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Protein

Protein SIP4

Gene

SIP4

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Protein predictedi

Functioni

Interacts with the SNF1 protein kinase.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi46 – 73Zn(2)-C6 fungal-typePROSITE-ProRule annotationAdd BLAST28

GO - Molecular functioni

GO - Biological processi

  • negative regulation of invasive growth in response to glucose limitation Source: SGD
  • positive regulation of gluconeogenesis Source: SGD
  • positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter Source: SGD
  • positive regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source Source: SGD

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

BioCyciYEAST:G3O-31544-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Protein SIP4
Gene namesi
Name:SIP4
Ordered Locus Names:YJL089W
ORF Names:J0922
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome X

Organism-specific databases

EuPathDBiFungiDB:YJL089W
SGDiS000003625 SIP4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001149791 – 829Protein SIP4Add BLAST829

Proteomic databases

PaxDbiP46954
PRIDEiP46954

Interactioni

Protein-protein interaction databases

BioGridi33668, 136 interactors
DIPiDIP-840N
STRINGi4932.YJL089W

Structurei

3D structure databases

ProteinModelPortaliP46954
SMRiP46954
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00530000068569
InParanoidiP46954
OMAiPRGYTEM
OrthoDBiEOG092C0Z0C

Family and domain databases

CDDicd00067 GAL4, 1 hit
Gene3Di4.10.240.10, 1 hit
InterProiView protein in InterPro
IPR001138 Zn2-C6_fun-type_DNA-bd
IPR036864 Zn2-C6_fun-type_DNA-bd_sf
PfamiView protein in Pfam
PF00172 Zn_clus, 1 hit
SMARTiView protein in SMART
SM00066 GAL4, 1 hit
SUPFAMiSSF57701 SSF57701, 1 hit
PROSITEiView protein in PROSITE
PS00463 ZN2_CY6_FUNGAL_1, 1 hit
PS50048 ZN2_CY6_FUNGAL_2, 1 hit

Sequencei

Sequence statusi: Complete.

P46954-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKRKYGRSY SLDDTDSCSN KVLIVPTGQS SSNAITDFSV RKAHACDRCR
60 70 80 90 100
LKKIKCDGLK PNCSNCAKID FPCKTSDKLS RRGLPKGYTE LLEKEVVRLT
110 120 130 140 150
NMNASSSANA NSNLPFINDT FYCFDNYNTQ SENQRFLGHL TWNILTNTFP
160 170 180 190 200
TQKAVVFTDD RNNIDLQLQL LTNFLNLNGD FNHLPNFLLL KYDYNLQFLK
210 220 230 240 250
NLLSVIIKDF FKRQNSLLLL LYPTNLWKNL LLDKINSTAM TGEPITLLAL
260 270 280 290 300
LYIIQFTWSC FDDFKLFKVT KLIVSLTTNS KLDLKVLQLV NLSIFYFMGA
310 320 330 340 350
SVDSCKSKSS LTEHSNVNSV IWTNDLLNLN FTNILNMGLY INPKNLIPIS
360 370 380 390 400
GNNNNNKSNE EDDRIVTFWC FQFLSSWWSL IQGLPKSNFL TEEFQPKSIS
410 420 430 440 450
VLEIPRLKPF EILLNFIIYS LDGCNLLNIS SLNVSDPNFQ FFQNELESFK
460 470 480 490 500
KNLLLWNLYH NLSDHDNFRF LTSSSNKKLT TNLLLKNLTG LNHKLNQPDF
510 520 530 540 550
VEIQLTLFYL SLKLMTLKEG DQDLKKEDIS LEILSLYFLI LTDDSNNDDN
560 570 580 590 600
QQLQPQQLNL YHFTPFNSID IIDLCLNNLN NWSLSLKYES GQNQPHSSKI
610 620 630 640 650
KFEKFQNFLN HWCPIWYYDE FSTNPFLQIL KINFKLLPFE TIHYSQEEQR
660 670 680 690 700
LLISLNKLRY LDAVSSFNSS SVKSNFASKV NTQLNLLQHS SSNSNFLDAS
710 720 730 740 750
PYDFNKIFMN NFENYDYETD EGYAEDDDEE DSDSDNSLPL EIPFKKSKNK
760 770 780 790 800
CKNRNKELSQ RLSLFENRDS NSVDFNTDTN LNLNPDSPSV TSSKKKYLDH
810 820
IILDNRDIVS NHDSSKQKFK IQNILNSTF
Length:829
Mass (Da):96,005
Last modified:November 1, 1995 - v1
Checksum:i5B1185166E55E3F7
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti656N → T in AAB04119 (Ref. 1) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U17643 Genomic DNA Translation: AAB04119.1
X83502 Genomic DNA Translation: CAA58479.1
Z49364 Genomic DNA Translation: CAA89382.1
BK006943 Genomic DNA Translation: DAA08711.1
PIRiS50246
RefSeqiNP_012446.1, NM_001181522.1

Genome annotation databases

EnsemblFungiiYJL089W; YJL089W; YJL089W
GeneIDi853356
KEGGisce:YJL089W

Similar proteinsi

Entry informationi

Entry nameiSIP4_YEAST
AccessioniPrimary (citable) accession number: P46954
Secondary accession number(s): D6VW95
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: May 23, 2018
This is version 125 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome X
    Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

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