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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBSUB:BSU37330-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligase (EC:6.1.1.19)
Alternative name(s):
Arginyl-tRNA synthetase
Short name:
ArgRS
Gene namesi
Name:argS
Ordered Locus Names:BSU37330
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001515301 – 556Arginine--tRNA ligaseAdd BLAST556

Proteomic databases

PaxDbiP46906
PRIDEiP46906

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

IntActiP46906 1 interactor.
MINTiP46906
STRINGi224308.Bsubs1_010100020176

Structurei

3D structure databases

ProteinModelPortaliP46906
SMRiP46906
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi132 – 142"HIGH" regionAdd BLAST11

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247214
InParanoidiP46906
KOiK01887
OMAiHGMSTRQ
PhylomeDBiP46906

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.701 hit
3.40.50.6201 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

P46906-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIAEQMKDV LKEEIKAAVL KAGLAEESQI PNVVLETPKD KTHGDYSTNM
60 70 80 90 100
AMQLARVAKK APRQIAEEIV AHFDKGKASI EKLDIAGPGF INFYMNNQYL
110 120 130 140 150
TKLIPSVLEA GEAYGETNIG NGERVQVEFV SANPTGDLHL GHARGAAVGD
160 170 180 190 200
SLCNVLSKAG YDVSREYYIN DAGNQINNLA LSVEVRYFEA LGLEKPMPED
210 220 230 240 250
GYRGEDIIAI GKRLAEEYGD RFVNEEESER LAFFREYGLK YELEKLRKDL
260 270 280 290 300
ENFRVPFDVW YSETSLYQNG KIDKALEALR EKGHVYEEDG ATWFRSTTFG
310 320 330 340 350
DDKDRVLIKK DGTYTYLLPD IAYHKDKLDR GFDKLINVWG ADHHGYIPRM
360 370 380 390 400
KAAIEALGYE KGTLEVEIIQ LVHLYKNGEK MKMSKRTGKA VTMRDLIEEV
410 420 430 440 450
GLDAVRYFFA MRSADTHMDF DLDLAVSTSN ENPVYYAQYA HARICSMLRQ
460 470 480 490 500
GEEQGLKPAA DLDFSHIQSE KEYDLLKTIG GFPEAVAEAA EKRIPHRVTN
510 520 530 540 550
YIYDLASALH SFYNAEKVID PENEEKSRAR LALMKATQIT LNNALQLIGV

SAPEKM
Length:556
Mass (Da):62,723
Last modified:July 15, 1998 - v2
Checksum:i0D92ED44E50BCD7F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z97024 Genomic DNA Translation: CAB09703.1
AL009126 Genomic DNA Translation: CAB15761.1
Z49884 Genomic DNA Translation: CAA90040.1
PIRiE69589
RefSeqiNP_391614.1, NC_000964.3
WP_003227570.1, NZ_JNCM01000034.1

Genome annotation databases

EnsemblBacteriaiCAB15761; CAB15761; BSU37330
GeneIDi937054
KEGGibsu:BSU37330
PATRICifig|224308.179.peg.4044

Similar proteinsi

Entry informationi

Entry nameiSYR_BACSU
AccessioniPrimary (citable) accession number: P46906
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: July 15, 1998
Last modified: March 28, 2018
This is version 135 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome