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Protein

Homeobox-leucine zipper protein HAT14

Gene

HAT14

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Probable transcription factor.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi187 – 246HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

  • DNA binding transcription factor activity Source: TAIR
  • sequence-specific DNA binding Source: InterPro

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Homeobox-leucine zipper protein HAT14
Alternative name(s):
Homeodomain-leucine zipper protein HAT14
Short name:
HD-ZIP protein 14
Gene namesi
Name:HAT14
Ordered Locus Names:At5g06710
ORF Names:MPH15.6
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

AraportiAT5G06710
TAIRilocus:2170194 AT5G06710

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000491401 – 336Homeobox-leucine zipper protein HAT14Add BLAST336

Proteomic databases

PaxDbiP46665

PTM databases

iPTMnetiP46665

Expressioni

Gene expression databases

ExpressionAtlasiP46665 baseline and differential
GenevisibleiP46665 AT

Interactioni

Protein-protein interaction databases

BioGridi15839, 8 interactors
IntActiP46665, 8 interactors
STRINGi3702.AT5G06710.1

Structurei

3D structure databases

ProteinModelPortaliP46665
SMRiP46665
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni254 – 275Leucine-zipperAdd BLAST22

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi121 – 128Poly-Glu8

Sequence similaritiesi

Keywords - Domaini

Homeobox

Phylogenomic databases

eggNOGiKOG0483 Eukaryota
ENOG410Z2UE LUCA
HOGENOMiHOG000241612
InParanoidiP46665
KOiK09338
OMAiCERDRDN
OrthoDBiEOG09360QI5
PhylomeDBiP46665

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR003106 Leu_zip_homeo
PfamiView protein in Pfam
PF02183 HALZ, 1 hit
PF00046 Homeobox, 1 hit
SMARTiView protein in SMART
SM00340 HALZ, 1 hit
SM00389 HOX, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS00027 HOMEOBOX_1, 1 hit
PS50071 HOMEOBOX_2, 1 hit

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: P46665-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MELALSLGDN TKKQFSFMEK NSKINNPSVS STSTSEKDLG FCMALDVAFG
60 70 80 90 100
GHRSLSSSSS PSVEDEKKKP APRAKKSDEF RVSSSVDPPL QLQLHFPNWL
110 120 130 140 150
PENSKGRQGG RMPLGAATVV EEEEEEEEAV PSMSVSPPDS VTSSFQLDFG
160 170 180 190 200
IKSYGYERRS NKRDIDDEVE RSASRASNED NDDENGSTRK KLRLSKDQSA
210 220 230 240 250
FLEDSFKEHS TLNPKQKIAL AKQLNLRPRQ VEVWFQNRRA RTKLKQTEVD
260 270 280 290 300
CEYLKRCCES LTEENRRLQK EVKELRTLKT STPFYMQLPA TTLTMCPSCE
310 320 330
RVATSAAQPS TSAAHNLCLS TSSLIPVKPR PAKQVS
Length:336
Mass (Da):37,603
Last modified:May 10, 2005 - v3
Checksum:iBB68D0EFB45EFCA7
GO
Isoform 2 (identifier: P46665-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     215-237: KQKIALAKQLNLRPRQVEVWFQN → VRVPFFTVFIYLKFVFLEFILFF
     238-336: Missing.

Note: Derived from EST data. No experimental confirmation available.
Show »
Length:237
Mass (Da):26,602
Checksum:iE73BF4CAAD8E13A7
GO

Sequence cautioni

The sequence BAB09805 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti203E → K in AAO64814 (PubMed:14593172).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_033326215 – 237KQKIA…VWFQN → VRVPFFTVFIYLKFVFLEFI LFF in isoform 2. CuratedAdd BLAST23
Alternative sequenceiVSP_033327238 – 336Missing in isoform 2. CuratedAdd BLAST99

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ431182 mRNA Translation: CAD24012.2
AP002032 Genomic DNA Translation: BAB09805.1 Sequence problems.
CP002688 Genomic DNA Translation: AED91053.1
CP002688 Genomic DNA Translation: AED91054.1
CP002688 Genomic DNA Translation: ANM70497.1
BT005879 mRNA Translation: AAO64814.1
AK227423 mRNA Translation: BAE99427.1
U09334 mRNA Translation: AAA56900.1
PIRiT52367
RefSeqiNP_001332103.1, NM_001342900.1 [P46665-2]
NP_196289.2, NM_120754.5 [P46665-1]
NP_974743.1, NM_203014.3 [P46665-2]
UniGeneiAt.357

Genome annotation databases

EnsemblPlantsiAT5G06710.1; AT5G06710.1; AT5G06710 [P46665-1]
AT5G06710.2; AT5G06710.2; AT5G06710 [P46665-2]
AT5G06710.3; AT5G06710.3; AT5G06710 [P46665-2]
GeneIDi830560
GrameneiAT5G06710.1; AT5G06710.1; AT5G06710 [P46665-1]
AT5G06710.2; AT5G06710.2; AT5G06710 [P46665-2]
AT5G06710.3; AT5G06710.3; AT5G06710 [P46665-2]
KEGGiath:AT5G06710

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiHAT14_ARATH
AccessioniPrimary (citable) accession number: P46665
Secondary accession number(s): Q0WTX1, Q3E9K4, Q84TE1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: May 10, 2005
Last modified: April 25, 2018
This is version 136 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health