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Protein

Universal stress protein C

Gene

uspC

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Required for resistance to DNA-damaging agents.1 Publication

GO - Molecular functioni

  • protein-containing complex scaffold activity Source: EcoCyc

GO - Biological processi

  • response to salt stress Source: CACAO

Enzyme and pathway databases

BioCyciEcoCyc:G7031-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Universal stress protein C
Gene namesi
Name:uspC
Synonyms:yecG
Ordered Locus Names:b1895, JW1884
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12862 uspC

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001474081 – 142Universal stress protein CAdd BLAST142

Proteomic databases

PaxDbiP46888
PRIDEiP46888

Expressioni

Inductioni

During growth inhibition caused by the exhaustion of any of a variety of nutrients (carbon, nitrogen, phosphate, sulfate, required amino acid) or by the presence of a variety of toxic agents. Positively regulated by guanosine 3',5'-bisphosphate (ppGpp) and by a RecA/FtsK-dependent regulatory pathway.1 Publication

Interactioni

GO - Molecular functioni

  • protein-containing complex scaffold activity Source: EcoCyc

Protein-protein interaction databases

BioGridi4259472, 10 interactors
IntActiP46888, 11 interactors
STRINGi316385.ECDH10B_2036

Structurei

3D structure databases

ProteinModelPortaliP46888
SMRiP46888
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the universal stress protein A family.Curated

Phylogenomic databases

eggNOGiENOG4108VA4 Bacteria
COG0589 LUCA
HOGENOMiHOG000238899
InParanoidiP46888
KOiK14064
OMAiCGNHNQS
PhylomeDBiP46888

Family and domain databases

Gene3Di3.40.50.620, 1 hit
InterProiView protein in InterPro
IPR014729 Rossmann-like_a/b/a_fold
IPR006015 Universal_stress_UspA
IPR006016 UspA
PfamiView protein in Pfam
PF00582 Usp, 1 hit
PIRSFiPIRSF006276 UspA, 1 hit

Sequencei

Sequence statusi: Complete.

P46888-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSYSNILVAV AVTPESQQLL AKAVSIARPV KGHISLITLA SDPEMYNQLA
60 70 80 90 100
APMLEDLRSV MHEETQSFLD KLIQDAGYPV DKTFIAYGEL SEHILEVCHK
110 120 130 140
HHFDLVICGN HNHSFFSRAS CSAKRVIASS EVDVLLVPLT GD
Length:142
Mass (Da):15,633
Last modified:November 1, 1995 - v1
Checksum:i87DFEE19A8EE58FC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U27211 Genomic DNA Translation: AAA68603.1
U00096 Genomic DNA Translation: AAC74965.1
AP009048 Genomic DNA Translation: BAA15716.1
PIRiG64952
RefSeqiNP_416409.1, NC_000913.3
WP_000122416.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC74965; AAC74965; b1895
BAA15716; BAA15716; BAA15716
GeneIDi946404
KEGGiecj:JW1884
eco:b1895
PATRICifig|1411691.4.peg.354

Similar proteinsi

Entry informationi

Entry nameiUSPC_ECOLI
AccessioniPrimary (citable) accession number: P46888
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: April 25, 2018
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

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