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Protein

Kinesin-3

Gene

ATK3

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Possible role in mitosis.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi481 – 4888ATPPROSITE-ProRule annotation

GO - Molecular functioni

  • ATPase activity Source: TAIR
  • ATP binding Source: UniProtKB-KW
  • microtubule binding Source: TAIR
  • microtubule motor activity Source: GO_Central

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Motor protein

Keywords - Biological processi

Cell cycle, Cell division, Mitosis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciARA:AT5G54670-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Kinesin-3
Alternative name(s):
Kinesin-like protein C
Gene namesi
Name:ATK3
Synonyms:KATC
Ordered Locus Names:At5g54670
ORF Names:K5F14.1, MRB17.18
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

TAIRiAT5G54670.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Microtubule

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 754754Kinesin-3PRO_0000125382Add
BLAST

Proteomic databases

PaxDbiP46875.
PRIDEiP46875.

PTM databases

iPTMnetiP46875.

Expressioni

Gene expression databases

ExpressionAtlasiP46875. baseline and differential.
GenevisibleiP46875. AT.

Interactioni

GO - Molecular functioni

  • microtubule binding Source: TAIR

Protein-protein interaction databases

BioGridi20800. 2 interactions.
STRINGi3702.AT5G54670.1.

Structurei

3D structure databases

ProteinModelPortaliP46875.
SMRiP46875. Positions 396-731.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini396 – 733338Kinesin motorPROSITE-ProRule annotationAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni1 – 4545GlobularAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili46 – 393348Add
BLAST

Domaini

Composed of three structural domains; a small globular N-terminal, a central alpha-helical coiled coil and a large globular C-terminal which is responsible for the motor activity (it hydrolyzes ATP and binds microtubules).

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. NCD subfamily.PROSITE-ProRule annotation
Contains 1 kinesin motor domain.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiKOG0239. Eukaryota.
COG5059. LUCA.
HOGENOMiHOG000116164.
InParanoidiP46875.
KOiK10405.
OMAiECGGIEF.
OrthoDBiEOG0936041R.
PhylomeDBiP46875.

Family and domain databases

Gene3Di3.40.850.10. 1 hit.
InterProiIPR027640. Kinesin-like_fam.
IPR019821. Kinesin_motor_CS.
IPR001752. Kinesin_motor_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR24115. PTHR24115. 2 hits.
PfamiPF00225. Kinesin. 1 hit.
[Graphical view]
PRINTSiPR00380. KINESINHEAVY.
SMARTiSM00129. KISc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00411. KINESIN_MOTOR_1. 1 hit.
PS50067. KINESIN_MOTOR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P46875-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVGAMANNGR IRSAFPVTNG SKDLTPNSAP ASTTGSEYGP VEFTREDVET
60 70 80 90 100
LLNERIKYKS KFNYKERCEN MMDYIKRLRL CIRWFQELEL DYAFEQEKLK
110 120 130 140 150
NALELNEKHC VDMEVSLKNK EEELNMIIEE LRKNFESVQV QLAREQTEKL
160 170 180 190 200
AANDSLGKEK EARLSVEKAQ AGLTEELGKA QGDLQTANQR IQSVNDMYKL
210 220 230 240 250
LQEYNSSLQL YNSKLQGDLD EAHETIKRGE KERTAIIENI GNLKGQFSAL
260 270 280 290 300
QEQLAASKAS QEDIMKQKGE LVNEIASLKV ELQQVKDDRD RHLVEVKTLQ
310 320 330 340 350
TEATKYNDFK DAITELETTC SSQSTQIRQL QDRLVNSERR LQVSDLSTFE
360 370 380 390 400
KMNEYEDQKQ SIIDLKSRVE EAELKLVEGE KLRKKLHNTI LELKGNIRVF
410 420 430 440 450
CRVRPLLPGE NNGDEGKTIS YPTSLEALGR GIDLMQNAQK HAFTFDKVFA
460 470 480 490 500
PTASQEDVFT EISQLVQSAL DGYKVCIFAY GQTGSGKTYT MMGRPGNVEE
510 520 530 540 550
KGLIPRCLEQ IFETRQSLRS QGWKYELQVS MLEIYNETIR DLLSTNKEAV
560 570 580 590 600
RTDSGVSPQK HAIKHDASGN THVAELTILD VKSSREVSFL LDHAARNRSV
610 620 630 640 650
GKTQMNEQSS RSHFVFTLRI SGVNESTEQQ VQGVLNLIDL AGSERLSKSG
660 670 680 690 700
STGDRLKETQ AINKSLSSLG DVIFALAKKE DHVPFRNSKL TYLLQPCLGG
710 720 730 740 750
DAKTLMFVNI APESSSTGES LCSLRFAARV NACEIGTPRR QTNIKPLENR

LSLG
Length:754
Mass (Da):85,030
Last modified:November 1, 1995 - v1
Checksum:i76091CD5B5D9C531
GO

Sequence cautioni

The sequence BAB09933 differs from that shown. Reason: Erroneous gene model prediction. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D21138 mRNA. Translation: BAA04674.1.
AB022214 Genomic DNA. Translation: BAB09933.1. Sequence problems.
CP002688 Genomic DNA. Translation: AED96525.1.
BT003156 mRNA. Translation: AAO24588.1.
PIRiS48020.
RefSeqiNP_568811.1. NM_124848.2.
UniGeneiAt.20653.

Genome annotation databases

EnsemblPlantsiAT5G54670.1; AT5G54670.1; AT5G54670.
GeneIDi835556.
GrameneiAT5G54670.1; AT5G54670.1; AT5G54670.
KEGGiath:AT5G54670.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D21138 mRNA. Translation: BAA04674.1.
AB022214 Genomic DNA. Translation: BAB09933.1. Sequence problems.
CP002688 Genomic DNA. Translation: AED96525.1.
BT003156 mRNA. Translation: AAO24588.1.
PIRiS48020.
RefSeqiNP_568811.1. NM_124848.2.
UniGeneiAt.20653.

3D structure databases

ProteinModelPortaliP46875.
SMRiP46875. Positions 396-731.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi20800. 2 interactions.
STRINGi3702.AT5G54670.1.

PTM databases

iPTMnetiP46875.

Proteomic databases

PaxDbiP46875.
PRIDEiP46875.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT5G54670.1; AT5G54670.1; AT5G54670.
GeneIDi835556.
GrameneiAT5G54670.1; AT5G54670.1; AT5G54670.
KEGGiath:AT5G54670.

Organism-specific databases

TAIRiAT5G54670.

Phylogenomic databases

eggNOGiKOG0239. Eukaryota.
COG5059. LUCA.
HOGENOMiHOG000116164.
InParanoidiP46875.
KOiK10405.
OMAiECGGIEF.
OrthoDBiEOG0936041R.
PhylomeDBiP46875.

Enzyme and pathway databases

BioCyciARA:AT5G54670-MONOMER.

Miscellaneous databases

PROiP46875.

Gene expression databases

ExpressionAtlasiP46875. baseline and differential.
GenevisibleiP46875. AT.

Family and domain databases

Gene3Di3.40.850.10. 1 hit.
InterProiIPR027640. Kinesin-like_fam.
IPR019821. Kinesin_motor_CS.
IPR001752. Kinesin_motor_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR24115. PTHR24115. 2 hits.
PfamiPF00225. Kinesin. 1 hit.
[Graphical view]
PRINTSiPR00380. KINESINHEAVY.
SMARTiSM00129. KISc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00411. KINESIN_MOTOR_1. 1 hit.
PS50067. KINESIN_MOTOR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiATK3_ARATH
AccessioniPrimary (citable) accession number: P46875
Secondary accession number(s): Q9FH38
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: September 7, 2016
This is version 119 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.