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P46956 (PHO86_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 100. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Inorganic phosphate transporter PHO86
Gene names
Name:PHO86
Ordered Locus Names:YJL117W
ORF Names:J0744
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length311 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Involved in the uptake of inorganic phosphate.

Subcellular location

Membrane; Multi-pass membrane protein Potential.

Binary interactions

With

Entry

#Exp.

IntAct

Notes

YMR134WP402073EBI-13337,EBI-27272

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 311311Inorganic phosphate transporter PHO86
PRO_0000058404

Regions

Topological domain1 – 7070Cytoplasmic Potential
Transmembrane71 – 9121Helical; Potential
Topological domain92 – 11726Extracellular Potential
Transmembrane118 – 13821Helical; Potential
Topological domain139 – 311173Cytoplasmic Potential

Experimental info

Sequence conflict81K → R in AAS56203. Ref.5

Sequences

Sequence LengthMass (Da)Tools
P46956 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: 1CB19C9184BF1C48

FASTA31134,882
        10         20         30         40         50         60 
MAVQQRKKKE GRKSDKNAPS VPQVDASLDK PLDIDAPPTI YSVNLKPEYG TAALNLSADF 

        70         80         90        100        110        120 
IRQEQALANK YLFFHPVILV VLTIGLLIYL TPRIVFPIRN TGSVAGWFYQ LARINKKVVL 

       130        140        150        160        170        180 
SGLVFTAIGA SFLFTLLSRV SDSYFKSKIN QLVGSKGEKV FGINLNDLVA RHETKDPVVN 

       190        200        210        220        230        240 
NTHIIVYRET PIALISLAPN MTLSTDENLV MSVTTVGCRR VYVKSGIIED LIDWAMLHSK 

       250        260        270        280        290        300 
NIRSSGKYGE TMKLLIDVYS FDSTLKEILK KKGFTYIQSI RVSENRLLGG LFGVKKELWG 

       310 
LQFHFKAEHK D 

« Hide

References

« Hide 'large scale' references
[1]"Two new genes, PHO86 and PHO87, involved in inorganic phosphate uptake in Saccharomyces cerevisiae."
Bun-Ya M., Shikata K., Nakade S., Yompakdee C., Harashima S., Oshima Y.
Curr. Genet. 29:344-351(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: S288c / GRF88.
[2]"Sequencing analysis of a 40.2 kb fragment of yeast chromosome X reveals 19 open reading frames including URA2 (5' end), TRK1, PBS2, SPT10, GCD14, RPE1, PHO86, NCA3, ASF1, CCT7, GZF3, two tRNA genes, three remnant delta elements and a Ty4 transposon."
Cziepluch C., Kordes E., Pujol A., Jauniaux J.-C.
Yeast 12:1471-1474(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 96604 / S288c / FY1679.
[3]"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."
Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K. expand/collapse author list , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.
EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[4]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[5]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[6]"A global topology map of the Saccharomyces cerevisiae membrane proteome."
Kim H., Melen K., Oesterberg M., von Heijne G.
Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
Strain: ATCC 208353 / W303-1A.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D63817 Genomic DNA. Translation: BAA09885.1.
Z49392 Genomic DNA. Translation: CAA89412.1.
AY557877 Genomic DNA. Translation: AAS56203.1.
BK006943 Genomic DNA. Translation: DAA08683.1.
PIRS56898.
RefSeqNP_012418.1. NM_001181550.1.

3D structure databases

ProteinModelPortalP46956.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid33637. 138 interactions.
DIPDIP-2769N.
IntActP46956. 41 interactions.
MINTMINT-521701.
STRING4932.YJL117W.

Proteomic databases

MaxQBP46956.
PaxDbP46956.
PeptideAtlasP46956.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYJL117W; YJL117W; YJL117W.
GeneID853325.
KEGGsce:YJL117W.

Organism-specific databases

CYGDYJL117w.
SGDS000003653. PHO86.

Phylogenomic databases

eggNOGNOG47096.
HOGENOMHOG000000832.
OMAYRETPIA.
OrthoDBEOG7V76K0.

Enzyme and pathway databases

BioCycYEAST:G3O-31571-MONOMER.

Gene expression databases

GenevestigatorP46956.

Family and domain databases

InterProIPR024297. Pho86.
[Graphical view]
PfamPF11124. Pho86. 1 hit.
[Graphical view]
ProDomPD130611. PD130611. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetSearch...

Other

NextBio973681.

Entry information

Entry namePHO86_YEAST
AccessionPrimary (citable) accession number: P46956
Secondary accession number(s): D6VW67, E9P8T7
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: June 11, 2014
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome X

Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD