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Protein

Glycine betaine transport system permease protein OpuAB

Gene

opuAB

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Involved in a multicomponent binding-protein-dependent transport system for glycine betaine; probably responsible for the translocation of the substrate across the membrane.2 Publications

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Amino-acid transport, Transport

Enzyme and pathway databases

BioCyciBSUB:BSU02990-MONOMER.
RETL1328306-WGS:GSTH-3131-MONOMER.
RETL1328306-WGS:GSTH-4754-MONOMER.
RETL1328306-WGS:GSTH-4755-MONOMER.

Protein family/group databases

TCDBi3.A.1.12.2. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycine betaine transport system permease protein OpuAB
Gene namesi
Name:opuAB
Ordered Locus Names:BSU02990
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 1818ExtracellularSequence analysisAdd
BLAST
Transmembranei19 – 3921HelicalPROSITE-ProRule annotationAdd
BLAST
Topological domaini40 – 445CytoplasmicSequence analysis
Transmembranei45 – 6521HelicalPROSITE-ProRule annotationAdd
BLAST
Topological domaini66 – 694ExtracellularSequence analysis
Transmembranei70 – 9021HelicalPROSITE-ProRule annotationAdd
BLAST
Topological domaini91 – 933CytoplasmicSequence analysis
Transmembranei94 – 11421HelicalPROSITE-ProRule annotationAdd
BLAST
Topological domaini115 – 13723ExtracellularSequence analysisAdd
BLAST
Transmembranei138 – 15821HelicalPROSITE-ProRule annotationAdd
BLAST
Topological domaini159 – 21557CytoplasmicSequence analysisAdd
BLAST
Transmembranei216 – 23621HelicalPROSITE-ProRule annotationAdd
BLAST
Topological domaini237 – 2426ExtracellularSequence analysis
Transmembranei243 – 26321HelicalPROSITE-ProRule annotationAdd
BLAST
Topological domaini264 – 28219CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 282282Glycine betaine transport system permease protein OpuABPRO_0000060153Add
BLAST

Proteomic databases

PaxDbiP46921.

Interactioni

Subunit structurei

The complex is composed of two ATP-binding proteins (OpuAA), two transmembrane proteins (OpuAB) and a solute-binding protein (OpuAC).1 Publication

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100001643.

Structurei

3D structure databases

ProteinModelPortaliP46921.
SMRiP46921. Positions 86-269.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini90 – 269180ABC transmembrane type-1PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 ABC transmembrane type-1 domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4107SQ8. Bacteria.
COG4176. LUCA.
HOGENOMiHOG000279300.
InParanoidiP46921.
KOiK02001.
OMAiMWALMAF.
PhylomeDBiP46921.

Family and domain databases

CDDicd06261. TM_PBP2. 1 hit.
Gene3Di1.10.3720.10. 1 hit.
InterProiIPR000515. MetI-like.
[Graphical view]
PfamiPF00528. BPD_transp_1. 1 hit.
[Graphical view]
SUPFAMiSSF161098. SSF161098. 1 hit.
PROSITEiPS50928. ABC_TM1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P46921-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDRLPRIPLA DIIDRFVDWI TMTFGGFFDG IANGLAAFVN GIVTGLGFIP
60 70 80 90 100
SILLTIIFAA LAWWISTRGI ALFTLIGFLL IDYLGYWDPM LQTLALVLTS
110 120 130 140 150
VIISIVVGVP IGIWASQKET VRRIVTPILD LMQTMPAFVY LLPAIFFFNI
160 170 180 190 200
GVVPGVVASV IFAMPPTIRM TVLGIKQVPA DLIEATEAFG STTAQRLFKV
210 220 230 240 250
QLPLATKTIL AGINQSIMLA LSMVVIAAMV GAPGLGSEVY SAVTQLKTGV
260 270 280
GVEAGIAIVI VAITLDRITQ NIKVKKKSRG NA
Length:282
Mass (Da):30,247
Last modified:November 1, 1995 - v1
Checksum:iB05FDABD403BDBC1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U17292 Genomic DNA. Translation: AAC43456.1.
D50453 Genomic DNA. Translation: BAA08933.1.
AL009126 Genomic DNA. Translation: CAB12093.1.
PIRiI40536.
RefSeqiNP_388181.1. NC_000964.3.
WP_003234703.1. NZ_JNCM01000030.1.

Genome annotation databases

EnsemblBacteriaiCAB12093; CAB12093; BSU02990.
GeneIDi938360.
KEGGibsu:BSU02990.
PATRICi18972157. VBIBacSub10457_0307.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U17292 Genomic DNA. Translation: AAC43456.1.
D50453 Genomic DNA. Translation: BAA08933.1.
AL009126 Genomic DNA. Translation: CAB12093.1.
PIRiI40536.
RefSeqiNP_388181.1. NC_000964.3.
WP_003234703.1. NZ_JNCM01000030.1.

3D structure databases

ProteinModelPortaliP46921.
SMRiP46921. Positions 86-269.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100001643.

Protein family/group databases

TCDBi3.A.1.12.2. the atp-binding cassette (abc) superfamily.

Proteomic databases

PaxDbiP46921.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB12093; CAB12093; BSU02990.
GeneIDi938360.
KEGGibsu:BSU02990.
PATRICi18972157. VBIBacSub10457_0307.

Phylogenomic databases

eggNOGiENOG4107SQ8. Bacteria.
COG4176. LUCA.
HOGENOMiHOG000279300.
InParanoidiP46921.
KOiK02001.
OMAiMWALMAF.
PhylomeDBiP46921.

Enzyme and pathway databases

BioCyciBSUB:BSU02990-MONOMER.
RETL1328306-WGS:GSTH-3131-MONOMER.
RETL1328306-WGS:GSTH-4754-MONOMER.
RETL1328306-WGS:GSTH-4755-MONOMER.

Family and domain databases

CDDicd06261. TM_PBP2. 1 hit.
Gene3Di1.10.3720.10. 1 hit.
InterProiIPR000515. MetI-like.
[Graphical view]
PfamiPF00528. BPD_transp_1. 1 hit.
[Graphical view]
SUPFAMiSSF161098. SSF161098. 1 hit.
PROSITEiPS50928. ABC_TM1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiOPUAB_BACSU
AccessioniPrimary (citable) accession number: P46921
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: September 7, 2016
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.