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Protein

Nitrosoguanidine resistance protein SNG1

Gene

SNG1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May function as a N-methyl-N'nitro-N-nitrosoguanidine (MNNG) export permease.

GO - Biological processi

  • nucleobase-containing compound transport Source: SGD
  • regulation of fungal-type cell wall organization Source: SGD
  • regulation of phospholipid translocation Source: SGD

Enzyme and pathway databases

BioCyciYEAST:G3O-30883-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Nitrosoguanidine resistance protein SNG1
Gene namesi
Name:SNG1
Ordered Locus Names:YGR197C
ORF Names:G7591
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VII

Organism-specific databases

EuPathDBiFungiDB:YGR197C
SGDiS000003429 SNG1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei109 – 129HelicalSequence analysisAdd BLAST21
Transmembranei159 – 179HelicalSequence analysisAdd BLAST21
Transmembranei318 – 338HelicalSequence analysisAdd BLAST21
Transmembranei363 – 383HelicalSequence analysisAdd BLAST21
Transmembranei394 – 414HelicalSequence analysisAdd BLAST21
Transmembranei418 – 438HelicalSequence analysisAdd BLAST21
Transmembranei457 – 477HelicalSequence analysisAdd BLAST21
Transmembranei488 – 508HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000720071 – 547Nitrosoguanidine resistance protein SNG1Add BLAST547

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei91PhosphothreonineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP46950
PRIDEiP46950

PTM databases

iPTMnetiP46950

Expressioni

Inductioni

Transcriptionally regulated by PDR8.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi33450, 230 interactors
DIPiDIP-8148N
IntActiP46950, 1 interactor
STRINGi4932.YGR197C

Structurei

3D structure databases

ProteinModelPortaliP46950
SMRiP46950
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

To yeast YJR015W.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00390000015455
HOGENOMiHOG000141871
InParanoidiP46950
OMAiYYSQARN
OrthoDBiEOG092C3NIW

Family and domain databases

InterProiView protein in InterPro
IPR022703 DUF3533
PfamiView protein in Pfam
PF12051 DUF3533, 1 hit

Sequencei

Sequence statusi: Complete.

P46950-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKSVGDEES QYIEDPSFAA AAAFTGGRDG VSYSNQRFAE GSGHSSDLAK
60 70 80 90 100
SLEDYRPPDE KPSSLSSVGE GGANEEEKGG NDGGPLARIQ TGLFSPRLRN
110 120 130 140 150
HRKKILSKFV LNNFFIACVC VSLISIYWGA CYGTDRYFFK VKNIVVLQDA
160 170 180 190 200
PSNTSVQSIS AIIPSLLASV PGTWHIYNAT SFHRKFGTTN STEIDRKIVD
210 220 230 240 250
LIYDERYWLA LNVKPNATDT LYNSLISQDA NSEFNSSIFF ESVFESGRDP
260 270 280 290 300
SSVKSTILPL MQQLEVRLQK YYVKEYLPSL MSNITSNDRD LNINMENWAI
310 320 330 340 350
AGQLLFTYND YRPFADRILM APLQVGLIYC ILLTVLQLSL YGKLHGEMAR
360 370 380 390 400
VLKPKHILIY RLLISWATYF LLSIGFCTVS AIFRIDFTPA FGRGGFVVYW
410 420 430 440 450
MSTWLVMMAV GGANENVLSL VIAYCPPYLS IWLMTWIILN ISASFYPMVL
460 470 480 490 500
NNEFYRYGYI MPIHNAVDIY KVIFLNLTKR KMGRNYGILV AWVALNTSLM
510 520 530 540
PFCMKFAGKK MQKNAMQAAE AAVAAATQRA SRPAEANTDK NNNPPGN
Length:547
Mass (Da):61,293
Last modified:November 1, 1995 - v1
Checksum:iD4421BA2DED55420
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti117A → V in CAA52881 (PubMed:7753113).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X74920 Genomic DNA Translation: CAA52881.1
X82775 Genomic DNA Translation: CAA58016.1
Z72982 Genomic DNA Translation: CAA97224.1
BK006941 Genomic DNA Translation: DAA08290.1
PIRiS53920
RefSeqiNP_011713.1, NM_001181326.1

Genome annotation databases

EnsemblFungiiYGR197C; YGR197C; YGR197C
GeneIDi853111
KEGGisce:YGR197C

Similar proteinsi

Entry informationi

Entry nameiSNG1_YEAST
AccessioniPrimary (citable) accession number: P46950
Secondary accession number(s): D6VUX9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: March 28, 2018
This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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