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Protein

Chitinase 1

Gene

CHT1

Organism
Candida albicans (Yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei147Proton donorPROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidase, Hydrolase
Biological processCarbohydrate metabolism, Chitin degradation, Polysaccharide degradation
LigandChitin-binding

Protein family/group databases

CAZyiGH18. Glycoside Hydrolase Family 18.

Names & Taxonomyi

Protein namesi
Recommended name:
Chitinase 1 (EC:3.2.1.14)
Gene namesi
Name:CHT1
OrganismiCandida albicans (Yeast)
Taxonomic identifieri5476 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17Sequence analysisAdd BLAST17
ChainiPRO_000001192418 – 462Chitinase 1Add BLAST445

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi57N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Structurei

3D structure databases

ProteinModelPortaliP46876.
SMRiP46876.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi237 – 240Poly-Ser4
Compositional biasi305 – 422Thr-richAdd BLAST118

Sequence similaritiesi

Keywords - Domaini

Signal

Family and domain databases

InterProiView protein in InterPro
IPR001223. Glyco_hydro18_cat.
IPR001579. Glyco_hydro_18_chit_AS.
IPR017853. Glycoside_hydrolase_SF.
PfamiView protein in Pfam
PF00704. Glyco_hydro_18. 1 hit.
SUPFAMiSSF51445. SSF51445. 1 hit.
PROSITEiView protein in PROSITE
PS01095. CHITINASE_18. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P46876-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MILNLIILLA ISIVASASNI AAYWGQNAGG DQQTLGDYCS SSPASIIILS
60 70 80 90 100
FLDGFPNLSL NFANQCSGTF SSGLAHCSQI GSDIKSCQQQ GKTILLSLGG
110 120 130 140 150
ATGNYGFSSD SEAVQFAGTL WNKFGGGKDS ERPFDDAIVD GFDFDIENKD
160 170 180 190 200
QTGYAALATQ LRKYFSTGTK SYYLSAAPQC PYPDESVGDL MSQVDLDFAF
210 220 230 240 250
IQFYNNYCSL NQQFNWNSWS NYARGKSIKL YLGLPGSSSS AGSGFVGLST
260 270 280 290 300
VQRVVASIKG DSSFGGISIW DISSAENGGY LNQLYQALSG SGSPAAPSNS
310 320 330 340 350
YQPNTPLTRT YGGSTATASA YISVGFTAGA THGSTTTNDL LAWIDSLFGS
360 370 380 390 400
SQSSVQQYAT PVQSVTATPQ PVAATTTSAP KPTASAFNWF GWFDGTTTST
410 420 430 440 450
TLQTVYSTVP ADQTVYVTLT TTVGSQMLQS LFDKRDVIAE AKSTNLQICW
460
LLFIPLLALI CS
Length:462
Mass (Da):48,916
Last modified:May 27, 2002 - v2
Checksum:i978515D7ABECABCD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U36490 Genomic DNA. Translation: AAC49409.2.

Similar proteinsi

Entry informationi

Entry nameiCHI1_CANAX
AccessioniPrimary (citable) accession number: P46876
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: May 27, 2002
Last modified: May 10, 2017
This is version 87 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families