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P46882

- AOFN_ASPNG

UniProt

P46882 - AOFN_ASPNG

Protein

Monoamine oxidase N

Gene

maoN

Organism
Aspergillus niger
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 71 (01 Oct 2014)
      Sequence version 1 (01 Nov 1995)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    RCH2NHR' + H2O + O2 = RCHO + R'NH2 + H2O2.

    Cofactori

    FAD.

    GO - Molecular functioni

    1. oxidoreductase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Ligandi

    FAD, Flavoprotein

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Monoamine oxidase N (EC:1.4.3.4)
    Short name:
    MAO-N
    Gene namesi
    Name:maoN
    OrganismiAspergillus niger
    Taxonomic identifieri5061 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

    Subcellular locationi

    Peroxisome Curated

    GO - Cellular componenti

    1. peroxisome Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Peroxisome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 495495Monoamine oxidase NPRO_0000099865Add
    BLAST

    Structurei

    Secondary structure

    1
    495
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi7 – 104
    Turni11 – 133
    Beta strandi14 – 174
    Beta strandi26 – 294
    Beta strandi40 – 456
    Helixi49 – 6012
    Beta strandi65 – 684
    Beta strandi70 – 756
    Beta strandi80 – 834
    Beta strandi86 – 894
    Helixi100 – 1089
    Beta strandi115 – 1184
    Beta strandi122 – 1243
    Beta strandi127 – 1337
    Beta strandi138 – 1403
    Helixi142 – 15716
    Beta strandi159 – 1624
    Turni163 – 1675
    Helixi180 – 1845
    Helixi188 – 1958
    Helixi196 – 1983
    Helixi201 – 21515
    Turni219 – 2213
    Helixi224 – 23310
    Helixi238 – 2469
    Beta strandi247 – 2504
    Helixi254 – 26613
    Turni267 – 2693
    Beta strandi271 – 2766
    Beta strandi279 – 2846
    Beta strandi286 – 2938
    Beta strandi298 – 3069
    Helixi310 – 3156
    Beta strandi316 – 3205
    Helixi324 – 3329
    Beta strandi339 – 3468
    Helixi348 – 3525
    Beta strandi353 – 3575
    Beta strandi359 – 3624
    Beta strandi365 – 3717
    Beta strandi377 – 3837
    Helixi385 – 3873
    Turni391 – 3933
    Helixi395 – 4039
    Beta strandi412 – 4176
    Turni420 – 4223
    Turni424 – 4263
    Beta strandi427 – 4304
    Helixi437 – 44610
    Beta strandi452 – 4543
    Helixi457 – 4593
    Beta strandi461 – 4633
    Helixi467 – 48519

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2VVLX-ray2.45A/B/C/D/E/F/G/H1-495[»]
    2VVMX-ray1.85A/B1-495[»]
    3ZDNX-ray2.55A/B/C/D1-495[»]
    ProteinModelPortaliP46882.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiP46882.

    Family & Domainsi

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi493 – 4953Microbody targeting signalSequence Analysis

    Sequence similaritiesi

    Belongs to the flavin monoamine oxidase family.Curated

    Phylogenomic databases

    eggNOGiCOG1231.

    Family and domain databases

    InterProiIPR002937. Amino_oxidase.
    IPR001613. Flavin_amine_oxidase.
    [Graphical view]
    PfamiPF01593. Amino_oxidase. 1 hit.
    [Graphical view]
    PRINTSiPR00757. AMINEOXDASEF.

    Sequencei

    Sequence statusi: Complete.

    P46882-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTSRDGYQWT PETGLTQGVP SLGVISPPTN IEDTDKDGPW DVIVIGGGYC    50
    GLTATRDLTV AGFKTLLLEA RDRIGGRSWS SNIDGYPYEM GGTWVHWHQS 100
    HVWREITRYK MHNALSPSFN FSRGVNHFQL RTNPTTSTYM THEAEDELLR 150
    SALHKFTNVD GTNGRTVLPF PHDMFYVPEF RKYDEMSYSE RIDQIRDELS 200
    LNERSSLEAF ILLCSGGTLE NSSFGEFLHW WAMSGYTYQG CMDCLISYKF 250
    KDGQSAFARR FWEEAAGTGR LGYVFGCPVR SVVNERDAAR VTARDGREFA 300
    AKRLVCTIPL NVLSTIQFSP ALSTERISAM QAGHVNMCTK VHAEVDNKDM 350
    RSWTGIAYPF NKLCYAIGDG TTPAGNTHLV CFGTDANHIQ PDEDVRETLK 400
    AVGQLAPGTF GVKRLVFHNW VKDEFAKGAW FFSRPGMVSE CLQGLREKHR 450
    GVVFANSDWA LGWRSFIDGA IEEGTRAARV VLEELGTKRE VKARL 495
    Length:495
    Mass (Da):55,617
    Last modified:November 1, 1995 - v1
    Checksum:i0E614FF09D3C5B3D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L38858 Genomic DNA. Translation: AAA98490.1.
    PIRiS55273.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L38858 Genomic DNA. Translation: AAA98490.1 .
    PIRi S55273.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2VVL X-ray 2.45 A/B/C/D/E/F/G/H 1-495 [» ]
    2VVM X-ray 1.85 A/B 1-495 [» ]
    3ZDN X-ray 2.55 A/B/C/D 1-495 [» ]
    ProteinModelPortali P46882.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    eggNOGi COG1231.

    Miscellaneous databases

    EvolutionaryTracei P46882.

    Family and domain databases

    InterProi IPR002937. Amino_oxidase.
    IPR001613. Flavin_amine_oxidase.
    [Graphical view ]
    Pfami PF01593. Amino_oxidase. 1 hit.
    [Graphical view ]
    PRINTSi PR00757. AMINEOXDASEF.
    ProtoNeti Search...

    Publicationsi

    1. "Cloning, sequencing and heterologous expression of the monoamine oxidase gene from Aspergillus niger."
      Schilling B., Lerch K.
      Mol. Gen. Genet. 247:430-438(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 165-175.

    Entry informationi

    Entry nameiAOFN_ASPNG
    AccessioniPrimary (citable) accession number: P46882
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: November 1, 1995
    Last modified: October 1, 2014
    This is version 71 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Direct protein sequencing

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3