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P46671

- FAR3_YEAST

UniProt

P46671 - FAR3_YEAST

Protein

Factor arrest protein 3

Gene

FAR3

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 88 (01 Oct 2014)
      Sequence version 2 (01 Oct 1996)
      Previous versions | rss
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    Functioni

    Participates in the control of the reentry into the cell cycle following pheromone treatment.1 Publication

    GO - Molecular functioni

    1. protein binding Source: IntAct

    GO - Biological processi

    1. re-entry into mitotic cell cycle after pheromone arrest Source: SGD

    Keywords - Biological processi

    Cell cycle

    Enzyme and pathway databases

    BioCyciYEAST:G3O-32757-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Factor arrest protein 3
    Gene namesi
    Name:FAR3
    Ordered Locus Names:YMR052W
    ORF Names:YM9796.05
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome XIII

    Organism-specific databases

    CYGDiYMR052w.
    SGDiS000004656. FAR3.

    Subcellular locationi

    Endoplasmic reticulum 1 Publication

    GO - Cellular componenti

    1. endoplasmic reticulum Source: SGD
    2. Golgi cis cisterna Source: SGD

    Keywords - Cellular componenti

    Endoplasmic reticulum

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 204204Factor arrest protein 3PRO_0000087191Add
    BLAST

    Proteomic databases

    MaxQBiP46671.
    PaxDbiP46671.

    Expressioni

    Gene expression databases

    GenevestigatoriP46671.

    Interactioni

    Subunit structurei

    Component of a complex at least composed of FAR3, FAR7, FAR8, FAR10, FAR11 and VPS64.

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    FAR7P435924EBI-6789,EBI-22932

    Protein-protein interaction databases

    BioGridi35228. 146 interactions.
    DIPiDIP-1314N.
    IntActiP46671. 6 interactions.
    MINTiMINT-393191.
    STRINGi4932.YMR052W.

    Structurei

    3D structure databases

    ProteinModelPortaliP46671.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiNOG44390.
    HOGENOMiHOG000112501.
    OMAiNDGHINA.
    OrthoDBiEOG7VDZ24.

    Sequencei

    Sequence statusi: Complete.

    P46671-1 [UniParc]FASTAAdd to Basket

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    MNSGGSDSFD YLLQLTKALS AECRANRQET DRIELLLKRL AKQSGISYDN    50
    LSKNIIPDSW KDNASQKASP PTEAQKLISE NFKLIYEIEK QEYFNTKAVA 100
    LINNINEHFS YIKNFIDEQN AIRERNIATF SSEKLDERNK SLQQNYESLK 150
    TENEETKKKL HSIIKQFEKL LKEVDWDRIS KDSRDYSRFK KQLEYLQDTY 200
    QVLK 204
    Length:204
    Mass (Da):24,032
    Last modified:October 1, 1996 - v2
    Checksum:iDCDA9A5713B588B5
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti6 – 61S → T in AAB39035. (PubMed:7483842)Curated
    Sequence conflicti131 – 1311S → T in AAB39035. (PubMed:7483842)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U35609 Genomic DNA. Translation: AAB39035.1.
    Z49703 Genomic DNA. Translation: CAA89762.1.
    BK006946 Genomic DNA. Translation: DAA09951.1.
    PIRiS54552.
    RefSeqiNP_013767.1. NM_001182550.1.

    Genome annotation databases

    EnsemblFungiiYMR052W; YMR052W; YMR052W.
    GeneIDi855073.
    KEGGisce:YMR052W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U35609 Genomic DNA. Translation: AAB39035.1 .
    Z49703 Genomic DNA. Translation: CAA89762.1 .
    BK006946 Genomic DNA. Translation: DAA09951.1 .
    PIRi S54552.
    RefSeqi NP_013767.1. NM_001182550.1.

    3D structure databases

    ProteinModelPortali P46671.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 35228. 146 interactions.
    DIPi DIP-1314N.
    IntActi P46671. 6 interactions.
    MINTi MINT-393191.
    STRINGi 4932.YMR052W.

    Proteomic databases

    MaxQBi P46671.
    PaxDbi P46671.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YMR052W ; YMR052W ; YMR052W .
    GeneIDi 855073.
    KEGGi sce:YMR052W.

    Organism-specific databases

    CYGDi YMR052w.
    SGDi S000004656. FAR3.

    Phylogenomic databases

    eggNOGi NOG44390.
    HOGENOMi HOG000112501.
    OMAi NDGHINA.
    OrthoDBi EOG7VDZ24.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-32757-MONOMER.

    Miscellaneous databases

    NextBioi 978348.

    Gene expression databases

    Genevestigatori P46671.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Localization of the FAR3 gene: genetic mapping and molecular cloning using a chromosome walk-'n'-roll strategy."
      Horecka J.
      Yeast 11:691-696(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: SC252.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    3. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    4. "Far3 and five interacting proteins prevent premature recovery from pheromone arrest in the budding yeast Saccharomyces cerevisiae."
      Kemp H.A., Sprague G.F. Jr.
      Mol. Cell. Biol. 23:1750-1763(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, INTERACTION WITH FAR7; FAR8; FAR10; FAR11 AND VPS64.
    5. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    6. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiFAR3_YEAST
    AccessioniPrimary (citable) accession number: P46671
    Secondary accession number(s): D6VZM7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: October 1, 1996
    Last modified: October 1, 2014
    This is version 88 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Present with 1540 molecules/cell in log phase SD medium.1 Publication

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    2. Yeast chromosome XIII
      Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names

    External Data

    Dasty 3