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P46671 (FAR3_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 85. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Factor arrest protein 3
Gene names
Name:FAR3
Ordered Locus Names:YMR052W
ORF Names:YM9796.05
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length204 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Participates in the control of the reentry into the cell cycle following pheromone treatment. Ref.4

Subunit structure

Component of a complex at least composed of FAR3, FAR7, FAR8, FAR10, FAR11 and VPS64.

Subcellular location

Endoplasmic reticulum Ref.5.

Miscellaneous

Present with 1540 molecules/cell in log phase SD medium.

Binary interactions

With

Entry

#Exp.

IntAct

Notes

FAR7P435924EBI-6789,EBI-22932

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 204204Factor arrest protein 3
PRO_0000087191

Experimental info

Sequence conflict61S → T in AAB39035. Ref.1
Sequence conflict1311S → T in AAB39035. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P46671 [UniParc].

Last modified October 1, 1996. Version 2.
Checksum: DCDA9A5713B588B5

FASTA20424,032
        10         20         30         40         50         60 
MNSGGSDSFD YLLQLTKALS AECRANRQET DRIELLLKRL AKQSGISYDN LSKNIIPDSW 

        70         80         90        100        110        120 
KDNASQKASP PTEAQKLISE NFKLIYEIEK QEYFNTKAVA LINNINEHFS YIKNFIDEQN 

       130        140        150        160        170        180 
AIRERNIATF SSEKLDERNK SLQQNYESLK TENEETKKKL HSIIKQFEKL LKEVDWDRIS 

       190        200 
KDSRDYSRFK KQLEYLQDTY QVLK 

« Hide

References

« Hide 'large scale' references
[1]"Localization of the FAR3 gene: genetic mapping and molecular cloning using a chromosome walk-'n'-roll strategy."
Horecka J.
Yeast 11:691-696(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: SC252.
[2]"The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII."
Bowman S., Churcher C.M., Badcock K., Brown D., Chillingworth T., Connor R., Dedman K., Devlin K., Gentles S., Hamlin N., Hunt S., Jagels K., Lye G., Moule S., Odell C., Pearson D., Rajandream M.A., Rice P. expand/collapse author list , Skelton J., Walsh S.V., Whitehead S., Barrell B.G.
Nature 387:90-93(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"Far3 and five interacting proteins prevent premature recovery from pheromone arrest in the budding yeast Saccharomyces cerevisiae."
Kemp H.A., Sprague G.F. Jr.
Mol. Cell. Biol. 23:1750-1763(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION, INTERACTION WITH FAR7; FAR8; FAR10; FAR11 AND VPS64.
[5]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[6]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U35609 Genomic DNA. Translation: AAB39035.1.
Z49703 Genomic DNA. Translation: CAA89762.1.
BK006946 Genomic DNA. Translation: DAA09951.1.
PIRS54552.
RefSeqNP_013767.1. NM_001182550.1.

3D structure databases

ProteinModelPortalP46671.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid35228. 146 interactions.
DIPDIP-1314N.
IntActP46671. 6 interactions.
MINTMINT-393191.
STRING4932.YMR052W.

Proteomic databases

PaxDbP46671.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYMR052W; YMR052W; YMR052W.
GeneID855073.
KEGGsce:YMR052W.

Organism-specific databases

CYGDYMR052w.
SGDS000004656. FAR3.

Phylogenomic databases

eggNOGNOG44390.
HOGENOMHOG000112501.
OMANDGHINA.
OrthoDBEOG7VDZ24.

Enzyme and pathway databases

BioCycYEAST:G3O-32757-MONOMER.

Gene expression databases

GenevestigatorP46671.

Family and domain databases

ProtoNetSearch...

Other

NextBio978348.

Entry information

Entry nameFAR3_YEAST
AccessionPrimary (citable) accession number: P46671
Secondary accession number(s): D6VZM7
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: October 1, 1996
Last modified: February 19, 2014
This is version 85 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome XIII

Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD