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P46956

- PHO86_YEAST

UniProt

P46956 - PHO86_YEAST

Protein

Inorganic phosphate transporter PHO86

Gene

PHO86

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 101 (01 Oct 2014)
      Sequence version 1 (01 Nov 1995)
      Previous versions | rss
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    Functioni

    Involved in the uptake of inorganic phosphate.

    GO - Molecular functioni

    1. protein binding Source: IntAct
    2. unfolded protein binding Source: SGD

    GO - Biological processi

    1. ER to Golgi vesicle-mediated transport Source: SGD
    2. phosphate ion transport Source: UniProtKB-KW
    3. protein folding Source: SGD
    4. regulation of phosphate transport Source: SGD

    Keywords - Biological processi

    Phosphate transport, Transport

    Enzyme and pathway databases

    BioCyciYEAST:G3O-31571-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Inorganic phosphate transporter PHO86
    Gene namesi
    Name:PHO86
    Ordered Locus Names:YJL117W
    ORF Names:J0744
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome X

    Organism-specific databases

    CYGDiYJL117w.
    SGDiS000003653. PHO86.

    Subcellular locationi

    GO - Cellular componenti

    1. endoplasmic reticulum Source: SGD
    2. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 311311Inorganic phosphate transporter PHO86PRO_0000058404Add
    BLAST

    Proteomic databases

    MaxQBiP46956.
    PaxDbiP46956.
    PeptideAtlasiP46956.

    Expressioni

    Gene expression databases

    GenevestigatoriP46956.

    Interactioni

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    YMR134WP402073EBI-13337,EBI-27272

    Protein-protein interaction databases

    BioGridi33637. 138 interactions.
    DIPiDIP-2769N.
    IntActiP46956. 41 interactions.
    MINTiMINT-521701.
    STRINGi4932.YJL117W.

    Structurei

    3D structure databases

    ProteinModelPortaliP46956.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 7070CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini92 – 11726ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini139 – 311173CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei71 – 9121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei118 – 13821HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG47096.
    HOGENOMiHOG000000832.
    OMAiYRETPIA.
    OrthoDBiEOG7V76K0.

    Family and domain databases

    InterProiIPR024297. Pho86.
    [Graphical view]
    PfamiPF11124. Pho86. 1 hit.
    [Graphical view]
    ProDomiPD130611. PD130611. 1 hit.
    [Graphical view] [Entries sharing at least one domain]

    Sequencei

    Sequence statusi: Complete.

    P46956-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAVQQRKKKE GRKSDKNAPS VPQVDASLDK PLDIDAPPTI YSVNLKPEYG    50
    TAALNLSADF IRQEQALANK YLFFHPVILV VLTIGLLIYL TPRIVFPIRN 100
    TGSVAGWFYQ LARINKKVVL SGLVFTAIGA SFLFTLLSRV SDSYFKSKIN 150
    QLVGSKGEKV FGINLNDLVA RHETKDPVVN NTHIIVYRET PIALISLAPN 200
    MTLSTDENLV MSVTTVGCRR VYVKSGIIED LIDWAMLHSK NIRSSGKYGE 250
    TMKLLIDVYS FDSTLKEILK KKGFTYIQSI RVSENRLLGG LFGVKKELWG 300
    LQFHFKAEHK D 311
    Length:311
    Mass (Da):34,882
    Last modified:November 1, 1995 - v1
    Checksum:i1CB19C9184BF1C48
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti8 – 81K → R in AAS56203. (PubMed:17322287)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D63817 Genomic DNA. Translation: BAA09885.1.
    Z49392 Genomic DNA. Translation: CAA89412.1.
    AY557877 Genomic DNA. Translation: AAS56203.1.
    BK006943 Genomic DNA. Translation: DAA08683.1.
    PIRiS56898.
    RefSeqiNP_012418.1. NM_001181550.1.

    Genome annotation databases

    EnsemblFungiiYJL117W; YJL117W; YJL117W.
    GeneIDi853325.
    KEGGisce:YJL117W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D63817 Genomic DNA. Translation: BAA09885.1 .
    Z49392 Genomic DNA. Translation: CAA89412.1 .
    AY557877 Genomic DNA. Translation: AAS56203.1 .
    BK006943 Genomic DNA. Translation: DAA08683.1 .
    PIRi S56898.
    RefSeqi NP_012418.1. NM_001181550.1.

    3D structure databases

    ProteinModelPortali P46956.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 33637. 138 interactions.
    DIPi DIP-2769N.
    IntActi P46956. 41 interactions.
    MINTi MINT-521701.
    STRINGi 4932.YJL117W.

    Proteomic databases

    MaxQBi P46956.
    PaxDbi P46956.
    PeptideAtlasi P46956.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YJL117W ; YJL117W ; YJL117W .
    GeneIDi 853325.
    KEGGi sce:YJL117W.

    Organism-specific databases

    CYGDi YJL117w.
    SGDi S000003653. PHO86.

    Phylogenomic databases

    eggNOGi NOG47096.
    HOGENOMi HOG000000832.
    OMAi YRETPIA.
    OrthoDBi EOG7V76K0.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-31571-MONOMER.

    Miscellaneous databases

    NextBioi 973681.

    Gene expression databases

    Genevestigatori P46956.

    Family and domain databases

    InterProi IPR024297. Pho86.
    [Graphical view ]
    Pfami PF11124. Pho86. 1 hit.
    [Graphical view ]
    ProDomi PD130611. PD130611. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    ProtoNeti Search...

    Publicationsi

    1. "Two new genes, PHO86 and PHO87, involved in inorganic phosphate uptake in Saccharomyces cerevisiae."
      Bun-Ya M., Shikata K., Nakade S., Yompakdee C., Harashima S., Oshima Y.
      Curr. Genet. 29:344-351(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: S288c / GRF88.
    2. "Sequencing analysis of a 40.2 kb fragment of yeast chromosome X reveals 19 open reading frames including URA2 (5' end), TRK1, PBS2, SPT10, GCD14, RPE1, PHO86, NCA3, ASF1, CCT7, GZF3, two tRNA genes, three remnant delta elements and a Ty4 transposon."
      Cziepluch C., Kordes E., Pujol A., Jauniaux J.-C.
      Yeast 12:1471-1474(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 96604 / S288c / FY1679.
    3. "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."
      Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K.
      , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.
      EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    4. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    5. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    6. "A global topology map of the Saccharomyces cerevisiae membrane proteome."
      Kim H., Melen K., Oesterberg M., von Heijne G.
      Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
      Strain: ATCC 208353 / W303-1A.

    Entry informationi

    Entry nameiPHO86_YEAST
    AccessioniPrimary (citable) accession number: P46956
    Secondary accession number(s): D6VW67, E9P8T7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: November 1, 1995
    Last modified: October 1, 2014
    This is version 101 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    2. Yeast chromosome X
      Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

    External Data

    Dasty 3