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Reviewed, UniProtKB/Swiss-Prot P46776 (RL27A_HUMAN)

Last modified November 4, 2008. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    60S ribosomal protein L27a
Gene names
Name: RPL27A
OrganismHomo sapiens (Human)
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length148 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level.

General annotation (Comments)

Sequence similarities

Belongs to the ribosomal protein L15P family.

Ontologies

Keywords

   Molecular functionRibonucleoprotein
Ribosomal protein

Gene Ontology (GO)

   Biological processtranslational elongation

Inferred from Experiment. Source: Reactome

   Cellular componentcytosolic large ribosomal subunit Ref.1

Traceable author statement. Source: ProtInc

   Molecular functionRNA binding Ref.1

Traceable author statement. Source: ProtInc

structural constituent of ribosome Ref.1

Traceable author statement. Source: ProtInc

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed By similarity
Chain2 – 14814760S ribosomal protein L27a
PRO_0000104879

Sequences

Sequence LengthMass (Da)Tools
P46776-1 [UniParc].

Last modified January 23, 2007. Version 2.
Checksum: CB5E09C91507798F

FASTA14816,561
        10         20         30         40         50         60 
MPSRLRKTRK LRGHVSHGHG RIGKHRKHPG GRGNAGGLHH HRINFDKYHP GYFGKVGMKH 

        70         80         90        100        110        120 
YHLKRNQSFC PTVNLDKLWT LVSEQTRVNA AKNKTGAAPI IDVVRSGYYK VLGKGKLPKQ 

       130        140 
PVIVKAKFFS RRAEEKIKSV GGACVLVA 

« Hide

References

« Hide 'large scale' references
[1]"Cloning, sequencing and expression of the L5, L21, L27a, L28, S5, S9, S10 and S29 human ribosomal protein mRNAs."
Frigerio J.-M., Dagorn J.-C., Iovanna J.L.
Biochim. Biophys. Acta 1262:64-68(1995) [PubMed: 7772601] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Tissue: Colon.
[2]"Genomic structure and chromosome location of RPL27A/Rpl27a, the genes encoding human and mouse ribosomal protein L27A."
Kusuda J., Hirai M., Tanuma R., Hirata M., Hashimoto K.
Cytogenet. Cell Genet. 85:248-251(1999) [PubMed: 10449908] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Kidney and Lymph.
[4]"A map of 75 human ribosomal protein genes."
Kenmochi N., Kawaguchi T., Rozen S., Davis E., Goodman N., Hudson T.J., Tanaka T., Page D.C.
Genome Res. 8:509-523(1998) [PubMed: 9582194] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 73-106.

Cross-references

Sequence databases

U14968 mRNA. Translation: AAA85656.1.
AB020236 Genomic DNA. Translation: BAA77361.1.
BC005326 mRNA. Translation: AAH05326.1.
BC020169 mRNA. Translation: AAH20169.1.
AB007178 Genomic DNA. Translation: BAA25837.1.
PIRS55914.
RefSeqNP_000981.1.
UniGeneHs.523463

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

IntActP46776.

PTM databases

PhosphoSiteP46776.

2-D gel databases

SWISS-2DPAGEP46776.

Genome annotation databases

EnsemblENSG00000166441. Homo sapiens. [Contig view]
GeneID6157.
KEGGhsa:6157.

Organism-specific databases

HGNCHGNC:10329. RPL27A.
MIM603637. gene.
PharmGKBPA34708.
GenAtlasSearch...
GeneCardsSearch...

Phylogenomic databases

HOGENOMP46776.
HOVERGENP46776.

Enzyme and pathway databases

ReactomeREACT_1762. 3' -UTR-mediated translational regulation.
REACT_6167. Influenza Infection.
REACT_71. Gene Expression.

Gene expression databases

CleanExHS_RPL27A.
GermOnlineENSG00000166441. Homo sapiens.

Family and domain databases

InterProIPR001196. Ribosomal_L15.
[Graphical view]
PfamPF00256. L15. 1 hit.
[Graphical view]
PROSITEPS00475. RIBOSOMAL_L15. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

LinkHubP46776.
NextBio23911.
SOURCESearch...

Entry information

Entry nameRL27A_HUMAN
AccessionPrimary (citable) accession number: P46776
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: January 23, 2007
Last modified: November 4, 2008
This is version 66 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHPI (Human Proteome Initiative)

Relevant documents

Human chromosome 11

Human chromosome 11: entries, gene names and cross-references to MIM

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Ribosomal proteins

Ribosomal proteins families and list of entries

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents