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P46882 (AOFN_ASPNG) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Monoamine oxidase N
Short name=MAO-N
EC=1.4.3.4
Gene names
Name:maoN
OrganismAspergillus niger
Taxonomic identifier5061 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › mitosporic Trichocomaceae › Aspergillus

Protein attributes

Sequence length495 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

RCH2NHR' + H2O + O2 = RCHO + R'NH2 + H2O2.

Cofactor

FAD.

Subcellular location

Peroxisome Probable.

Sequence similarities

Belongs to the flavin monoamine oxidase family.

Ontologies

Keywords
   Cellular componentPeroxisome
   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
   Technical term3D-structure
Direct protein sequencing
Gene Ontology (GO)
   Cellular_componentperoxisome

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionoxidoreductase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 495495Monoamine oxidase N
PRO_0000099865

Regions

Motif493 – 4953Microbody targeting signal Potential

Secondary structure

1 ................................................................................................... 495
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P46882 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: 0E614FF09D3C5B3D

FASTA49555,617
        10         20         30         40         50         60 
MTSRDGYQWT PETGLTQGVP SLGVISPPTN IEDTDKDGPW DVIVIGGGYC GLTATRDLTV 

        70         80         90        100        110        120 
AGFKTLLLEA RDRIGGRSWS SNIDGYPYEM GGTWVHWHQS HVWREITRYK MHNALSPSFN 

       130        140        150        160        170        180 
FSRGVNHFQL RTNPTTSTYM THEAEDELLR SALHKFTNVD GTNGRTVLPF PHDMFYVPEF 

       190        200        210        220        230        240 
RKYDEMSYSE RIDQIRDELS LNERSSLEAF ILLCSGGTLE NSSFGEFLHW WAMSGYTYQG 

       250        260        270        280        290        300 
CMDCLISYKF KDGQSAFARR FWEEAAGTGR LGYVFGCPVR SVVNERDAAR VTARDGREFA 

       310        320        330        340        350        360 
AKRLVCTIPL NVLSTIQFSP ALSTERISAM QAGHVNMCTK VHAEVDNKDM RSWTGIAYPF 

       370        380        390        400        410        420 
NKLCYAIGDG TTPAGNTHLV CFGTDANHIQ PDEDVRETLK AVGQLAPGTF GVKRLVFHNW 

       430        440        450        460        470        480 
VKDEFAKGAW FFSRPGMVSE CLQGLREKHR GVVFANSDWA LGWRSFIDGA IEEGTRAARV 

       490 
VLEELGTKRE VKARL

« Hide

References

[1]"Cloning, sequencing and heterologous expression of the monoamine oxidase gene from Aspergillus niger."
Schilling B., Lerch K.
Mol. Gen. Genet. 247:430-438(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 165-175.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		L38858 Genomic DNA. Translation: AAA98490.1.
PIRS55273.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2VVLX-ray2.45A/B/C/D/E/F/G/H1-495[»]
2VVMX-ray1.85A/B1-495[»]
ProteinModelPortalP46882.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

eggNOGCOG1231.

Family and domain databases

InterProIPR002937. Amino_oxidase.
IPR001613. Flavin_amine_oxidase.
[Graphical view]
PfamPF01593. Amino_oxidase. 1 hit.
[Graphical view]
PRINTSPR00757. AMINEOXDASEF.
ProtoNetSearch...

Other

EvolutionaryTraceP46882.

Entry information

Entry nameAOFN_ASPNG
AccessionPrimary (citable) accession number: P46882
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: May 1, 2013
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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