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Protein

Homeobox-leucine zipper protein HAT14

Gene

HAT14

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Probable transcription factor.By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi187 – 24660HomeoboxPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  • sequence-specific DNA binding Source: InterPro
  • transcription factor activity, sequence-specific DNA binding Source: TAIR

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Homeobox-leucine zipper protein HAT14
Alternative name(s):
Homeodomain-leucine zipper protein HAT14
Short name:
HD-ZIP protein 14
Gene namesi
Name:HAT14
Ordered Locus Names:At5g06710
ORF Names:MPH15.6
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

TAIRiAT5G06710.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 336336Homeobox-leucine zipper protein HAT14PRO_0000049140Add
BLAST

Proteomic databases

PaxDbiP46665.
PRIDEiP46665.

Expressioni

Gene expression databases

GenevisibleiP46665. AT.

Interactioni

Protein-protein interaction databases

BioGridi15839. 8 interactions.
IntActiP46665. 8 interactions.
STRINGi3702.AT5G06710.1.

Structurei

3D structure databases

ProteinModelPortaliP46665.
SMRiP46665. Positions 194-243.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni254 – 27522Leucine-zipperAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi121 – 1288Poly-Glu

Sequence similaritiesi

Contains 1 homeobox DNA-binding domain.PROSITE-ProRule annotation

Keywords - Domaini

Homeobox

Phylogenomic databases

eggNOGiKOG0483. Eukaryota.
ENOG410Z2UE. LUCA.
HOGENOMiHOG000241612.
InParanoidiP46665.
KOiK09338.
OMAiCERDRDN.
OrthoDBiEOG09360QI5.
PhylomeDBiP46665.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR003106. Leu_zip_homeo.
[Graphical view]
PfamiPF02183. HALZ. 1 hit.
PF00046. Homeobox. 1 hit.
[Graphical view]
SMARTiSM00340. HALZ. 1 hit.
SM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: P46665-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MELALSLGDN TKKQFSFMEK NSKINNPSVS STSTSEKDLG FCMALDVAFG
60 70 80 90 100
GHRSLSSSSS PSVEDEKKKP APRAKKSDEF RVSSSVDPPL QLQLHFPNWL
110 120 130 140 150
PENSKGRQGG RMPLGAATVV EEEEEEEEAV PSMSVSPPDS VTSSFQLDFG
160 170 180 190 200
IKSYGYERRS NKRDIDDEVE RSASRASNED NDDENGSTRK KLRLSKDQSA
210 220 230 240 250
FLEDSFKEHS TLNPKQKIAL AKQLNLRPRQ VEVWFQNRRA RTKLKQTEVD
260 270 280 290 300
CEYLKRCCES LTEENRRLQK EVKELRTLKT STPFYMQLPA TTLTMCPSCE
310 320 330
RVATSAAQPS TSAAHNLCLS TSSLIPVKPR PAKQVS
Length:336
Mass (Da):37,603
Last modified:May 10, 2005 - v3
Checksum:iBB68D0EFB45EFCA7
GO
Isoform 2 (identifier: P46665-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     215-237: KQKIALAKQLNLRPRQVEVWFQN → VRVPFFTVFIYLKFVFLEFILFF
     238-336: Missing.

Note: Derived from EST data. No experimental confirmation available.
Show »
Length:237
Mass (Da):26,602
Checksum:iE73BF4CAAD8E13A7
GO

Sequence cautioni

The sequence BAB09805 differs from that shown. Reason: Erroneous gene model prediction. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti203 – 2031E → K in AAO64814 (PubMed:14593172).Curated

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei215 – 23723KQKIA…VWFQN → VRVPFFTVFIYLKFVFLEFI LFF in isoform 2. CuratedVSP_033326Add
BLAST
Alternative sequencei238 – 33699Missing in isoform 2. CuratedVSP_033327Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ431182 mRNA. Translation: CAD24012.2.
AP002032 Genomic DNA. Translation: BAB09805.1. Sequence problems.
CP002688 Genomic DNA. Translation: AED91053.1.
CP002688 Genomic DNA. Translation: AED91054.1.
BT005879 mRNA. Translation: AAO64814.1.
AK227423 mRNA. Translation: BAE99427.1.
U09334 mRNA. Translation: AAA56900.1.
PIRiT52367.
RefSeqiNP_196289.2. NM_120754.4. [P46665-1]
NP_974743.1. NM_203014.2. [P46665-2]
UniGeneiAt.357.

Genome annotation databases

EnsemblPlantsiAT5G06710.1; AT5G06710.1; AT5G06710. [P46665-1]
GeneIDi830560.
KEGGiath:AT5G06710.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ431182 mRNA. Translation: CAD24012.2.
AP002032 Genomic DNA. Translation: BAB09805.1. Sequence problems.
CP002688 Genomic DNA. Translation: AED91053.1.
CP002688 Genomic DNA. Translation: AED91054.1.
BT005879 mRNA. Translation: AAO64814.1.
AK227423 mRNA. Translation: BAE99427.1.
U09334 mRNA. Translation: AAA56900.1.
PIRiT52367.
RefSeqiNP_196289.2. NM_120754.4. [P46665-1]
NP_974743.1. NM_203014.2. [P46665-2]
UniGeneiAt.357.

3D structure databases

ProteinModelPortaliP46665.
SMRiP46665. Positions 194-243.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi15839. 8 interactions.
IntActiP46665. 8 interactions.
STRINGi3702.AT5G06710.1.

Proteomic databases

PaxDbiP46665.
PRIDEiP46665.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT5G06710.1; AT5G06710.1; AT5G06710. [P46665-1]
GeneIDi830560.
KEGGiath:AT5G06710.

Organism-specific databases

TAIRiAT5G06710.

Phylogenomic databases

eggNOGiKOG0483. Eukaryota.
ENOG410Z2UE. LUCA.
HOGENOMiHOG000241612.
InParanoidiP46665.
KOiK09338.
OMAiCERDRDN.
OrthoDBiEOG09360QI5.
PhylomeDBiP46665.

Miscellaneous databases

PROiP46665.

Gene expression databases

GenevisibleiP46665. AT.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR003106. Leu_zip_homeo.
[Graphical view]
PfamiPF02183. HALZ. 1 hit.
PF00046. Homeobox. 1 hit.
[Graphical view]
SMARTiSM00340. HALZ. 1 hit.
SM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiHAT14_ARATH
AccessioniPrimary (citable) accession number: P46665
Secondary accession number(s): Q0WTX1, Q3E9K4, Q84TE1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: May 10, 2005
Last modified: September 7, 2016
This is version 122 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.