OMAiYRETPIA.
OrthoDBiEOG7V76K0.

Family and domain databases

InterProiIPR024297. Pho86.
[Graphical view]
PfamiPF11124. Pho86. 1 hit.
[Graphical view]
ProDomiPD130611. PD130611. 1 hit.
[Graphical view] [Entries sharing at least one domain]

Sequencei

Sequence statusi: Complete.

P46956-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVQQRKKKE GRKSDKNAPS VPQVDASLDK PLDIDAPPTI YSVNLKPEYG
60 70 80 90 100
TAALNLSADF IRQEQALANK YLFFHPVILV VLTIGLLIYL TPRIVFPIRN
110 120 130 140 150
TGSVAGWFYQ LARINKKVVL SGLVFTAIGA SFLFTLLSRV SDSYFKSKIN
160 170 180 190 200
QLVGSKGEKV FGINLNDLVA RHETKDPVVN NTHIIVYRET PIALISLAPN
210 220 230 240 250
MTLSTDENLV MSVTTVGCRR VYVKSGIIED LIDWAMLHSK NIRSSGKYGE
260 270 280 290 300
TMKLLIDVYS FDSTLKEILK KKGFTYIQSI RVSENRLLGG LFGVKKELWG
310
LQFHFKAEHK D
Length:311
Mass (Da):34,882
Last modified:November 1, 1995 - v1
Checksum:i1CB19C9184BF1C48
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti8 – 81K → R in AAS56203 (PubMed:17322287).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D63817 Genomic DNA. Translation: BAA09885.1.
Z49392 Genomic DNA. Translation: CAA89412.1.
AY557877 Genomic DNA. Translation: AAS56203.1.
BK006943 Genomic DNA. Translation: DAA08683.1.
PIRiS56898.
RefSeqiNP_012418.1. NM_001181550.1.

Genome annotation databases

EnsemblFungiiYJL117W; YJL117W; YJL117W.
GeneIDi853325.
KEGGisce:YJL117W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D63817 Genomic DNA. Translation: BAA09885.1.
Z49392 Genomic DNA. Translation: CAA89412.1.
AY557877 Genomic DNA. Translation: AAS56203.1.
BK006943 Genomic DNA. Translation: DAA08683.1.
PIRiS56898.
RefSeqiNP_012418.1. NM_001181550.1.

3D structure databases

ProteinModelPortaliP46956.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi33637. 140 interactions.
DIPiDIP-2769N.
IntActiP46956. 41 interactions.
MINTiMINT-521701.
STRINGi4932.YJL117W.

Proteomic databases

MaxQBiP46956.
PaxDbiP46956.
PeptideAtlasiP46956.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYJL117W; YJL117W; YJL117W.
GeneIDi853325.
KEGGisce:YJL117W.

Organism-specific databases

CYGDiYJL117w.
EuPathDBiFungiDB:YJL117W.
SGDiS000003653. PHO86.

Phylogenomic databases

eggNOGiNOG47096.
HOGENOMiHOG000000832.
InParanoidiP46956.
OMAiYRETPIA.
OrthoDBiEOG7V76K0.

Enzyme and pathway databases

BioCyciYEAST:G3O-31571-MONOMER.

Miscellaneous databases

NextBioi973681.
PROiP46956.

Gene expression databases

GenevestigatoriP46956.

Family and domain databases

InterProiIPR024297. Pho86.
[Graphical view]
PfamiPF11124. Pho86. 1 hit.
[Graphical view]
ProDomiPD130611. PD130611. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Two new genes, PHO86 and PHO87, involved in inorganic phosphate uptake in Saccharomyces cerevisiae."
    Bun-Ya M., Shikata K., Nakade S., Yompakdee C., Harashima S., Oshima Y.
    Curr. Genet. 29:344-351(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: S288c / GRF88.
  2. "Sequencing analysis of a 40.2 kb fragment of yeast chromosome X reveals 19 open reading frames including URA2 (5' end), TRK1, PBS2, SPT10, GCD14, RPE1, PHO86, NCA3, ASF1, CCT7, GZF3, two tRNA genes, three remnant delta elements and a Ty4 transposon."
    Cziepluch C., Kordes E., Pujol A., Jauniaux J.-C.
    Yeast 12:1471-1474(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 96604 / S288c / FY1679.
  3. "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."
    Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K.
    , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.
    EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  5. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  6. "A global topology map of the Saccharomyces cerevisiae membrane proteome."
    Kim H., Melen K., Oesterberg M., von Heijne G.
    Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: ATCC 208353 / W303-1A.

Entry informationi

Entry nameiPHO86_YEAST
AccessioniPrimary (citable) accession number: P46956
Secondary accession number(s): D6VW67, E9P8T7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: May 27, 2015
This is version 106 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome X
    Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.