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Protein

Monoamine oxidase N

Gene

maoN

Organism
Aspergillus niger
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

RCH2NHR' + H2O + O2 = RCHO + R'NH2 + H2O2.

Cofactori

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

FAD, Flavoprotein

Enzyme and pathway databases

BRENDAi1.4.3.4. 518.

Names & Taxonomyi

Protein namesi
Recommended name:
Monoamine oxidase N (EC:1.4.3.4)
Short name:
MAO-N
Gene namesi
Name:maoN
OrganismiAspergillus niger
Taxonomic identifieri5061 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Peroxisome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000998651 – 495Monoamine oxidase NAdd BLAST495

Proteomic databases

PaxDbiP46882.

Structurei

Secondary structure

1495
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi7 – 10Combined sources4
Turni11 – 13Combined sources3
Beta strandi14 – 17Combined sources4
Beta strandi26 – 29Combined sources4
Beta strandi40 – 45Combined sources6
Helixi49 – 60Combined sources12
Beta strandi65 – 68Combined sources4
Beta strandi70 – 75Combined sources6
Beta strandi80 – 83Combined sources4
Beta strandi86 – 89Combined sources4
Helixi100 – 108Combined sources9
Beta strandi115 – 118Combined sources4
Beta strandi122 – 124Combined sources3
Beta strandi127 – 133Combined sources7
Beta strandi138 – 140Combined sources3
Helixi142 – 157Combined sources16
Beta strandi159 – 162Combined sources4
Turni163 – 167Combined sources5
Helixi180 – 184Combined sources5
Helixi188 – 195Combined sources8
Helixi196 – 198Combined sources3
Helixi201 – 215Combined sources15
Turni219 – 221Combined sources3
Helixi224 – 233Combined sources10
Helixi238 – 246Combined sources9
Beta strandi247 – 250Combined sources4
Helixi254 – 266Combined sources13
Turni267 – 269Combined sources3
Beta strandi271 – 276Combined sources6
Beta strandi279 – 284Combined sources6
Beta strandi286 – 293Combined sources8
Beta strandi298 – 306Combined sources9
Helixi310 – 315Combined sources6
Beta strandi316 – 320Combined sources5
Helixi324 – 332Combined sources9
Beta strandi339 – 346Combined sources8
Helixi348 – 352Combined sources5
Beta strandi353 – 357Combined sources5
Beta strandi359 – 362Combined sources4
Beta strandi365 – 371Combined sources7
Beta strandi377 – 383Combined sources7
Helixi385 – 387Combined sources3
Turni391 – 393Combined sources3
Helixi395 – 403Combined sources9
Beta strandi412 – 417Combined sources6
Turni420 – 422Combined sources3
Turni424 – 426Combined sources3
Beta strandi427 – 430Combined sources4
Helixi437 – 446Combined sources10
Beta strandi452 – 454Combined sources3
Helixi457 – 459Combined sources3
Beta strandi461 – 463Combined sources3
Helixi467 – 485Combined sources19

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2VVLX-ray2.45A/B/C/D/E/F/G/H1-495[»]
2VVMX-ray1.85A/B1-495[»]
3ZDNX-ray2.55A/B/C/D1-495[»]
ProteinModelPortaliP46882.
SMRiP46882.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP46882.

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi493 – 495Microbody targeting signalSequence analysis3

Sequence similaritiesi

Belongs to the flavin monoamine oxidase family.Curated

Phylogenomic databases

eggNOGiENOG410IEV1. Eukaryota.
ENOG410ZJPM. LUCA.

Family and domain databases

Gene3Di3.50.50.60. 3 hits.
InterProiIPR002937. Amino_oxidase.
IPR023753. FAD/NAD-binding_dom.
IPR001613. Flavin_amine_oxidase.
[Graphical view]
PfamiPF01593. Amino_oxidase. 1 hit.
[Graphical view]
PRINTSiPR00757. AMINEOXDASEF.
SUPFAMiSSF51905. SSF51905. 2 hits.

Sequencei

Sequence statusi: Complete.

P46882-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSRDGYQWT PETGLTQGVP SLGVISPPTN IEDTDKDGPW DVIVIGGGYC
60 70 80 90 100
GLTATRDLTV AGFKTLLLEA RDRIGGRSWS SNIDGYPYEM GGTWVHWHQS
110 120 130 140 150
HVWREITRYK MHNALSPSFN FSRGVNHFQL RTNPTTSTYM THEAEDELLR
160 170 180 190 200
SALHKFTNVD GTNGRTVLPF PHDMFYVPEF RKYDEMSYSE RIDQIRDELS
210 220 230 240 250
LNERSSLEAF ILLCSGGTLE NSSFGEFLHW WAMSGYTYQG CMDCLISYKF
260 270 280 290 300
KDGQSAFARR FWEEAAGTGR LGYVFGCPVR SVVNERDAAR VTARDGREFA
310 320 330 340 350
AKRLVCTIPL NVLSTIQFSP ALSTERISAM QAGHVNMCTK VHAEVDNKDM
360 370 380 390 400
RSWTGIAYPF NKLCYAIGDG TTPAGNTHLV CFGTDANHIQ PDEDVRETLK
410 420 430 440 450
AVGQLAPGTF GVKRLVFHNW VKDEFAKGAW FFSRPGMVSE CLQGLREKHR
460 470 480 490
GVVFANSDWA LGWRSFIDGA IEEGTRAARV VLEELGTKRE VKARL
Length:495
Mass (Da):55,617
Last modified:November 1, 1995 - v1
Checksum:i0E614FF09D3C5B3D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L38858 Genomic DNA. Translation: AAA98490.1.
PIRiS55273.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L38858 Genomic DNA. Translation: AAA98490.1.
PIRiS55273.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2VVLX-ray2.45A/B/C/D/E/F/G/H1-495[»]
2VVMX-ray1.85A/B1-495[»]
3ZDNX-ray2.55A/B/C/D1-495[»]
ProteinModelPortaliP46882.
SMRiP46882.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PaxDbiP46882.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG410IEV1. Eukaryota.
ENOG410ZJPM. LUCA.

Enzyme and pathway databases

BRENDAi1.4.3.4. 518.

Miscellaneous databases

EvolutionaryTraceiP46882.

Family and domain databases

Gene3Di3.50.50.60. 3 hits.
InterProiIPR002937. Amino_oxidase.
IPR023753. FAD/NAD-binding_dom.
IPR001613. Flavin_amine_oxidase.
[Graphical view]
PfamiPF01593. Amino_oxidase. 1 hit.
[Graphical view]
PRINTSiPR00757. AMINEOXDASEF.
SUPFAMiSSF51905. SSF51905. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiAOFN_ASPNG
AccessioniPrimary (citable) accession number: P46882
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: November 2, 2016
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.