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Protein

Factor arrest protein 3

Gene

FAR3

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Participates in the control of the reentry into the cell cycle following pheromone treatment.1 Publication

GO - Biological processi

  1. re-entry into mitotic cell cycle after pheromone arrest Source: SGD
Complete GO annotation...

Keywords - Biological processi

Cell cycle

Enzyme and pathway databases

BioCyciYEAST:G3O-32757-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Factor arrest protein 3
Gene namesi
Name:FAR3
Ordered Locus Names:YMR052W
ORF Names:YM9796.05
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome XIII

Organism-specific databases

CYGDiYMR052w.
SGDiS000004656. FAR3.

Subcellular locationi

Endoplasmic reticulum 1 Publication

GO - Cellular componenti

  1. endoplasmic reticulum Source: SGD
  2. Golgi cis cisterna Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 204204Factor arrest protein 3PRO_0000087191Add
BLAST

Proteomic databases

MaxQBiP46671.
PaxDbiP46671.

Expressioni

Gene expression databases

GenevestigatoriP46671.

Interactioni

Subunit structurei

Component of a complex at least composed of FAR3, FAR7, FAR8, FAR10, FAR11 and VPS64.

Binary interactionsi

WithEntry#Exp.IntActNotes
FAR7P435924EBI-6789,EBI-22932

Protein-protein interaction databases

BioGridi35228. 146 interactions.
DIPiDIP-1314N.
IntActiP46671. 6 interactions.
MINTiMINT-393191.
STRINGi4932.YMR052W.

Structurei

3D structure databases

ProteinModelPortaliP46671.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiNOG44390.
HOGENOMiHOG000112501.
InParanoidiP46671.
OMAiNDGHINA.
OrthoDBiEOG7VDZ24.

Sequencei

Sequence statusi: Complete.

P46671-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSGGSDSFD YLLQLTKALS AECRANRQET DRIELLLKRL AKQSGISYDN
60 70 80 90 100
LSKNIIPDSW KDNASQKASP PTEAQKLISE NFKLIYEIEK QEYFNTKAVA
110 120 130 140 150
LINNINEHFS YIKNFIDEQN AIRERNIATF SSEKLDERNK SLQQNYESLK
160 170 180 190 200
TENEETKKKL HSIIKQFEKL LKEVDWDRIS KDSRDYSRFK KQLEYLQDTY

QVLK
Length:204
Mass (Da):24,032
Last modified:October 1, 1996 - v2
Checksum:iDCDA9A5713B588B5
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti6 – 61S → T in AAB39035 (PubMed:7483842).Curated
Sequence conflicti131 – 1311S → T in AAB39035 (PubMed:7483842).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U35609 Genomic DNA. Translation: AAB39035.1.
Z49703 Genomic DNA. Translation: CAA89762.1.
BK006946 Genomic DNA. Translation: DAA09951.1.
PIRiS54552.
RefSeqiNP_013767.1. NM_001182550.1.

Genome annotation databases

EnsemblFungiiYMR052W; YMR052W; YMR052W.
GeneIDi855073.
KEGGisce:YMR052W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U35609 Genomic DNA. Translation: AAB39035.1.
Z49703 Genomic DNA. Translation: CAA89762.1.
BK006946 Genomic DNA. Translation: DAA09951.1.
PIRiS54552.
RefSeqiNP_013767.1. NM_001182550.1.

3D structure databases

ProteinModelPortaliP46671.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi35228. 146 interactions.
DIPiDIP-1314N.
IntActiP46671. 6 interactions.
MINTiMINT-393191.
STRINGi4932.YMR052W.

Proteomic databases

MaxQBiP46671.
PaxDbiP46671.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYMR052W; YMR052W; YMR052W.
GeneIDi855073.
KEGGisce:YMR052W.

Organism-specific databases

CYGDiYMR052w.
SGDiS000004656. FAR3.

Phylogenomic databases

eggNOGiNOG44390.
HOGENOMiHOG000112501.
InParanoidiP46671.
OMAiNDGHINA.
OrthoDBiEOG7VDZ24.

Enzyme and pathway databases

BioCyciYEAST:G3O-32757-MONOMER.

Miscellaneous databases

NextBioi978348.

Gene expression databases

GenevestigatoriP46671.

Family and domain databases

ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Localization of the FAR3 gene: genetic mapping and molecular cloning using a chromosome walk-'n'-roll strategy."
    Horecka J.
    Yeast 11:691-696(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: SC252.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  4. "Far3 and five interacting proteins prevent premature recovery from pheromone arrest in the budding yeast Saccharomyces cerevisiae."
    Kemp H.A., Sprague G.F. Jr.
    Mol. Cell. Biol. 23:1750-1763(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, INTERACTION WITH FAR7; FAR8; FAR10; FAR11 AND VPS64.
  5. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  6. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiFAR3_YEAST
AccessioniPrimary (citable) accession number: P46671
Secondary accession number(s): D6VZM7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: October 1, 1996
Last modified: January 7, 2015
This is version 90 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 1540 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome XIII
    Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.